Recombinant Human TP53 (Y220C) Protein, Myc/DDK-tagged
Cat.No. : | TP53-4893H |
Product Overview : | Purified recombinant protein of human tumor protein P53 (TP53), transcript variant 1, mutant (Y220C), with a C-Myc/DDK tag was expressed in HEK293 cells |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons from identical transcript variants (PMIDs: 12032546, 20937277). |
Source : | HEK293T |
Species : | Human |
Tag : | Myc/DDK |
Molecular Mass : | 43.6 kDa |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade. |
Concentration : | >50 μg/mL as determined by microplate BCA method |
Storage Buffer : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol |
Gene Name : | TP53 tumor protein p53 [ Homo sapiens (human) ] |
Official Symbol : | TP53 |
Synonyms : | TP53; tumor protein p53; P53; BCC7; LFS1; BMFS5; TRP53; cellular tumor antigen p53; antigen NY-CO-13; mutant tumor protein 53; p53 tumor suppressor; phosphoprotein p53; transformation-related protein 53; tumor protein 53; tumor supressor p53 |
Gene ID : | 7157 |
mRNA Refseq : | NM_000546 |
Protein Refseq : | NP_000537 |
MIM : | 191170 |
UniProt ID : | P04637 |
Products Types
◆ Recombinant Protein | ||
TP53-2772H | Recombinant Human TP53 Protein, His-tagged | +Inquiry |
TP53-5887R | Recombinant Rat TP53 Protein, His (Fc)-Avi-tagged | +Inquiry |
TP53-983H | Recombinant Human TP53 Protein, His-tagged | +Inquiry |
TP53-2773H | Recombinant Human TP53 Protein, His-tagged | +Inquiry |
TP53-2235H | Recombinant Human TP53 Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
TP53-860HCL | Recombinant Human TP53 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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