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Official Full Name toll-like receptor 9
Background Toll-like receptor 9 is a protein that in humans is encoded by the TLR9 gene. TLR9 has also been designated as CD289 (cluster of differentiation 289).
Synonyms CD 289; CD289; TLR 9; TLR9; TLR9_HUMAN; Toll like receptor 9; Toll like receptor 9 isoform A precursor; Toll like receptor 9 isoform B; Toll-like receptor 9; CD289 antigen
    • Species :
    • Human
    • Mouse
    • Rat
    • Rhesus Macaque
    • Rhesus monkey
    • Zebrafish
    • Source :
    • CHO
    • E.coli
    • HEK293
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • Fc
    • hIgG1
    • hIgG4
    • His
    • GST
    • T7
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human TLR9-1042HCL Recombinant Human TLR9 293 Cell Lysate HEK293 N/A
    Human TLR9-452H Recombinant Human TLR9 protein Wheat Germ N/A
    Human TLR9-48H Recombinant Human TLR9 protein E.coli N/A
    Human TLR9-695H Recombinant Human TLR9 protein, His-tagged E.coli His
    Mouse TLR9-16831M Recombinant Mouse TLR9 Protein Mammalian Cell His
    Mouse Tlr9-372M Recombinant Mouse Tlr9 protein, Fc-tagged CHO Fc
    Mouse Tlr9-696M Recombinant Mouse Tlr9 protein, His & GST-tagged E.coli His/GST
    Rat Tlr9-697R Recombinant Rat Tlr9 protein, His & T7-tagged E.coli His/T7
    Rhesus monkey TLR9-1682R Recombinant Rhesus Monkey TLR9 Protein HEK293 N/A
    Rhesus monkey TLR9-1683R Recombinant Rhesus Monkey TLR9 Protein, hIgG1-tagged HEK293 hIgG1
    Rhesus monkey TLR9-1684R Recombinant Rhesus Monkey TLR9 Protein, hIgG4-tagged HEK293 hIgG4
    Rhesus Macaque TLR9-4738R Recombinant Rhesus monkey TLR9 Protein, His-tagged Mammalian Cell His
    Zebrafish TLR9-7078Z Recombinant Zebrafish TLR9 Mammalian Cell His

    TLR9 involved in several pathways and played different roles in them. We selected most pathways TLR9 participated on our site, such as Toll-like receptor signaling pathway, Chagas disease (American trypanosomiasis), African trypanosomiasis, which may be useful for your reference. Also, other proteins which involved in the same pathway with TLR9 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Toll-like receptor signaling pathway MAPK12B; MAP2K2A; IRAK4; SPP1; Ifna11; IL12A; TMED7-TICAM2; PIK3CA; Ifna15; IKBKG
    Chagas disease (American trypanosomiasis) MAPK13; GNAS; TICAM1; PIK3R1; PIK3R3; SMAD2; SMAD3; CCL3; CCL3L1; C1QC
    African trypanosomiasis PLCB4; TLR9; HBB-B2; SELE; HBA-A2; IFNG; ICAM1; HBB; PLCB3; IDO1
    Tuberculosis TLR9; TLR4; IFNA16; cgr2b; BAX; IFNA1; IFNA21; RELA; HLA-DOB; PLK3
    Herpes simplex infection TBP; C3; NFKB1; IFN-a; MCRS1; SFRS3B; GLTSCR2; H2-AA; IRF7; IFNA14

    TLR9 has several biochemical functions, for example, interleukin-1 receptor binding, siRNA binding, transmembrane signaling receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by TLR9 itself. We selected most functions TLR9 had, and list some proteins which have the same functions with TLR9. You can find most of the proteins on our site.

    Function Related Protein
    interleukin-1 receptor binding IL1RN; IL1B; IRAK1; Il1f6; IL36G; IL36RN; IL1F10; IRAK4; IL37; IL36B
    siRNA binding TLR7; AGO2; TLR9; DICER1; TARBP2; MECP2
    transmembrane signaling receptor activity FZD3B; Cd79a, Cd79b; DNER; TLR7; ICAM1; SIGLEC8; GHRHRA; GPR113; OR4D6; GABRQ

    TLR9 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TLR9 here. Most of them are supplied by our site. Hope this information will be useful for your research of TLR9.


    Li, XY; Yue, Y; et al. Extracellular, but not intracellular HMGB1, facilitates self-DNA induced macrophage activation via promoting DNA accumulation in endosomes and contributes to the pathogenesis of lupus nephritis. MOLECULAR IMMUNOLOGY 65:177-188(2015).
    Chan, E; Kwak, EL; et al. Open-label phase 1b study of FOLFIRI plus cetuximab plus IMO-2055 in patients with colorectal cancer who have progressed following chemotherapy for advanced or metastatic disease. CANCER CHEMOTHERAPY AND PHARMACOLOGY 75:701-709(2015).

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