Recombinant Human UBA7 Protein, Myc/DDK-tagged, C13 and N15-labeled
Cat.No. : | UBA7-6310H |
Product Overview : | UBA7 MS Standard C13 and N15-labeled recombinant protein (NP_003326) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells. |
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Description : | The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E1 ubiquitin-activating enzyme family. The encoded enzyme is a retinoid target that triggers promyelocytic leukemia (PML)/retinoic acid receptor alpha (RARalpha) degradation and apoptosis in acute promyelocytic leukemia, where it is involved in the conjugation of the ubiquitin-like interferon-stimulated gene 15 protein. |
Source : | HEK293 |
Species : | Human |
Tag : | Myc/DDK |
Molecular Mass : | 111.7 kDa |
AA Sequence : | MDALDASKLLDEELYSRQLYVLGSP AMQRIQGARVLVSGLQGLGAEVAKN LVLMGVGSLTLHDPHPTCWSDLAAQ FLLSEQDLERSRAEASQELLAQLNR AVQVVVHTGDITEDLLLDFQVVVLT AAKLEEQLKVGTLCHKHGVCFLAAD TRGLVGQLFCDFGEDFTVQDPTEAE PLTAAIQHISQGSPGILTLRKGANT HYFRDGDLVTFSGIEGMVELNDCDP RSIHVREDGSLEIGDTTTFSRYLRG GAITEVKRPKTVRHKSLDTALLQPH VVAQSSQEVHHAHCLHQAFCALHKF QHLHGRPPQPWDPVDAETVVGLARD LEPLKRTEEEPLEEPLDEALVRTVA LSSAGVLSPMVAMLGAVAAQEVLKA ISRKFMPLDQWLYFDALDCLPEDGE LLPSPEDCALRGSRYDGQIAVFGAG FQEKLRRQHYLLVGAGAIGCELLKV FALVGLGAGNSGGLTVVDMDHIERS NLSRQFLFRSQDVGRPKAEVAAAAA RGLNPDLQVIPLTYPLDPTTEHIYG DNFFSRVDGVAAALDSFQARRYVAA RCTHYLKPLLEAGTSGTWGSATVFM PHVTEAYRAPASAAASEDAPYPVCT VRYFPSTAEHTLQWARHEFEELFRL SAETINHHQQAHTSLADMDEPQTLT LLKPVLGVLRVRPQNWQDCVAWALG HWKLCFHYGIKQLLRHFPPNKVLED GTPFWSGPKQCPQPLEFDTNQDTHL LYVLAAANLYAQMHGLPGSQDWTAL RELLKLLPQPDPQQMAPIFASNLEL ASASAEFGPEQQKELNKALEVWSVG PPLKPLMFEKDDDSNFHVDFVVAAA SLRCQNYGIPPVNRAQSKRIVGQII PAIATTTAAVAGLLGLELYKVVSGP RPRSAFRHSYLHLAENYLIRYMPFA PAIQTFHHLKWTSWDRLKVPAGQPE RTLESLLAHLQEQHGLRVRILLHGS ALLYAAGWSPEKQAQHLPLRVTELV QQLTGQAPAPGQRVLVLELSCEGDD EDTAFPPLHYELTRTRPLEQKLISE EDLAANDILDYKDDDDKV |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 3 months from receipt of products under proper storage and handling conditions. |
Storage : | Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
Concentration : | 50 μg/mL as determined by BCA |
Storage Buffer : | 100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
Gene Name : | UBA7 ubiquitin-like modifier activating enzyme 7 [ Homo sapiens (human) ] |
Official Symbol : | UBA7 |
Synonyms : | UBA7; ubiquitin-like modifier activating enzyme 7; UBE1L, ubiquitin activating enzyme E1 like; ubiquitin-like modifier-activating enzyme 7; D8; UBA1; ubiquitin activating enzyme E1 homolog B (yeast); UBA1B; ubiquitin activating enzyme E1; UBE2; ubiquitin-activating enzyme 7; ubiquitin-activating enzyme-2; UBA7, ubiquitin-activating enzyme E1; ubiquitin-activating enzyme E1 homolog; UBA1, ubiquitin-activating enzyme E1 homolog B; ubiquitin-activating enzyme E1-related protein; UBE1L; MGC12713; |
Gene ID : | 7318 |
mRNA Refseq : | NM_003335 |
Protein Refseq : | NP_003326 |
MIM : | 191325 |
UniProt ID : | P41226 |
Products Types
◆ Recombinant Protein | ||
UBA7-0051H | Recombinant Human UBA7 Protein (D2-L1012), His/Strep tagged | +Inquiry |
UBA7-0050H | Recombinant Human UBA7 Protein (D2-L1012), Tag Free | +Inquiry |
Uba7-6770M | Recombinant Mouse Uba7 Protein, Myc/DDK-tagged | +Inquiry |
UBA7-2291H | Recombinant Human UBA7 Protein, His (Fc)-Avi-tagged | +Inquiry |
UBA7-833H | Recombinant Human UBA7, GST-tagged | +Inquiry |
◆ Lysates | ||
UBA7-601HCL | Recombinant Human UBA7 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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