flt3l
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  • Official Full Name
  • FMS-like tyrosine kinase 3 ligand
  • Background
  • FLT3L, also known as flt3 ligand, acts as a growth factor that increases the number of immune cells by activating the hematopoietic progenitors. It is a small molecule which also induces the mobilization of the hematopoietic progenitors and stem cells in
  • Synonyms
  • Flt3l; FMS-like tyrosine kinase 3 ligand; Ly72L; Flt3lg; fms-related tyrosine kinase 3 ligand; flt3 ligand
Cat.#:Flt3l-188MTag:N/A
Source (Host):NS0Species:Mouse
Product nameRecombinant Mouse FMS-like Tyrosine Kinase 3 Ligand
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Cat.#:Flt3l-4372MTag:
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Flt3l Protein
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Cat.#:FLT3L-20HTag:His
Source (Host):Barley grain (Hordeum vulgare)Species:Human
Product nameRecombinant Human FLT3L, His-tagged
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Cat.#:Flt3l-03MTag:N/A
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Flt3l
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Cat.#:Flt3l-456MTag:Fc
Source (Host):HEK293Species:Mouse
Product nameRecombinant Mouse Flt3l, Fc-tagged
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Cat.#:Flt3l-457MTag:His
Source (Host):HEK293Species:Mouse
Product nameRecombinant Mouse Flt3l protein, His-tagged
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Cat.#:Flt3l-63MTag:His
Source (Host):Insect cellSpecies:Mouse
Product nameRecombinant Mouse Flt3l protein, His-tagged
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Cat.#:Flt3l-762MTag:His/T7
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Flt3l protein, His & T7-tagged
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Cat.#:Flt3l-8704MTag:Fc
Source (Host):HEK293Species:Mouse
Product nameRecombinant Mouse Flt3l, Fc tagged
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Cat.#:Flt3l-936MTag:
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Flt3l protein
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Cat.#:FLT3-1229MTag:N/A
Source (Host):E. coliSpecies:Macaca mulatta
Product nameRecombinant Macaca mulatta FLT3 Ligand
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Cat.#:FLT3LG-1387MCLTag:
Source (Host):HEK293Species:Mouse
Product nameRecombinant Mouse FLT3LG cell lysate
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Involved Pathway

Flt3l involved in several pathways and played different roles in them. We selected most pathways Flt3l participated on our site, such as Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, Pathways in cancer, which may be useful for your reference. Also, other proteins which involved in the same pathway with Flt3l were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Cytokine-cytokine receptor interaction
TNFRSF4; IL13; Ifna11; TNFRSF12A; ACVR1BA; TNFSF8; FAS; FLT1; TNFRSF19; CCL3
Hematopoietic cell lineage
FCGR1A; ITGAM; CSF3R; CR1; CD3G; THPO; CD9; HLA-DRB1; CSF1R; IL6
Pathways in cancer
DAPK1; NFKB1; PIK3R3; FZD8; FN1; CBLC; PML; PIK3CG; KITLG; BCL2

Protein Function

Flt3l has several biochemical functions, for example, cytokine activity, protein homodimerization activity, receptor tyrosine kinase binding. Some of the functions are cooperated with other proteins, some of the functions could acted by Flt3l itself. We selected most functions Flt3l had, and list some proteins which have the same functions with Flt3l. You can find most of the proteins on our site.
Function
Related Protein
Function cytokine activity
Related Protein Gm13290; IFNE; VEGFA; IFNA16; GREM1; CMTM1; MIF; IFNA8; ILTIFB; GM13287
Function protein homodimerization activity
Related Protein PVRL2L; CADM1B; TERF1; CPNE1; TFAP2B; SETMAR; SUPV3L1; CAV2; HSP90AA1; TIRAP
Function receptor tyrosine kinase binding
Related Protein PIK3R2; NRG1; MYOC; PITPNM3; SOCS5; SHC3; LRP4; PCNA; FNTA; ZNF259

Flt3l Related Articles

Ramos, MIP; Karpus, ON; et al. Absence of Fms-like tyrosine kinase 3 ligand (Flt3L) signalling protects against collagen-induced arthritis. ANNALS OF THE RHEUMATIC DISEASES 74:211-219(2015).
Hodge, DL; Berthet, C; et al. IFN-gamma AU-rich element removal promotes chronic IFN-gamma expression and autoimmunity in mice. JOURNAL OF AUTOIMMUNITY 53:33-45(2014).