|Official Full Name||tumor protein p53 binding protein, 2|
|Background||This gene encodes a member of the ASPP (apoptosis-stimulating protein of p53) family of p53 interacting proteins. The protein contains four ankyrin repeats and an SH3 domain involved in protein-protein interactions. It is localized to the perinuclear region of the cytoplasm, and regulates apoptosis and cell growth through interactions with other regulatory molecules including members of the p53 family. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]|
|Synonyms||TP53BP2; tumor protein p53 binding protein, 2; BBP; 53BP2; ASPP2; P53BP2; PPP1R13A; apoptosis-stimulating of p53 protein 2; BCL2-binding protein; renal carcinoma antigen NY-REN-51; tumor suppressor p53-binding protein 2; apoptosis-stimulating protein of p53, 2;|
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tp53bp2 involved in several pathways and played different roles in them. We selected most pathways tp53bp2 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with tp53bp2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
tp53bp2 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by tp53bp2 itself. We selected most functions tp53bp2 had, and list some proteins which have the same functions with tp53bp2. You can find most of the proteins on our site.
tp53bp2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with tp53bp2 here. Most of them are supplied by our site. Hope this information will be useful for your research of tp53bp2.