flt1

Home / Products / flt1

flt1

Official Full Name fms-related tyrosine kinase 1
Background This gene encodes a member of the vascular endothelial growth factor receptor (VEGFR) family. VEGFR family members are receptor tyrosine kinases (RTKs) which contain an extracellular ligand-binding region with seven immunoglobulin (Ig)-like domains, a transmembrane segment, and a tyrosine kinase (TK) domain within the cytoplasmic domain. This protein binds to VEGFR-A, VEGFR-B and placental growth factor and plays an important role in angiogenesis and vasculogenesis. Expression of this receptor is found in vascular endothelial cells, placental trophoblast cells and peripheral blood monocytes. Multiple transcript variants encoding different isoforms have been found for this gene. Isoforms include a full-length transmembrane receptor isoform and shortened, soluble isoforms. The soluble isoforms are associated with the onset of pre-eclampsia.[provided by RefSeq, May 2009]
Synonyms FLT1; fms-related tyrosine kinase 1; FLT; FLT-1; VEGFR1; VEGFR-1; vascular endothelial growth factor receptor 1; fms-like tyrosine kinase 1; tyrosine-protein kinase FRT; tyrosine-protein kinase receptor FLT; vascular permeability factor receptor; fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor);
    • Species :
    • Chicken
    • Human
    • Mouse
    • Pig
    • Rat
    • Rhesus macaque
    • Zebrafish
    • Source :
    • CHO
    • E.coli
    • HEK293
    • HEK293F
    • HEK293T
    • Human
    • Human Cell
    • Insect Cell
    • Mammalian Cell
    • NS0
    • Sf21 Insect Cell
    • Sf9 Insect Cell
    • Wheat Germ
    • Tag :
    • DDK
    • Fc
    • Fc Chimera
    • GST
    • His
    • Avi
    • T7
    • His-Avi
    • mFc
    • Mouse
    • IgG2a
    • Myc/DDK
    • Myc
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human FLT1 & KDR-P1006H Recombinant Human FLT1/KDR, Fc-tagged therapeutic protein CHO Fc
    Human FLT1-1015H Recombinant Human Fms-Related Tyrosine Kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor), GST-tagged Sf9 Insect Cell GST
    Human FLT1-1221H Recombinant Human Fms-Related Tyrosine Kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) Insect Cell N/A
    Human FLT1-1222H Recombinant Human Fms-Related Tyrosine Kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor), His-tagged Sf9 Insect Cell His
    Human FLT1-12H Recombinant Human FLT1 protein Insect Cell N/A
    Human FLT1-1407H Recombinant Human FLT1 (Active), GST-tagged Sf9 Insect Cell GST
    Human FLT1-1909HCL Recombinant Human FLT1 cell lysate Human Cell N/A
    Human FLT1-190H Recombinant Human FLT1 Protein, Fc-tagged HEK293 Fc
    Human FLT1-2341H Recombinant Human FLT1 Protein, MYC/DDK-tagged HEK293 Myc/DDK
    Human FLT1-241H Recombinant Human FLT1, Fc Chimera Sf21 Insect Cell Fc Chimera
    Human FLT1-310HB Recombinant Human FLT1 protein, His-Avi-tagged, Biotinylated HEK293 His-Avi
    Human FLT1-31708TH Recombinant Human FLT1, His-tagged His
    Human FLT1-31709TH Recombinant Human FLT1 N/A
    Human FLT1-31710TH Recombinant Human FLT1, His-tagged His
    Human FLT1-31711TH Recombinant Human FLT1 N/A
    Human FLT1-31713TH Recombinant Human FLT1, His-tagged His
    Human FLT1-31714TH Recombinant Human FLT1, His-tagged E.coli His
