|Official Full Name||polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa|
|Background||This gene encodes a subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. The product of this gene contains four conserved cysteines characteristic of an atypical zinc-binding domain. Like its counterpart in yeast, this subunit may be shared by the other two DNA-directed RNA polymerases.|
|Synonyms||POLR2L; polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa; polymerase (RNA) II (DNA directed) polypeptide L (7.6kD); DNA-directed RNA polymerases I, II, and III subunit RPABC5; hRPB7.6; hsRPB10b; RBP10; RPABC5; RPB7.6; RPB10beta; DNA directed RNA polymerase II polypeptide L; RNA polymerase II polypeptide L; RPB10; RPB10 homolog; RNA polymerase II 7.6 kDa subunit; DNA-directed RNA polymerase III subunit L; RNA polymerases I, II, and III subunit ABC5|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
polr2l involved in several pathways and played different roles in them. We selected most pathways polr2l participated on our site, such as Purine metabolism, Pyrimidine metabolism, Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with polr2l were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
|Purine metabolism||NT5C1B-RDH14; ADSSL1; PRPS1B; POLE; POLR2F; POLR1A; URAH; NT5E; ADSL; NT5C2A|
|Pyrimidine metabolism||TXNRD2; TK1; POLR2H; POLR3GLB; NT5C2; UCKL1; POLR3A; POLE2; PRIM2; POLD2|
|Metabolic pathways||NDUFB4; ITPA; MAN1B1; LTA4H; HMGCR; Atp5k; ABP1; ALDH3A1; PIP5K1A; SMPD2|
|RNA polymerase||POLR2C; POLR2I; TWISTNB; POLR1D; POLR3E; POLR2B; POLR1B; POLR1A; POLR2F; POLR2J|
|Cytosolic DNA-sensing pathway||CCL4; IL6; TBK1; POLR3D; CCL4L1; IL18; IFNA7; RIPK1L; RIPK1; IFNA17|
|Huntingtons disease||COX7B; DCTN2; NDUFS3; NDUFV2; PLCB1; NDUFS5; COX6A2; ATP5H; HTT; COX8C|
|Epstein-Barr virus infection||H2-Q10; HDAC4; SFPI1; AKT2; IRAK1; HLA-B; POLR1C; POLR2G; FCER2; POLR2D|
polr2l has several biochemical functions, for example, DNA binding, DNA-directed RNA polymerase activity, contributes_to RNA polymerase I activity. Some of the functions are cooperated with other proteins, some of the functions could acted by polr2l itself. We selected most functions polr2l had, and list some proteins which have the same functions with polr2l. You can find most of the proteins on our site.
|DNA binding||AHRRA; ZBTB26; POU5F3; TOP1; DMRT2; MYBL2B; THAP4; FUZ; ZFP746; RORAB|
|DNA-directed RNA polymerase activity||POLR2GL; MED21; POLR3A; POLR3H; POLR2A; POLR2E; POLR3C; POLR2L; POLR3B; POLR1C|
|contributes_to RNA polymerase I activity||POLR2H; POLR2E; POLR2K; POLR2L; POLR1A; POLR1D; POLR1C; POLR1E; TWISTNB; ZNRD1|
|contributes_to RNA polymerase II activity||POLR2L; POLR2F; POLR2EB; POLR2A; POLR2J; POLR2J2; POLR2H; POLR2J3; POLR2C; POLR2K|
|contributes_to RNA polymerase III activity||CRCP; POLR3C; POLR2E; POLR3GLA; POLR1C; POLR2EB; POLR3H; POLR2H; POLR3B; POLR3GL|
|protein binding||CISD2; MAPKAPK2; TH1L; METTL21C; ALDOB; IGF2BP1; PACSIN2; BMF; VTI1B; DCTN4|
|zinc ion binding||LNX2A; ZFYVE19; LMCD1; PCGF5A; PRKCBB; PGLYRP2; RUFY1; HLTF; EEA1; MTF2|
polr2l has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with polr2l here. Most of them are supplied by our site. Hope this information will be useful for your research of polr2l.
ZBTB14; COIL; REL; TP53BP2; PHC2; BANP; L3MBTL3