Recombinant Human HSPA5 Protein, His-tagged

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Recombinant Human HSPA5 Protein, His-tagged

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Cat.No. : HSPA5-014H
Product Overview : Recombinant full length human HSPA5 protein (2-654) with a N-terminal Histidine tag was expressed in E. coli.
Description : The protein encoded by this gene is a member of the heat shock protein 70 (HSP70) family. It is localized in the lumen of the endoplasmic reticulum (ER), and is involved in the folding and assembly of proteins in the ER. As this protein interacts with many ER proteins, it may play a key role in monitoring protein transport through the cell.
Source : E. coli
Species : Human
Tag : His
Form : 50 mM HEPES, pH 8.0, 150 mM sodium chloride, 1 mM DTT, and 10% glycerol
Bio-activity : ATPase activity confirmed by ADP detection assay
Molecular Mass : 74.6 kDa
Protein length : 2-654
Purity : ≥85% estimated by SDS-PAGE
Stability : ≥ 1 year
Storage : Store at -80 centigrade
Shipping : Dry ice in continental US; may vary elsewhere
SDS-PAGE analysis of HSPA5. :

Lane 1: MW Markers
Lane 2: HSPA5 (4 µg)
Lane 3: HSPA5 (2 µg)
Lane 4: HSPA58 (1 µg)

ATPase Activity of HSPA5 :

Gene Name : HSPA5 heat shock protein family A (Hsp70) member 5 [ Homo sapiens (human) ]
Official Symbol : HSPA5
Synonyms : HSPA5; heat shock protein family A (Hsp70) member 5; BIP; MIF2; GRP78; HEL-S-89n; endoplasmic reticulum chaperone BiP; 78 kDa glucose-regulated protein; HSP70 family protein 5; binding-immunoglobulin protein; endoplasmic reticulum lumenal; Ca(2+)-binding protein grp78; epididymis secretory sperm binding protein Li 89n; glucose-regulated protein, 78kDa; heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa); heat shock protein 70 family protein 5; heat shock protein family A member 5; immunoglobulin heavy chain-binding protein; EC 3.6.4.10
Gene ID : 3309
mRNA Refseq : NM_005347
Protein Refseq : NP_005338
MIM : 138120
UniProt ID : P11021
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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