Recombinant Human POLR2C, His-tagged

• Cat.No.: POLR2C-1841H
• Product Overview: Recombinant Human POLR2C protein, fused to His-tag, was expressed in E.coli and purified by Ni-sepharose.

Specification

• Source: E.coli
• Species: Human
• Tag: His
• Protein length: 58-275aa
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol.

Gene Information

• Gene Name: POLR2C polymerase (RNA) II (DNA directed) polypeptide C, 33kDa [ Homo sapiens ]
• Official Symbol: POLR2C
• Synonyms: POLR2C; polymerase (RNA) II (DNA directed) polypeptide C, 33kDa; polymerase (RNA) II (DNA directed) polypeptide C (33kD); DNA-directed RNA polymerase II subunit RPB3; RNA polymerase II subunit 3; RPB3; RPB33; RNA polymerase II subunit B3; DNA-directed RNA polymerase II subunit C; DNA-directed RNA polymerase II 33 kDa polypeptide; RPB31; hRPB33; hsRPB3
• Gene ID: 5432
• mRNA Refseq: NM_032940
• Protein Refseq: NP_116558
• MIM: 180663
• UniProt ID: P19387
• Chromosome Location: 16q13-q21
• Pathway: Abortive elongation of HIV-1 transcript in the absence of Tat, organism-specific biosystem; DNA Repair, organism-specific biosystem; Disease, organism-specific biosystem; Dual incision reaction in TC-NER, organism-specific biosystem; Eukaryotic Transcription Initiation, organism-specific biosystem; Formation of HIV-1 elongation complex containing HIV-1 Tat, organism-specific biosystem; Formation of HIV-1 elongation complex in the absence of HIV-1 Tat, organism-specific biosystem
• Function: DNA binding; DNA-directed RNA polymerase activity; protein dimerization activity; contributes_to protein kinase activity