ARHGAP33
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Official Full Name
Rho GTPase activating protein 33 -
Overview
This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. Alternative splice variants encoding different isoforms have been identified in this gene. -
Synonyms
ARHGAP33;Rho GTPase activating protein 33;SNX26, sorting nexin 26;rho GTPase-activating protein 33;FLJ39019;TCGAP;sorting nexin 26;sorting nexin-26;tc10/CDC42 GTPase-activating protein;rho-type GTPase-activating protein 33;neurite outgrowth mul
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| ARHGAP33-1872M | Recombinant Mouse ARHGAP33 Protein | Mammalian Cells | Mouse | His |
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| ARHGAP33-681M | Recombinant Mouse ARHGAP33 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | Avi&Fc&His |
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| ARHGAP33-681M-B | Recombinant Mouse ARHGAP33 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
ARHGAP33 involved in several pathways and played different roles in them. We selected most pathways ARHGAP33 participated on our site, such as Insulin Signaling,Rho GTPase cycle,Signal Transduction, which may be useful for your reference. Also, other proteins which involved in the same pathway with ARHGAP33 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| cyclic AMP biosynthesis | PDC,RAP1GAP2,GARNL3,RALGAPA1,DOCK8,RIC8 |
| Signaling by Rho GTPases | OPHN1,RHOT1,CHN1,FAM13A,MKL1B,RHOUA,ARHGAP8,RHOF,RHOV,ARHGAP25 |
| Insulin Signaling | GRB14,GSK3AB,MAPK6,SNAP25A,MYO1C,STXBP3,REG1A,INPP4AA,MAPK4,RRAD |
| Rho GTPase cycle | FGD4A,RHOJ,ARHGAP29B,TAGAPA,ARHGAP6,ARHGAP10,AKAP13,CHN2,CHN1,ARHGAP12B |
| Signal Transduction | QRFPR,FAM105B,PRLRB,MDKB,MKL1,GDI2,ABHD6B,PRC1B,RAB6A,GPR161 |
| XPodNet - protein-protein interactions in the podocyte expanded by STRING | LIMS2,CARF,PKD1,RAVER1,CDC42EP5,ATP9A,FLII,SNTB1,GAB3,KCP |
Protein Function
ARHGAP33 has several biochemical functions, for example, GTPase activator activity,phosphatidylinositol binding,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ARHGAP33 itself. We selected most functions ARHGAP33 had, and list some proteins which have the same functions with ARHGAP33. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| GTPase activator activity | TBC1D24,LLGL2,STARD8,RGS5B,ARHGAP4,SGSM3,ARHGEF15,ACAP3B,SMAP1,ARHGAP23 |
| phosphatidylinositol binding | TULP2,SNX7,SNX9B,SNX2,NOXO1A,SNX1,TULP4,FCHO2,SLC12A9,SNX27B |
| protein binding | SPTSSB,CHDH,KIF18B,PTK2,MYH7B,EXOSC5,CD70,LDHB,NINJ1,CBX7 |
Interacting Protein
ARHGAP33 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ARHGAP33 here. Most of them are supplied by our site. Hope this information will be useful for your research of ARHGAP33.
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References
- Jarius, S; Wandinger, KP; et al. A new Purkinje cell antibody (anti-Ca) associated with subacute cerebellar ataxia: immunological characterization. JOURNAL OF NEUROINFLAMMATION 7:-(2010).
