"IGFBP1" Related Products

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Recombinant Human IGFBP1 protein, Active

Cat.No.: IGFBP1-29544TH
Product Overview: Recombinant Human IGFBP1 was expressed in E. coli.
Description: This gene is a member of the insulin-like growth factor binding protein (IGFBP) family and encodes a protein with an IGFBP domain and a thyroglobulin type-I domain. The protein binds both insulin-like growth factors (IGFs) I and II and circulates in the plasma. Binding of this protein prolongs the half-life of the IGFs and alters their interaction with cell surface receptors.
Source: E. coli
Species: Human
Bio-activity: The ED50, as determined by its ability to inhibit IGF-I induced proliferation of MCF-7, is < 0.5 µg/ml in the presence of 6 ng/ml of human IGF-I.
AA Sequence: MAPWQCAPCS AEKLALCPPV SASCSEVTRS AGCGCCPMCA LPLGAACGVA TARCARGLSC RALPGEQQPL HALTRGQGAC VQESDASAPH AAEAGSPESP ESTEITEEEL LDNFHLMAPS EEDHSILWDA ISTYDGSKAL HVTNIKKWKE PCRIELYRVV ESLAKAQETS GEEISKFYLP NCNKNGFYHS RQCETSMDGE AGLCWCVYPW NGKRIPGSPE IRGDPNCQIY FNVQN
Endotoxin: < 0.100 Eu/µg
Applications: Western blot; SDS-PAGE; Functional Studies
Storage: Shipped at 4 centigrade. The lyophilized protein is stable for a few weeks at room temperature. Store at -20 centigrade long term.
Reconstitution: Reconsitute to 1mg/ml with sterile water.
Gene Name: IGFBP1 insulin-like growth factor binding protein 1 [ Homo sapiens ]
Official Symbol: IGFBP1
Synonyms: IGFBP1; insulin-like growth factor binding protein 1; IBP1; insulin-like growth factor-binding protein 1; AFBP; alpha pregnancy associated endometrial globulin; amniotic fluid binding protein; binding protein 25; binding protein 26; binding protein 28; growth hormone independent binding protein; hIGFBP 1; IGF binding protein 1; IGF BP25; placental protein 12; PP12; IBP-1; IGFBP-1; binding protein-25; binding protein-26; binding protein-28; IGF-binding protein 1; growth hormone independent-binding protein; alpha-pregnancy-associated endometrial globulin; IGF-BP25; hIGFBP-1;
Gene ID: 3484
mRNA Refseq: NM_000596
Protein Refseq: NP_000587
MIM: 146730
UniProt ID: P08833
Chromosome Location: 7p13-p12
Pathway: Activation of Genes by ATF4, organism-specific biosystem; Diabetes pathways, organism-specific biosystem; Disease, organism-specific biosystem; FOXA2 and FOXA3 transcription factor networks, organism-specific biosystem; HIF-1-alpha transcription factor network, organism-specific biosystem; Myometrial Relaxation and Contraction Pathways, organism-specific biosystem; PERK regulated gene expression, organism-specific biosystem;
Function: insulin-like growth factor binding;

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