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Official Full Name ubiquitin-like modifier activating enzyme 1
Background Ubiquitin-activating enzymes, also known as E1 enzymes, catalyze the first step in the ubiquitination reaction, which targets a protein for degradation via a proteasome. This covalent attachment of ubiquitin or ubiquitin-like proteins to targeted proteins is a major mechanism for regulating protein function in eukaryotic organisms. Many processes such as cell division, immune responses and embryonic development are also regulated by post-transcriptional modification by ubiquitin and ubiquitin-like proteins.
Synonyms UBA1; ubiquitin-like modifier activating enzyme 1; A1S9; A1ST; GXP1; UBE1; A1S9T; AMCX1; POC20; SMAX2; UBA1A; UBE1X; MGC4781; ubiquitin-like modifier-activating enzyme 1
    • Species :
    • Human
    • Mouse
    • Rat
    • Zebrafish
    • Source :
    • E.coli
    • HEK293
    • HEK293T
    • Insect Cell
    • Insect Cells
    • Mammalian Cell
    • Sf9 Insect Cell
    • Tag :
    • C-Myc/DDK
    • Flag
    • GST
    • His
    • Myc/DDK
    • Myc
    • DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human UBA1-105H Recombinant Human UBA1 E.coli N/A
    Human UBA1-212H Recombinant Human UBA1 Protein, MYC/DDK-tagged HEK293 Myc/DDK
    Human UBA1-264H Recombinant Human UBA1 Protein, MYC/DDK-tagged, C13 and N15-labeled HEK293 C-Myc/DDK
    Human UBA1-337H Recombinant Human UBA1 Protein, His-tagged Insect Cells His
    Human UBA1-420HCL Recombinant Human UBA1 cell lysate Insect Cell N/A
    Human UBA1-476H Recombinant Human UBA1, GST-tagged Sf9 Insect Cell Flag
    Human UBA1-58H Recombinant Human Ubiquitin-like Modifier Activating Enzyme 1 Sf9 Insect Cell N/A
    Human UBA1-641H Recombinant Human UBA1 Protein, GST-tagged, Active Insect Cell GST
    Human UBA1-7333H Recombinant Human UBA1, His & GST tagged Insect Cell His/GST
    Human UBA1-832H Recombinant Human UBA1, GST-tagged Sf9 Insect Cell GST
    Mouse Uba1-6764M Recombinant Mouse Uba1 Protein, Myc/DDK-tagged HEK293T Myc/DDK
    Rat UBA1-6385R Recombinant Rat UBA1 Protein Mammalian Cell His
    Zebrafish UBA1-12294Z Recombinant Zebrafish UBA1 Mammalian Cell His

    uba1 involved in several pathways and played different roles in them. We selected most pathways uba1 participated on our site, such as Ubiquitin mediated proteolysis, Parkinsons disease, which may be useful for your reference. Also, other proteins which involved in the same pathway with uba1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Ubiquitin mediated proteolysis CBLB; UBE2S; CUL2; UBE4A; NHLRC1; UBE2A; RFWD2; MGRN1B; WWP2; SMURF2
    Parkinsons disease NDUFA6; ATP5H; NDUFS5; MT-ATP6; SLC18A1; SLC25A5; CYCS; GNAI1; COX8C; DRD1A

    uba1 has several biochemical functions, for example, ATP binding, poly(A) RNA binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by uba1 itself. We selected most functions uba1 had, and list some proteins which have the same functions with uba1. You can find most of the proteins on our site.

    Function Related Protein
    poly(A) RNA binding EIF3G; AHNAK; DHX9; HMGB2; SNRNP70; AATF; HARS2; PCBP4; FASTKD2; RPS7
    protein binding VBP1; TBC1D2; HTRA3; TMED1; POLDIP2; SERPINF2; APBB1IP; ARHGEF6; ALG13; PRKACB
    ubiquitin activating enzyme activity UBA7; UBA6; UBE1Y1; SAE1; ATG7; UBA1
    ubiquitin-protein transferase activity FBXW11; PEX2; BIRC3; FBXL5; NSMCE1; LNX1; TRAF4A; TRAF4; ZNRF3; BIRC5A

    uba1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with uba1 here. Most of them are supplied by our site. Hope this information will be useful for your research of uba1.

    GAN; BIRC3; MAGEC2; q76353_9hiv1; CCDC69; YAF2; HIP1; RIOK3; HGS; MDM4; RNF13; HIP1R; DNAJB6

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