polr2l

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polr2l

Official Full Name polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa
Background This gene encodes a subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. The product of this gene contains four conserved cysteines characteristic of an atypical zinc-binding domain. Like its counterpart in yeast, this subunit may be shared by the other two DNA-directed RNA polymerases.
Synonyms POLR2L; polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa; polymerase (RNA) II (DNA directed) polypeptide L (7.6kD); DNA-directed RNA polymerases I, II, and III subunit RPABC5; hRPB7.6; hsRPB10b; RBP10; RPABC5; RPB7.6; RPB10beta; DNA directed RNA polymerase II polypeptide L; RNA polymerase II polypeptide L; RPB10; RPB10 homolog; RNA polymerase II 7.6 kDa subunit; DNA-directed RNA polymerase III subunit L; RNA polymerases I, II, and III subunit ABC5
    • Species :
    • Chicken
    • Human
    • Mouse
    • Rhesus Macaque
    • Zebrafish
    • Source :
    • E.coli
    • HEK293
    • Mammalian Cell
    • Tag :
    • GST
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human POLR2L-1849H Recombinant Human POLR2L, GST-tagged E.coli GST
    Human POLR2L-3027HCL Recombinant Human POLR2L 293 Cell Lysate HEK293 N/A
    Human POLR2L-3056H Recombinant Human POLR2L, His-tagged E.coli His
    Human POLR2L-30688TH Recombinant Human POLR2L E.coli N/A
    Mouse POLR2L-13102M Recombinant Mouse POLR2L Protein Mammalian Cell His
    Rhesus Macaque POLR2L-3519R Recombinant Rhesus monkey POLR2L Protein, His-tagged Mammalian Cell His
    Chicken POLR2L-5644C Recombinant Chicken POLR2L Mammalian Cell His
    Zebrafish POLR2L-7432Z Recombinant Zebrafish POLR2L Mammalian Cell His

    polr2l involved in several pathways and played different roles in them. We selected most pathways polr2l participated on our site, such as Purine metabolism, Pyrimidine metabolism, Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with polr2l were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Purine metabolism NT5C1B-RDH14; ADSSL1; PRPS1B; POLE; POLR2F; POLR1A; URAH; NT5E; ADSL; NT5C2A
    Pyrimidine metabolism TXNRD2; TK1; POLR2H; POLR3GLB; NT5C2; UCKL1; POLR3A; POLE2; PRIM2; POLD2
    Metabolic pathways NDUFB4; ITPA; MAN1B1; LTA4H; HMGCR; Atp5k; ABP1; ALDH3A1; PIP5K1A; SMPD2
    RNA polymerase POLR2C; POLR2I; TWISTNB; POLR1D; POLR3E; POLR2B; POLR1B; POLR1A; POLR2F; POLR2J
    Cytosolic DNA-sensing pathway CCL4; IL6; TBK1; POLR3D; CCL4L1; IL18; IFNA7; RIPK1L; RIPK1; IFNA17
    Huntingtons disease COX7B; DCTN2; NDUFS3; NDUFV2; PLCB1; NDUFS5; COX6A2; ATP5H; HTT; COX8C
    Epstein-Barr virus infection H2-Q10; HDAC4; SFPI1; AKT2; IRAK1; HLA-B; POLR1C; POLR2G; FCER2; POLR2D

    polr2l has several biochemical functions, for example, DNA binding, DNA-directed RNA polymerase activity, contributes_to RNA polymerase I activity. Some of the functions are cooperated with other proteins, some of the functions could acted by polr2l itself. We selected most functions polr2l had, and list some proteins which have the same functions with polr2l. You can find most of the proteins on our site.

    Function Related Protein
    DNA binding AHRRA; ZBTB26; POU5F3; TOP1; DMRT2; MYBL2B; THAP4; FUZ; ZFP746; RORAB
    DNA-directed RNA polymerase activity POLR2GL; MED21; POLR3A; POLR3H; POLR2A; POLR2E; POLR3C; POLR2L; POLR3B; POLR1C
    contributes_to RNA polymerase I activity POLR2H; POLR2E; POLR2K; POLR2L; POLR1A; POLR1D; POLR1C; POLR1E; TWISTNB; ZNRD1
    contributes_to RNA polymerase II activity POLR2L; POLR2F; POLR2EB; POLR2A; POLR2J; POLR2J2; POLR2H; POLR2J3; POLR2C; POLR2K
    contributes_to RNA polymerase III activity CRCP; POLR3C; POLR2E; POLR3GLA; POLR1C; POLR2EB; POLR3H; POLR2H; POLR3B; POLR3GL
    protein binding CISD2; MAPKAPK2; TH1L; METTL21C; ALDOB; IGF2BP1; PACSIN2; BMF; VTI1B; DCTN4
    zinc ion binding LNX2A; ZFYVE19; LMCD1; PCGF5A; PRKCBB; PGLYRP2; RUFY1; HLTF; EEA1; MTF2

    polr2l has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with polr2l here. Most of them are supplied by our site. Hope this information will be useful for your research of polr2l.

    ZBTB14; COIL; REL; TP53BP2; PHC2; BANP; L3MBTL3

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