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Active Recombinant Mouse FLT4 protein, mFc-tagged

Cat.No. : FLT4-391M
Product Overview : Recombinant Mouse FLT4 protein(Tyr 25 - Asp 770), fused with mFc tag, was expressed in HEK293.
  • Specification
  • Gene Information
  • Related Products
Source : HEK293
Species : Mouse
Tag : mFc
Form : Lyophilized from 0.22 μm filtered solution in 50 mM Tris, 100 mM Glycine, pH7.5, 10% trehalose.
Bio-activity : Immobilized Human VEGF-C, His Tag at 5 μg/mL (100 μL/well) can bind Mouse VEGF R3 Protein, Mouse IgG2a Fc Tag with a linear range of 1-10 ng/mL.
Molecular Mass : This protein carries a mouse IgG2a Fc tag at the C-terminus.The protein has a calculated MW of 111.5 kDa. The protein migrates as 116-125 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Protein Length : Tyr 25 - Asp 770
Endotoxin : Less than 0.1 EU per μg by the LAL method.
Purity : >95% as determined by SDS-PAGE.
Storage : For long term, the product should be stored at lyophilized state at -20°C or lower.Please avoid repeated freeze-thaw cycles. This product is stable after at:
-20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution.
Reconstitution : It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents.
Gene Name : Flt4 FMS-like tyrosine kinase 4 [ Mus musculus ]
Official Symbol : FLT4
Synonyms : FLT4; FMS-like tyrosine kinase 4; vascular endothelial growth factor receptor 3; chylous ascites; receptor protein tyrosine kinase; tyrosine-protein kinase receptor FLT4; vascular endothelial growth factor receptor-3; Chy; Flt-4; VEGFR3; VEGFR-3; AI323512;
Gene ID : 14257
mRNA Refseq : NM_008029
Protein Refseq : NP_032055

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (6)

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Does FLT4 protein correlate with tumor-related markers? 09/14/2022

FLT4 protein is associated with various tumor-related markers such as malignant lymphoma, breast cancer, and lung cancer.

Is there a relationship between FLT4 protein and lymphedema? 04/16/2022

FLT4 protein is a key regulator of lymphedema and plays an important role in lymphangiogenesis and lymphatic drainage.

Is FLT4 protein associated with congenital lymphedema? 06/01/2021

Yes, mutations in the FLT4 protein can lead to congenital lymphedema, a condition caused by abnormal lymphatic vessel development.

What is the potential of FLT4 protein in cancer treatment? 10/16/2020

The protein is considered an important target in anticancer therapy, and inhibition of its activity may reduce tumor angiogenesis and metastasis.

What is the role of FLT4 protein in pulmonary hypertension? 07/16/2020

FLT4 protein plays an important role in pulmonary hypertension, and upregulation of its activity may lead to pathological changes such as vascular remodeling and pulmonary artery stenosis.

What is the role of FLT4 protein in angiogenesis? 04/21/2019

This is involved in the regulation of angiogenesis and lymphangiogenesis by binding to vascular endothelial growth factor C (VEGF-C) and vascular endothelial growth factor D (VEGF-D).

Customer Reviews (3)

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Reviews
09/05/2022

    The catalytic activity of FLT4 is very strong, which can significantly improve the selectivity and yield of chemical reactions, and its application potential is great.

    09/26/2019

      We were reassured that the quality of FLT4 was consistent.

      03/23/2019

        Using FLT4 for experiments, I can focus more on experimental design and data analysis without worrying about the reproducibility of experimental results.

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