    Human FLT1-318H Recombinant Human FLT1, GST-tagged, Active Sf9 Insect Cell GST
    Human FLT1-321H Recombinant Human FLT1 protein, His-Avi-tagged HEK293 His-Avi
    Human FLT1-32H Recombinant Human FLT1, His-tagged Human Cell His
    Human FLT1-3809H Recombinant Human FLT1, His tagged Human Cell His
    Human FLT1-3810H Recombinant Human FLT1 Protein, His-Avi-tagged, Biotinylated HEK293 His/Avi
    Human FLT1-4366H Recombinant Human FLT1 Protein E.coli N/A
    Human FLT1-4367H Recombinant Human FLT1 Protein, GST-tagged Insect Cell GST
    Human FLT1-4369H Recombinant Human FLT1 Protein, GST-tagged Wheat Germ GST
    Human FLT1-530H Recombinant Human FLT1 protein, His-tagged HEK293F His
    Human FLT1-544H Recombinant Human FLT1, His-tagged Sf9 Insect Cell His
    Human FLT1-5899H Recombinant Human FLT1 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Human FLT1-615H Recombinant Human FLT1, Fc-tagged, Biotinylated Human Cell Fc
    Human FLT1-616H Recombinant Human FLT1, Fc-tagged Human Cell Fc
    Human FLT1-7650H Recombinant Human FLT1 N/A
    Human FLT1-78H Recombinant Human Fms-related Tyrosine Kinase 1, 3 Domains Insect Cell N/A
    Human FLT1-79H Recombinant Human Fms-related Tyrosine Kinase 1, 4 Domains Insect Cell N/A
    Human FLT1-80H Recombinant Human Fms-related Tyrosine Kinase 1, 5 Domains Insect Cell N/A
    Human FLT1-81H Recombinant Human Fms-related Tyrosine Kinase 1, 5 Domains, Fc-tagged Insect Cell Fc
    Human FLT1-82H Recombinant Human Fms-related Tyrosine Kinase 1, 6 Domains Insect Cell N/A
    Human FLT1-899H Recombinant Human Fms-Related Tyrosine Kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor), His-tagged Human His
    Human FLT1-938H Recombinant Human FLT1 Protein, DDK-tagged Sf9 Insect Cell DDK
    Human FLT1-979H Recombinant Human Fms-related Tyrosine Kinase 1, Fc Chimera Insect Cell Fc
    Human VEGFR1&VEGFR2-P019H Recombinant Human FLT1/VEGFR2, Fc-tagged therapeutic protein CHO Fc
    Human VEGFR1&VEGFR2-P09H Recombinant Human FLT1/VEGFR2, Fc-tagged therapeutic protein Fc
    Mouse Flt1-12M Recombinant Mouse Flt1 protein, His-tagged HEK293 His
    Mouse Flt1-1785M Recombinant Mouse Flt1 Protein, Fc-tagged NS0 Fc
    Mouse Flt1-1786M Recombinant Mouse Flt1 Protein, Fc-tagged NS0 Fc
    Mouse Flt1-1838M Recombinant Mouse Flt1 protein, His-tagged E.coli His
    Mouse Flt1-3044M Recombinant Mouse Flt1 Protein, Myc/DDK-tagged HEK293T Myc/DDK
    Mouse FLT1-5927M Recombinant Mouse FLT1 Protein Mammalian Cell His
    Mouse Flt1-7210M Recombinant Mouse Flt1 Protein, Fc-tagged Insect Cell Fc
    Mouse Flt1-8114M Recombinant Mouse Flt1 protein, mFc-tagged HEK293 mFc
    Rat FLT1-1207RCL Recombinant Rat FLT1 cell lysate Human Cell N/A
    Rat Flt1-1840R Recombinant Rat Flt1 protein, His-tagged E.coli His
    Rat Flt1-1841R Recombinant Rat Flt1 protein, His & T7-tagged E.coli His/T7
    Rat FLT1-2364R Recombinant Rat FLT1 Protein Mammalian Cell His
    Rat Flt1-8712R Recombinant Rat Flt1, His tagged Human Cell His
    Rhesus macaque FLT1-379R Recombinant Rhesus macaque FLT1 protein, Mouse IgG2a Fc-tagged, low endotoxin HEK293 Mouse/IgG2a/Fc
    Chicken FLT1-5825C Recombinant Chicken FLT1 Mammalian Cell His
    Zebrafish FLT1-2299Z Recombinant Zebrafish FLT1 Mammalian Cell His
    Pig FLT1-1839P Recombinant Pig FLT1 protein, His & GST-tagged E.coli His/GST

