POLR2H

  • Official Full Name

    polymerase (RNA) II (DNA directed) polypeptide H

  • Overview

    This gene encodes one of the essential subunits of RNA polymerase II that is shared by the other two eukaryotic DNA-directed RNA polymerases, I and III.

  • Synonyms

    POLR2H;polymerase (RNA) II (DNA directed) polypeptide H;DNA-directed RNA polymerases I, II, and III subunit RPABC3;RPB8;and III 17.1 kDa polypeptide;and III subunit ABC3;II;DNA-directed RNA polymerase II subunit H;DNA-directed RNA polymerases I;hRPB8;RNA polymerases I;RPAB3_HUMAN;RPB17;RPB8 homolog;OTTHUMP00000210505;OTTHUMP00000210507;OTTHUMP00000210508;OTTHUMP00000210509;OTTHUMP00000210511;OTTHUMP00000210512;RNA polymerases I, II,;RPABC3;hsRPB8

Recombinant Proteins

  • Mouse
  • Zebrafish
  • Chicken
  • Human
  • Cynomolgus
  • Mammalian Cells
  • E.coli
  • HEK293
  • His
  • GST
  • Non
  • DDK
  • Myc
  • Avi
  • Fc

    Involved Pathway

    POLR2H involved in several pathways and played different roles in them. We selected most pathways POLR2H participated on our site, such as Purine metabolism,Pyrimidine metabolism,Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with POLR2H were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Pyrimidine metabolism ENTPD5,NT5E,PNPT1,RRM2,NT5C1A,POLR1B,PNP5A,DUT,TWISTNB,POLR3D
    Huntingtons disease APAF1,COX6C,SP1,NDUFS2,NDUFA9,NDUFB5,Casp3,NDUFS6,NDUFA4,ATP5F1
    Epstein-Barr virus infection PIK3R3,FGR,SYK,ENTPD3,POLR3F,PIK3CD,PLCG2,HLA-G,HLA-DRB5,RBPJL
    Cytosolic DNA-sensing pathway CXCL10,POLR1C,IFNPHI3,IFNA4,POLR3F,TBK1,IKBKE,CCL4L2,IFNA2,POLR3B
    RNA polymerase POLR3B,POLR2A,POLR2L,POLR2C,POLR3GLB,POLR3K,POLR2F,POLR2J3,POLR2K,POLR3E
    Metabolic pathways ST6GALNAC1,SEPHS1,PKM,PIGL,SMPD5,NMNAT3,COQ6,ACO1,PLCB4,ADO
    Purine metabolism POLR2E,PDE6C,ENTPD5,PDE8A,PDE8B,PNP,POLR2A,POLR2C,ADKA,ENTPD6

    Protein Function

    POLR2H has several biochemical functions, for example, DNA binding,contributes_to RNA polymerase I activity,contributes_to RNA polymerase II activity. Some of the functions are cooperated with other proteins, some of the functions could acted by POLR2H itself. We selected most functions POLR2H had, and list some proteins which have the same functions with POLR2H. You can find most of the proteins on our site.

    Function Related Protein
    DNA binding TBPL2,HIST1H2BP,POLR1E,PAX1A,RARB,DOT1L,ONECUTL,LASS2,ZFAT,NKX2.4B
    contributes_to RNA polymerase III activity POLR3B,POLR2E,POLR3C,POLR3GLA,POLR3E,POLR1D,POLR2F,POLR2L,POLR2EB,POLR3GLB
    contributes_to RNA polymerase II activity POLR2L,POLR2C,POLR2B,POLR2E,POLR2EB,POLR2K,POLR2A,POLR2J,POLR2F,POLR2J2
    contributes_to RNA polymerase I activity POLR2L,ZNRD1,POLR2F,POLR2EB,POLR1C,POLR1E,POLR2K,POLR1D,POLR2E,TWISTNB

    Interacting Protein

    POLR2H has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with POLR2H here. Most of them are supplied by our site. Hope this information will be useful for your research of POLR2H.

    MED19;MED26;EIF1B;NME2;CD40;IKBKE;NFKBIB;TRAF6;ubiG;ssdna_dtdg

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