POLR3C
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Official Full Name
polymerase (RNA) III (DNA directed) polypeptide C (62kD)
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Overview
DNA-directed RNA polymerase III subunit RPC3 is an enzyme that in humans is encoded by the POLR3C gene. POLR3C has been shown to interact with GTF3C4. -
Synonyms
POLR3C; polymerase (RNA) III (DNA directed) polypeptide C (62kD); DNA-directed RNA polymerase III subunit RPC3; RPC3; RPC62; DNA directed III 62 kDa polypeptide; DNA-directed RNA polymerase III subunit C; RNA polymerase C subunit 3; RNA polymerase III 62 kDa subunit; RNA polymerase III C62 subunit; RNA polymerase III subunit C3; RPC3_HUMAN; DNA-directed III 62 kDa polypeptide;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Human
- Mouse
- Rat
- Zebrafish
- E.coli
- HEK293
- HEK293T
- Mammalian Cell
- His
- His (Fc)
- Avi
- SUMO
- Myc
- DDK
- N/A
- T7
| Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| Human | POLR3C-836H | Recombinant Human POLR3C, T7-tagged | E.coli | T7 |
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| Human | POLR3C-3026HCL | Recombinant Human POLR3C 293 Cell Lysate | HEK293 | N/A |
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| Human | POLR3C-829H | Recombinant Human POLR3C Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293T | Myc/DDK |
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| Human | POLR3C-4831H | Recombinant Human POLR3C protein, His-SUMO-tagged | E.coli | His-SUMO | 1-534aa |
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| Mouse | Polr3c-5004M | Recombinant Mouse Polr3c Protein, Myc/DDK-tagged | HEK293T | Myc/DDK |
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| Rat | POLR3C-4573R | Recombinant Rat POLR3C Protein | Mammalian Cell | His |
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| Rat | POLR3C-4233R | Recombinant Rat POLR3C Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi |
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| Rat | POLR3C-4233R-B | Recombinant Rat POLR3C Protein Pre-coupled Magnetic Beads | HEK293 |
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| Zebrafish | POLR3C-10572Z | Recombinant Zebrafish POLR3C | Mammalian Cell | His |
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- Involved Pathway
- Protein Function
- Interacting Protein
POLR3C involved in several pathways and played different roles in them. We selected most pathways POLR3C participated on our site, such as Cytosolic DNA-sensing pathway, Cytosolic sensors of pathogen-associated DNA, Epstein-Barr virus infection, which may be useful for your reference. Also, other proteins which involved in the same pathway with POLR3C were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Cytosolic DNA-sensing pathway | IL18;POLR2E;POLR2L;NFKBIAB;IFNA4;DDX58;IL6;POLR3G;IFNA6 |
| Cytosolic sensors of pathogen-associated DNA | APPA;NLRP4;CRCP;POLR3H;POLR3G;NLRP4E;POLR3F;S100A12;S100B |
| Epstein-Barr virus infection | EIF2AK3;POLR3F;PLCG1;POLR3K;PRKACB;MAPK10;YWHAE;MDM2;PSMC5 |
| Gene Expression | ZNF560;ZNF157;ZNF143;LAGE3;POU2F1B;SETB;TBX5A;GTF3C5;MAPKAPK2B |
| Immune System | IRF4;SIGIRR;CRTAM;RACGAP1;DEFB4A;LILRB5;TRIM8;DYNC1H1;ACTR1A |
| Innate Immune System | DDOST;NOD1;FCN1;SIRPB1;IFI16;PCBP2;DEFA1;DEFA5;SIGLEC15 |
| Metabolic pathways | NT5C2;NSDHL;DPM2;IPPK;SLC33A1;HSD11B1;ITPA;TPI1;FBP1A |
| Purine metabolism | NME7;GUCY2E;CECR1A;POLR2F;PDE6H;NME1-NME2;NT5M;PRPS1L1;GUK1B |
POLR3C has several biochemical functions, for example, DNA binding, DNA-directed RNA polymerase activity, contributes_to RNA polymerase III activity. Some of the functions are cooperated with other proteins, some of the functions could acted by POLR3C itself. We selected most functions POLR3C had, and list some proteins which have the same functions with POLR3C. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| DNA binding | HMGB4;POLR1C;BANF2;ZNF180;LIG1;DNAJB6;FAM171B;HIST1H4J;MLLT10 |
| DNA-directed RNA polymerase activity | MED21;POLR3F;MED20;PRIM2;POLR2GL;POLR3A;POLR1C;RPAP1;POLR3H |
| contributes_to RNA polymerase III activity | CRCP;POLR3C;POLR3GLB;POLR3GLA;POLR3K;POLR3E;POLR1C;POLR3B;POLR3F |
| protein binding | EHD4;GNAI1;DZIP3;SHC3;EFHA1;MSI2;EIF1AD;VSNL1;C14orf104 |
POLR3C has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with POLR3C here. Most of them are supplied by our site. Hope this information will be useful for your research of POLR3C.
TNR; TRIM27; ROCK1; PNMA5; ROPN1; ssrna_ug
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