    flt1 involved in several pathways and played different roles in them. We selected most pathways flt1 participated on our site, such as Ras signaling pathway, Rap signaling pathway, Cytokine-cytokine receptor interaction, which may be useful for your reference. Also, other proteins which involved in the same pathway with flt1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Ras signaling pathway RASAL3; NF1; PIK3CB; KSR2; GNG13; SHOC2; PDGFC; PLA2G4D; KSR1; GAB1
    Rap signaling pathway KRIT1; VEGFA; FGF16; Kitl; MAPK12; MAPK11; LPAR2; MAPK3; Fgf15; VAV2
    Cytokine-cytokine receptor interaction IFNK; IFNAR2; IL7; IL5RA; ACVR1BA; CCR8; TGFBR2; CSF3R; CNTF; IL2RGB
    HIF- signaling pathway MAP2K2; MTOR; FLT1; HK1; Trf; INS2; NFKB1; CAMK2D; ANGPT2; EPO
    Endocytosis IGF1RA; RAB5AB; RAB11FIP1; RAB22A; GRK7B; ARFGEF1; FGFR2; CYTH3; GIT1; SNX2
    PIK-Akt signaling pathway PPP2CA; IFNA13; COL6A5; GNG5; Kitl; FGF4; PPP2R1B; LPAR6; COL6A6; PDPK1
    Focal adhesion TNR; TNC; PTENB; TNK1; RAP1B; PIK3CB; LAMB4; BCL2A; RAC1B; CAV1
    Transcriptional misregulation in cancer ATM; ELK4; BIRC3; EWSR1; HIST3H3; H3F3C; GOLPH3L; TGFBR2; FCGR1A; PML
    Rheumatoid arthritis HLA-DPA1; MMP3; HLA-DRB4; ATP6V1E2; ATP6V1A; ATP6V0E1; CXCL12; Il23a; ATP6V0E2; MMP1

    flt1 has several biochemical functions, for example, ATP binding, VEGF-A-activated receptor activity, VEGF-B-activated receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by flt1 itself. We selected most functions flt1 had, and list some proteins which have the same functions with flt1. You can find most of the proteins on our site.

    Function Related Protein
    ATP binding DHX36; MAP3K10; MYO3B; SGK2A; ERBB3A; MAP2K1; PSMC5; TGFBR1B; GRK7; KIF5C
    VEGF-A-activated receptor activity FLT1
    VEGF-B-activated receptor activity FLT1
    growth factor binding ACVR2B; IGFBP2B; IL6ST; KDR; SDCBP; A2M; ACVR2A; FLT1; RHBDF2; ERBB3
    placental growth factor-activated receptor activity FLT1
    protein binding CT45A3; TRIM41; DYRK1A; UNC119B; SIRT3; TRIM26; CEP152; CDC25A; HNRNPR; TAF8
    transmembrane receptor protein tyrosine kinase activity RET; INSRB; EPHA4B; KITA; MERTK; RYK; IGF1RA; KIT; NTRK3; KITB
    vascular endothelial growth factor-activated receptor activity FLT4; NRP1A; NRP2B; NRP2; PDGFRA; NRP1B; FLT1; FLT3; KDR; NRP1

    flt1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with flt1 here. Most of them are supplied by our site. Hope this information will be useful for your research of flt1.

    VEGFA; PTPRJ; PGF; PIK3R1; VEGFA; CRKL

    Ahmadova, Z; Yagublu, V; et al. Fluorescent Resonance Energy Transfer Imaging of VEGFR Dimerization. ANTICANCER RESEARCH 34:2123-2133(2014).
    Suspitsin, EN; Kashyap, A; et al. Evidence for angiogenesis-independent contribution of VEGFR1 (FLT1) in gastric cancer recurrence. MEDICAL ONCOLOGY 30:-(2013).

    Related Services & Products

    Apply For A Coupon

    $50 OFF Your First Purchase

    Apply For a Coupon

    Enter your email here to subscribe.

    creative biomart inc.

    Easy access to products and services you need from our library via powerful searching tools.

    Follow Us

    Copyright © 2021 Creative BioMart. All Rights Reserved. Terms and Conditions | Privacy Policy