Recombinant Mouse Arhgap15 Protein, Myc/DDK-tagged

• Cat.No.: Arhgap15-1679M
• Product Overview: Purified recombinant protein of mouse full-length Rho GTPase activating protein 15 (cDNA clone MGC:41314 IMAGE:3468639), complete cds, with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: The protein encoded by this gene is a RAC GTPase-activating protein that is regulated through its PH domain and by recruitment to the membrane. The protein accelerates hydrolysis of guanosine triphosphate to guanosine diphosphate to repress Rac activity. Knock-out of Arhgap15 function demonstrates that this gene is required to regulate multiple functions in macrophages and neutrophils. Alternative splicing results in multiple transcript variants encoding different isoforms.
• Source: HEK293T
• Species: Mouse
• Tag: Myc/DDK
• Molecular Mass: 51.8 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Arhgap15 Rho GTPase activating protein 15 [ Mus musculus (house mouse) ]
• Official Symbol: Arhgap15
• Synonyms: Arhgap15; Rho GTPase activating protein 15; 5830480G12Rik; rho GTPase-activating protein 15; rho-type GTPase-activating protein 15
• Gene ID: 76117
• mRNA Refseq: NM_153820
• Protein Refseq: NP_722542
• UniProt ID: Q811M1