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Official Full Name heat shock 70kDa protein 1-like
Background This gene encodes a 70kDa heat shock protein. In conjunction with other heat shock proteins, this protein stabilizes existing proteins against aggregation and mediates the folding of newly translated proteins in the cytosol and in organelles. The gene is located in the major histocompatibility complex class III region, in a cluster with two closely related genes which also encode isoforms of the 70kDa heat shock protein.
Synonyms HSPA1L; heat shock 70kDa protein 1-like; heat shock 70kD protein like 1; heat shock 70 kDa protein 1-like; HSP70 HOM; hum70t; heat shock 70 kDa protein 1L; heat shock 70kD protein-like 1; heat shock 10kDa protein 1-like; heat shock 70 kDa protein 1-Hom; H
    • Species :
    • Human
    • Rat
    • Source :
    • E.coli
    • HEK293
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human HSPA1L-13985H Recombinant Human HSPA1L, GST-tagged E.coli GST
    Human HSPA1L-1452H Recombinant Human HSPA1L protein, His-tagged E.coli His
    Human HSPA1L-27084TH Recombinant Human HSPA1L Wheat Germ N/A
    Human HSPA1L-5103H Recombinant Human HSPA1L Protein, GST-tagged Wheat Germ GST
    Human HSPA1L-5356HCL Recombinant Human HSPA1L 293 Cell Lysate HEK293 N/A
    Rat Hspa1l-1453R Recombinant Rat Hspa1l protein, His-tagged E.coli His
    Rat HSPA1L-2945R Recombinant Rat HSPA1L Protein Mammalian Cell His

    hspa1l involved in several pathways and played different roles in them. We selected most pathways hspa1l participated on our site, such as Spliceosome, MAPK signaling pathway, Protein processing in endoplasmic reticulum, which may be useful for your reference. Also, other proteins which involved in the same pathway with hspa1l were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Spliceosome SRSF5A; CCDC12; HNRPKL; HSP70; TRA2B; SRSF6B; HSPA1L; SRSF2A; HSPA8; U2AF2
    MAPK signaling pathway HSPA1L; PPP3R1B; MAPK6; FGFR3; PPM1B; GADD45AB; PAK1; CACNA1C; CACNA1SA; TGFB1
    Protein processing in endoplasmic reticulum GSBP9; UBE2D2A; BAXA; EIF2AK3; MBTPS2; ERO1L; SAR1AB; XBP1; HNF4B; EDEM2
    Endocytosis VPS26A; TSG101; FGFR3; DNM2A; RAB11FIP5; FOLR2; RAB5AA; NEDD4L; ADRB3B; STAM
    Antigen processing and presentation HSPA1L; TAPBP; PSME2; H2-Q10; TAP1; HLA-DQB1; RFXAP; HLA-DQA2; KLRD1; CD8A
    Estrogen signaling pathway SHC3; KCNJ6; GNAO1; PIK3R1; HSP90AB1; CALM2; PRKCD; ESR1; MAP2K2; PLCB3
    Legionellosis NAIP6; HSPD1; SAR1A; HSPA6; CASP7; CXCL1; PYCARD; EEF1A1; NAIP7; EEF1A2
    Toxoplasmosis PIK3CD; MAP3K7; MAPK12; PIK3CA; LAMB4; HLA-DQA1; IL12B; CD40LG; HLA-DRB3; HLA-DOA
    Influenza A IFNB1; STAT1; IFIH1; ADAR; LOC100686744; AGFG1; PABPN1; TLR4; FURIN; EIF2AK2
    Epstein-Barr virus infection PIK3CG; PLCG1; CD44; HSPB2; PRKACG; RB1; TP53; XPO1; TRAF2; IKBKG

    hspa1l has several biochemical functions, for example, ATP binding, heat shock protein binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by hspa1l itself. We selected most functions hspa1l had, and list some proteins which have the same functions with hspa1l. You can find most of the proteins on our site.

    Function Related Protein
    ATP binding CDK6; SMC3; EIF4A2; TNK2; ITPKB; GAK; ERBB2; IGF1R; IP6K2; ERBB4A
    heat shock protein binding DMPK; NFKBIA; TFAM; HSPA9; LIMK1; GPR37; NFKB1; DNAJC9; TOMM34; HSPA1A
    protein binding IFNGR1; KIAA1958; C4BPB; MRAP; ITPRIPL1; PPP1R7; KIRREL3; HDHD3; PNMA2; MPPE1
    ubiquitin protein ligase binding FHIT; UBE2G1B; SLC25A5; CUL4A; SMAD5; GSK3B; IKBKG; UBE2A; LTBR; SMAD2
    unfolded protein binding HSPA1L; SSUH2.2; SERPINH1; DNAJB8; TAPBP; HSPE1; NPM1; CCT2; PPIA; H2-KE2

    hspa1l has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with hspa1l here. Most of them are supplied by our site. Hope this information will be useful for your research of hspa1l.


    Nishida, Y; Aida, K; et al. Antibody-Validated Proteins in Inflamed Islets of Fulminant Type 1 Diabetes Profiled by Laser-Capture Microdissection Followed by Mass Spectrometry. PLOS ONE 9:-(2014).
    Zhang, XM; Tanguay, RM; et al. Variants of HSPA1A in Combination with Plasma Hsp70 and Anti-Hsp70 Antibody Levels Associated with Higher Risk of Acute Coronary Syndrome. CARDIOLOGY 119:57-64(2011).

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