Active Recombinant Human PTPN9(283-end) Protein, N-GST-tagged
Cat.No. : | PTPN9-208H |
Product Overview : | N-terminal GSTtagged, recombinant human PTP MEG2, amino acid residues 283–end, expressed in E.coli cells. Purified using glutathioneagarose. |
- Specification
- Gene Information
- Related Products
Description : | PTPMEG-2 is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an N-terminal domain that shares a significant similarity with yeast SEC14, which is a protein that has phosphatidylinositol transfer activity and is required for protein secretion through the Golgi complex in yeast. This PTP was found to be activated by polyphosphoinositide, and is thought to be involved in signaling events regulating phagocytosis. |
Source : | E. coli |
Species : | Human |
Tag : | GST |
Protein length : | 283-end |
Form : | 0.466mg/ml of enzyme in 50mM Tris/HCl ph7.5, 150mM NaCl, 10% glycerol, 0.1mM EGTA, 0.03% Brij-35, 0.2mM PMSF, 1mM benzamidine, 0.1% 2-mercaptoethanol. Frozen solution. |
Bio-activity : | 50923U/mg where one unit of PTP MEG2 activity is defined as the release of 1nmole of phosphate/min from the phosphorylated substrate DiFMUP. |
Molecular Mass : | 62.5 kDa |
AA Sequence : | 1 MSPILGYWKI KGLVQPTRLL LEYLEEKYEE HLYERDEGDK WRNKKFELGL EFPNLPYYID 61 GDVKLTQSMA IIRYIADKHN MLGGCPKERA EISMLEGAVL DIRYGVSRIA YSKDFETLKV 121 DFLSKLPEML KMFEDRLCHK TYLNGDHVTH PDFMLYDALD VVLYMDPMCL DAFPKLVCFK 181 KRIEAIPQID KYLKSSKYIA WPLQGWQATF GGGDHPPKSD LVPRGSPEFP HAMTIQELVD 241 YVNARQKQGI YEEYEDIRRE NPVGTFHCSM SPGNLEKNRY GDVPCLDQTR VKLTKRSGHT 301 QTDYINASFM DGYKQKNAYI GTQGPLENTY RDFWLMVWEQ KVLVIVMTTR FEEGGRRKCG 361 QYWPLEKDSR IRFGFLTVTN LGVENMNHYK KTTLEIHNTE ERQKRQVTHF QFLSWPDYGV 421 PSSAASLIDF LRVVRNQQSL AVSNMGARSK GQCPEPPIVV HCSAGIGRTG TFCSLDICLA 481 QLEELGTLNV FQTVSRMRTQ RAFSIQTPEQ YYFCYKAILE FAEKEGMVSS GQNLLAVESQ |
Purity : | Purity 81.2% by SDS-PAGE and Coomassie blue staining. |
Applications : | Drug Discovery & Development |
Storage : | 1 year at -70 centigrade. |
Handling Advice : | Rapidly thaw the vial under cold water and immediately place on ice. Aliquot unused material into prechilled micro-centrifuge tubes and immediately snap-freeze the vials in liquid nitrogen prior to re-storage at -70 centigrade. |
Use/Stability : | On receipt of material store at -70 centigrade. Unopened reagent is stable for a minimum of 1 year from date of shipment when stored at recommended storage temperature. Avoid repeat freeze/thaw cycles. For maximum recovery of product, centrifuge original vial prior to removing the cap. |
Gene Name : | PTPN9 protein tyrosine phosphatase non-receptor type 9 [ Homo sapiens (human) ] |
Official Symbol : | PTPN9 |
Synonyms : | PTPN9; protein tyrosine phosphatase non-receptor type 9; MEG2; PTPMEG2 |
Gene ID : | 5780 |
mRNA Refseq : | NM_002833.4 |
Protein Refseq : | NP_002824.1 |
MIM : | 600768 |
UniProt ID : | P43378 |
Products Types
◆ Recombinant Protein | ||
PTPN9-4496R | Recombinant Rat PTPN9 Protein, His (Fc)-Avi-tagged | +Inquiry |
PTPN9-1300H | Recombinant Human PTPN9 protein(Ala285-Gln593), His&GST-tagged | +Inquiry |
PTPN9-7283M | Recombinant Mouse PTPN9 Protein, His (Fc)-Avi-tagged | +Inquiry |
PTPN9-320H | Recombinant Human PTPN9 Protein, GST-tagged | +Inquiry |
PTPN9-8095H | Recombinant Human PTPN9 protein, His & T7-tagged | +Inquiry |
◆ Lysates | ||
PTPN9-518HCL | Recombinant Human PTPN9 lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
0
Inquiry Basket