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Official Full Name tumor protein p53 binding protein 1
Background May have a role in checkpoint signaling during mitosis. Enhances TP53-mediated transcriptional activation. Plays a role in the response to DNA damage.
Synonyms TP53BP1; tumor protein p53 binding protein 1; p202; 53BP1; tumor suppressor p53-binding protein 1; p53BP1; p53-binding protein 1; tumor protein 53-binding protein, 1; tumor protein p53-binding protein, 1;
    • Species :
    • Human
    • Zebrafish
    • Source :
    • E.coli
    • HEK293
    • HEK293T
    • Mammalian Cell
    • Tag :
    • GST
    • His
    • Myc/DDK
    • Myc
    • DDK
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human TP53BP1-5803H Recombinant Human TP53BP1 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Human TP53BP1-15H Recombinant Human TP53BP1, GST-tagged E.coli GST
    Human TP53BP1-2302H Recombinant Human TP53BP1 Protein, MYC/DDK-tagged HEK293 Myc/DDK
    Human TP53BP1-26025TH Recombinant Human TP53BP1, His-tagged E.coli His
    Human TP53BP1-641H Recombinant Human TP53BP1 Protein, His-tagged E.coli His
    Zebrafish TP53BP1-5029Z Recombinant Zebrafish TP53BP1 Mammalian Cell His

    tp53bp1 involved in several pathways and played different roles in them. We selected most pathways tp53bp1 participated on our site, such as Cell Cycle, Cell Cycle Checkpoints, DNA Double Strand Break Response, which may be useful for your reference. Also, other proteins which involved in the same pathway with tp53bp1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Cell Cycle HIST2H3C; RAD9A; GMNN; CCND2; CCP110; CDKN2D; ATM; FZR1; ORC6L; NUMA1
    Cell Cycle Checkpoints CDKN1B; HIST3H2BB; HUS1; TP53BP1; RAD1; UBE2V2; BABAM1; HIST4H4; UIMC1; BRCC3
    DNA Double Strand Break Response BARD1; CHEK2; EYA3; UBE2V2; EYA4; BAZ1B; BABAM1; UIMC1; EYA2; TP53BP1
    DNA Double-Strand Break Repair KDM4B; TP53BP1; TDP2B; CHEK1; PPP4R2A; UBE2V2; EYA3; RBBP8; HUS1; POLD3
    DNA Repair RAD18; GPS1; RNF168; EME2; KIAA0146; EYA2; INO80; POLD3; CHD1L; EYA3
    G2/M Checkpoints BARD1; BRE; HUS1; BABAM1; RNF168; TP53BP1; RAD9B; FAM175A; UIMC1; RAD9
    G2/M DNA damage checkpoint RNF168; TP53BP1; BRE; BARD1; FAM175A; UIMC1; BRCC3; THRSP; BABAM1
    HDR through Homologous Recombination (HR) or Single Strand Annealing (SSA) EME2; PPP4CB; PPP4R2A; THRSP; RAD1; RNF4; RBBP8; TOPBP1; UIMC1; TIPIN

    tp53bp1 has several biochemical functions, for example, RNA polymerase II activating transcription factor binding, RNA polymerase II transcription cofactor activity, damaged DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by tp53bp1 itself. We selected most functions tp53bp1 had, and list some proteins which have the same functions with tp53bp1. You can find most of the proteins on our site.

    Function Related Protein
    RNA polymerase II activating transcription factor binding NCOR1; PITX2; EGR2; TBX3; NFE2L2; CREB1; SMAD3; BHLHE40; RB1; CREBBP
    RNA polymerase II transcription cofactor activity MED13; TP53BP1; MED13L; MED31; MED20; MED11; MED21; MDT-19; MED19; MED18
    damaged DNA binding BRCA1; XRCC5; RAD1; CREBBP; TRP53; POLD1; REV1; RAD23A; NEIL2; ERCC1
    methylated histone binding CBX5; CDYL2; MSL3; PHF8; ING2; CBX7; SUZ12; LOXL2; PHF19; PHF2
    p53 binding MAPKAPK5; ANKRD1; NUAK1; CHD8; ZNF346; ZMAT4; SMYD2; RNF20; CDKN2A; RFFL
    protein binding SNW1; CDCA4; MTAP1B; KRTAP4-2; HIST1H2AM; FAM90A1; MUL1; FAM134B; TTPA; SLC25A23
    telomeric DNA binding HNRNPD; TERT; TEN1; SMG6; PIF1; TP53BP1; NCL; CDAN1; TERF1; OBFC1

    tp53bp1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with tp53bp1 here. Most of them are supplied by our site. Hope this information will be useful for your research of tp53bp1.


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