Recombinant Human FLT4 Protein, GST-tagged
Cat.No. : | FLT4-4379H |
Product Overview : | Human FLT4 partial ORF ( NP_002011, 34 a.a. - 133 a.a.) recombinant protein with GST-tag at N-terminal. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a tyrosine kinase receptor for vascular endothelial growth factors C and D. The protein is thought to be involved in lymphangiogenesis and maintenance of the lymphatic endothelium. Mutations in this gene cause hereditary lymphedema type IA. [provided by RefSeq |
Source : | Wheat Germ |
Species : | Human |
Tag : | GST |
Molecular Mass : | 36.63 kDa |
AA Sequence : | ITEESHVIDTGDSLSISCRGQHPLE WAWPGAQEAPATGDKDSEDTGVVRD CEGTDARPYCKVLLLHEVHANDTGS YVCYYKYIKARIEGTTAASSYVFVR |
Applications : | Enzyme-linked Immunoabsorbent Assay Western Blot (Recombinant protein) Antibody Production Protein Array |
Notes : | Best use within three months from the date of receipt of this protein. |
Storage : | Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
Storage Buffer : | 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
Gene Name : | FLT4 fms-related tyrosine kinase 4 [ Homo sapiens ] |
Official Symbol : | FLT4 |
Synonyms : | FLT4; fms-related tyrosine kinase 4; vascular endothelial growth factor receptor 3; PCL; VEGFR3; FLT-4; VEGFR-3; soluble VEGFR3 variant 1; soluble VEGFR3 variant 2; soluble VEGFR3 variant 3; fms-like tyrosine kinase 4; tyrosine-protein kinase receptor FLT4; FLT41; LMPH1A; |
Gene ID : | 2324 |
mRNA Refseq : | NM_002020 |
Protein Refseq : | NP_002011 |
MIM : | 136352 |
UniProt ID : | P35916 |
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Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
- Q&As
- Reviews
Q&As (6)
Ask a questionFLT4 protein is associated with various tumor-related markers such as malignant lymphoma, breast cancer, and lung cancer.
FLT4 protein is a key regulator of lymphedema and plays an important role in lymphangiogenesis and lymphatic drainage.
Yes, mutations in the FLT4 protein can lead to congenital lymphedema, a condition caused by abnormal lymphatic vessel development.
The protein is considered an important target in anticancer therapy, and inhibition of its activity may reduce tumor angiogenesis and metastasis.
FLT4 protein plays an important role in pulmonary hypertension, and upregulation of its activity may lead to pathological changes such as vascular remodeling and pulmonary artery stenosis.
This is involved in the regulation of angiogenesis and lymphangiogenesis by binding to vascular endothelial growth factor C (VEGF-C) and vascular endothelial growth factor D (VEGF-D).
Customer Reviews (3)
Write a reviewThe catalytic activity of FLT4 is very strong, which can significantly improve the selectivity and yield of chemical reactions, and its application potential is great.
We were reassured that the quality of FLT4 was consistent.
Using FLT4 for experiments, I can focus more on experimental design and data analysis without worrying about the reproducibility of experimental results.
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