POLR2H

  • Official Full Name

    polymerase (RNA) II (DNA directed) polypeptide H

  • Overview

    This gene encodes one of the essential subunits of RNA polymerase II that is shared by the other two eukaryotic DNA-directed RNA polymerases, I and III.

  • Synonyms

    POLR2H;polymerase (RNA) II (DNA directed) polypeptide H;DNA-directed RNA polymerases I, II, and III subunit RPABC3;RPB8;and III 17.1 kDa polypeptide;and III subunit ABC3;II;DNA-directed RNA polymerase II subunit H;DNA-directed RNA polymerases I;hRPB8;RNA polymerases I;RPAB3_HUMAN;RPB17;RPB8 homolog;OTTHUMP00000210505;OTTHUMP00000210507;OTTHUMP00000210508;OTTHUMP00000210509;OTTHUMP00000210511;OTTHUMP00000210512;RNA polymerases I, II,;RPABC3;hsRPB8

Recombinant Proteins

  • Mouse
  • Zebrafish
  • Chicken
  • Human
  • Cynomolgus
  • Mammalian Cells
  • E.coli
  • HEK293
  • His
  • GST
  • Non
  • DDK
  • Myc
  • Avi
  • Fc

    Involved Pathway

    POLR2H involved in several pathways and played different roles in them. We selected most pathways POLR2H participated on our site, such as Purine metabolism,Pyrimidine metabolism,Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with POLR2H were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Purine metabolism ADSSL1,PAPSS2B,POLE3,GMPR2,GC3,POLR2G,NME1-NME2,TM9SF1,NT5C1AA,PDE8A
    Huntingtons disease POLR2J2,GRM5,UQCRB,NDUFA3,TBP,NDUFC1,UQCRC1,NDUFB9,CREB3L3,UQCR10
    Pyrimidine metabolism ENTPD8,POLR2D,POLE2,DCK,POLA2,NT5C1A,NT5C,UPP2,NME2B.1,NME4
    RNA polymerase POLR3D,POLR1E,POLR2E,POLR2C,POLR2GL,POLR3E,POLR3A,POLR2J2,POLR3GLB,POLR2F
    Epstein-Barr virus infection LYN,HLA-DQB1,POLR3GL,MAP3K14,ENTPD8,POLR2D,Fcer2a,DDX58,PTMA,NEDD4
    Cytosolic DNA-sensing pathway IFN-a,IFNA14,MAVS,IRF7,POLR3H,IFNA5,POLR1C,POLR3G,ADAR,IKBKG
    Metabolic pathways CYP8B1,HPSE2,DNMT4,AKR1A1A,SPTLC2B,MGAT5B,GALNT2,BCO1,ACSL5,PIGX

    Protein Function

    POLR2H has several biochemical functions, for example, DNA binding,contributes_to RNA polymerase I activity,contributes_to RNA polymerase II activity. Some of the functions are cooperated with other proteins, some of the functions could acted by POLR2H itself. We selected most functions POLR2H had, and list some proteins which have the same functions with POLR2H. You can find most of the proteins on our site.

    Function Related Protein
    DNA binding E2F1,SIX6B,TCEB3C,ZFP36L3,PHC1,HOXD10A,LEMD3,TAF9,ASCL4,VED
    contributes_to RNA polymerase I activity POLR1D,POLR2L,POLR2K,POLR1A,POLR1E,TWISTNB,POLR2F,ZNRD1,POLR2EB,POLR1C
    contributes_to RNA polymerase III activity POLR3H,POLR3C,POLR3B,POLR2EB,POLR3GLB,POLR1C,POLR1D,POLR3GL,POLR3GLA,POLR3K
    contributes_to RNA polymerase II activity POLR2A,POLR2C,POLR2EB,POLR2B,POLR2J3,POLR2K,POLR2J2,POLR2J,POLR2L,POLR2F

    Interacting Protein

    POLR2H has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with POLR2H here. Most of them are supplied by our site. Hope this information will be useful for your research of POLR2H.

    MED19;MED26;EIF1B;NME2;CD40;IKBKE;NFKBIB;TRAF6;ubiG;ssdna_dtdg

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