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Official Full Name Rho GTPase activating protein 5
Background Rho GTPase activating protein 5 negatively regulates RHO GTPases, a family which may mediate cytoskeleton changes by stimulating the hydrolysis of bound GTP. Two transcript variants encoding different isoforms have been found for this gene.
Synonyms ARHGAP5; Rho GTPase activating protein 5; GFI2, growth factor independent 2; rho GTPase-activating protein 5; p190 B; p190BRhoGAP; RhoGAP5; ARHGAP 5; p190 RhoGAP; RhoGAP 5; RhoGAP; p105 RhoGAP; OTTHUMP00000244094; OTTHUMP00000244095; OTTHUMP00000244097; OTTHUMP00000244099; growth factor independent 2; p100 RasGAP-associated p105 protein; rho-type GTPase-activating protein 5; GFI2; p190-B
    • Species :
    • Human
    • Rhesus Macaque
    • Source :
    • HEK293
    • Mammalian Cell
    • Tag :
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human ARHGAP5-8737HCL Recombinant Human ARHGAP5 293 Cell Lysate HEK293 N/A
    Rhesus Macaque ARHGAP5-393R Recombinant Rhesus monkey ARHGAP5 Protein, His-tagged Mammalian Cell His

    arhgap5 involved in several pathways and played different roles in them. We selected most pathways arhgap5 participated on our site, such as Focal adhesion, Leukocyte transendothelial migration, which may be useful for your reference. Also, other proteins which involved in the same pathway with arhgap5 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Focal adhesion MYL9A; ITGA6; DIAP1; ITGB7; SOS1; PDGFC; PDGFA; CAV1; SRMS; HRAS
    Leukocyte transendothelial migration CXCR4; PIK3CD; TXK; MAPK12; RAC1; PIK3CA; GNAI1; CLDN16; PTK2B; VCL

    arhgap5 has several biochemical functions, for example, GTP binding, GTPase activator activity, GTPase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by arhgap5 itself. We selected most functions arhgap5 had, and list some proteins which have the same functions with arhgap5. You can find most of the proteins on our site.

    Function Related Protein
    GTPase activator activity TBC1D14; TBC1D3C; ARHGAP17; ARHGAP1; CDC42EP1; SIPA1L2; BAI3; SMAP2; SRGAP2A; ARHGDIG
    GTPase activity SRPR; RAC1; DIRAS3; GNA15.4; EEF1A1L1; EFTUD1; ARF5; RAN; GBP4; RAB9B
    SH2 domain binding DAG1; SKAP1; SYP; JAK2; SQSTM1; LAX1; LAT2; KHDRBS2; NLK; PAG1
    protein binding DIAP1; PLCG1; LIG3; C8orf48; ABCF1; ZNF346; C16orf45; CTSB; LUM; UBQLN4

    arhgap5 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with arhgap5 here. Most of them are supplied by our site. Hope this information will be useful for your research of arhgap5.

    Rnd3; SMURF2

    Jarius, S; Scharf, M; et al. Antibodies to the inositol 1,4,5-trisphosphate receptor type 1 (ITPR1) in cerebellar ataxia. Journal of Neuroinflammation 11:-(2014).
    Zhang, QP; Zhang, HY; et al. srGAP3 promotes neurite outgrowth of dorsal root ganglion neurons by inactivating RAC1. ASIAN PACIFIC JOURNAL OF TROPICAL MEDICINE 7:630-638(2014).

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