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Official Full Name heat shock protein 70kDa family, member 13
Background The protein encoded by this gene is a member of the heat shock protein 70 family and is found associated with microsomes. Members of this protein family play a role in the processing of cytosolic and secretory proteins, as well as in the removal of denatured or incorrectly-folded proteins. The encoded protein contains an ATPase domain and has been shown to associate with a ubiquitin-like protein.
Synonyms HSPA13; heat shock protein 70kDa family, member 13; STCH, stress 70 protein chaperone, microsome associated, 60kD , stress 70 protein chaperone, microsome associated, 60kDa; heat shock 70 kDa protein 13; HSP13_HUMAN; MGC133835; Microsomal stress 70 protein ATPase core; Microsomal stress-70 protein ATPase core; Stress 70 protein chaperone microsome associated 60 kDa protein; Stress-70 protein chaperone microsome-associated 60 kDa protein; stress 70 protein chaperone, microsome-associated, 60kD; stress 70 protein chaperone, microsome-associated, 60kDa; STCH
    • Species :
    • Chicken
    • Human
    • Mouse
    • Rat
    • Rhesus Macaque
    • Zebrafish
    • Source :
    • E.coli
    • HEK293
    • HEK293T
    • Mammalian Cell
    • Tag :
    • GST
    • His
    • MYC/DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human HSPA13-13982H Recombinant Human HSPA13, GST-tagged E.coli GST
    Human HSPA13-3408H Recombinant Human HSPA13, His-tagged E.coli His
    Human HSPA13-5133H Recombinant Human HSPA13 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Human HSPA13-5358HCL Recombinant Human HSPA13 293 Cell Lysate HEK293 N/A
    Mouse Hspa13-489M Recombinant Mouse Hspa13 Protein, MYC/DDK-tagged HEK293T MYC/DDK
    Mouse HSPA13-7902M Recombinant Mouse HSPA13 Protein Mammalian Cell His
    Rat HSPA13-2942R Recombinant Rat HSPA13 Protein Mammalian Cell His
    Rhesus Macaque HSPA13-2163R Recombinant Rhesus monkey HSPA13 Protein, His-tagged Mammalian Cell His
    Chicken HSPA13-2492C Recombinant Chicken HSPA13 Mammalian Cell His
    Zebrafish HSPA13-5584Z Recombinant Zebrafish HSPA13 Mammalian Cell His

    hspa13 involved in several pathways and played different roles in them. We selected most pathways hspa13 participated on our site, such as Cellular response to heat stress, Cellular responses to stress, Regulation of HSF1-mediated heat shock response, which may be useful for your reference. Also, other proteins which involved in the same pathway with hspa13 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Cellular response to heat stress HSPA7; HSPA14; NUP50; EEF1A1; PTGES3; ST13; BAG5; DNAJC7; HSPA13; RPS19BP1
    Cellular responses to stress HIST3H2BB; HIST1H1C; WIPI2; DPF1; POT1A; HSPA12B; HSBP1; HIST1H1E; H1F0; TINF2
    Regulation of HSF1-mediated heat shock response HSPH1; HSPA12B; DNAJC2; HSPA14; DNAJB6; DNAJC7; BAG3; RPS19BP1; KIAA1967; ST13

    hspa13 has several biochemical functions, for example, ATP binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by hspa13 itself. We selected most functions hspa13 had, and list some proteins which have the same functions with hspa13. You can find most of the proteins on our site.

    Function Related Protein
    protein binding SPG20; UBR4; PRDX6; MAVS; AAK1; UQCC1; NCK2; DGKQ; CHPF; CD59

    hspa13 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with hspa13 here. Most of them are supplied by our site. Hope this information will be useful for your research of hspa13.

    UBQLN1; SGTA; UBQLN1; SSR1; BAG6; RMI1; POLE4; UBQLN4; cona_canen; env

    Brown, CA; Schmidt, C; et al. In vitro screen of prion disease susceptibility genes using the scrapie cell assay. HUMAN MOLECULAR GENETICS 23:5102-5108(2014).
    Zhu, YF; Ren, CL; et al. Gene expression of Hsp70, Hsp90 and Hsp110 families in normal palate and cleft palate during mouse embryogenesis. TOXICOLOGY AND INDUSTRIAL HEALTH 29:915-930(2013).
    Lloyd, SE; Mead, S; et al. Genetics of prion diseases. CURRENT OPINION IN GENETICS & DEVELOPMENT 23:345-351(2013).
    Grizenkova, J; Akhtar, S; et al. Overexpression of the Hspa13 (Stch) gene reduces prion disease incubation time in mice. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 109:13722-13727(2012).

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