POLR2H
-
Official Full Name
polymerase (RNA) II (DNA directed) polypeptide H -
Overview
This gene encodes one of the essential subunits of RNA polymerase II that is shared by the other two eukaryotic DNA-directed RNA polymerases, I and III. -
Synonyms
POLR2H;polymerase (RNA) II (DNA directed) polypeptide H;DNA-directed RNA polymerases I, II, and III subunit RPABC3;RPB8;and III 17.1 kDa polypeptide;and III subunit ABC3;II;DNA-directed RNA polymerase II subunit H;DNA-directed RNA polymerases I;hRPB8;RNA polymerases I;RPAB3_HUMAN;RPB17;RPB8 homolog;OTTHUMP00000210505;OTTHUMP00000210507;OTTHUMP00000210508;OTTHUMP00000210509;OTTHUMP00000210511;OTTHUMP00000210512;RNA polymerases I, II,;RPABC3;hsRPB8
Recombinant Proteins
- Human
- Mouse
- Zebrafish
- Chicken
- Cynomolgus
- E.coli
- Mammalian Cells
- HEK293
- GST
- His
- Non
- DDK
- Myc
- Avi
- Fc
Involved Pathway
POLR2H involved in several pathways and played different roles in them. We selected most pathways POLR2H participated on our site, such as Purine metabolism,Pyrimidine metabolism,Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with POLR2H were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Huntingtons disease | DNAHC8,CASP8,NDUFA4L2,PLCB4,COX6A1,NDUFA8,ATP5B,SLC25A4,COX6A2,DNAL1 |
| Cytosolic DNA-sensing pathway | NFKBIAA,IFN-a,POLR3G,IKBKG,POLR3H,IFNA6,IFI202B,IL1B,IFNPHI1,POLR3C |
| RNA polymerase | POLR2K,POLR1B,POLR1D,POLR2F,POLR2EB,POLR2J2,TWISTNB,POLR2B,POLR3K,POLR1E |
| Metabolic pathways | FPGS,NADSYN1,SI,MCEE,PAPSS1,CYP4F2,PIGP,B3GNT5B,AMY1B,ATP5IA |
| Purine metabolism | PRPS1L1,PRPS1,NME6,NME3,AK1,IMPDH1,NUDT16,NT5C3B,PNP,POLR3F |
| Pyrimidine metabolism | UPP2,NME4,TYMP,ENTPD5,CTPS2,UMPS,POLE3,PNP6,CMPK,UPRT |
| Epstein-Barr virus infection | PSMC5,POLR1C,SKP2,HDAC1,TBK1,HLA-DQA2,NEDD4,AKT1,PIK3CD,PSMD4 |
Protein Function
POLR2H has several biochemical functions, for example, DNA binding,contributes_to RNA polymerase I activity,contributes_to RNA polymerase II activity. Some of the functions are cooperated with other proteins, some of the functions could acted by POLR2H itself. We selected most functions POLR2H had, and list some proteins which have the same functions with POLR2H. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| contributes_to RNA polymerase III activity | POLR2E,POLR3GL,POLR3GLB,POLR2F,POLR3D,POLR3B,POLR3E,CRCP,POLR3K,POLR3C |
| contributes_to RNA polymerase II activity | POLR2EB,POLR2A,POLR2J2,POLR2B,POLR2J3,POLR2L,POLR2F,POLR2C,POLR2K,POLR2E |
| DNA binding | FANCM,ASCL5,PBX1A,NKX3.3,SP6,ISL1L,ZNF180,MTF1,EHF,RORAB |
| contributes_to RNA polymerase I activity | POLR1C,POLR2L,TWISTNB,ZNRD1,POLR2E,POLR1E,POLR1D,POLR2EB,POLR2K,POLR1A |
Interacting Protein
POLR2H has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with POLR2H here. Most of them are supplied by our site. Hope this information will be useful for your research of POLR2H.
MED19;MED26;EIF1B;NME2;CD40;IKBKE;NFKBIB;TRAF6;ubiG;ssdna_dtdg
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