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PTPN20B

Official Full Name

protein tyrosine phosphatase, non-receptor type 20B
Overview

The product of this gene belongs to the family of classical tyrosine-specific protein tyrosine phosphatases. Many protein tyrosine phosphatases have been shown to regulate fundamental cellular processes and several are mutated in human diseases. Chromosome 10q contains a segmental duplication resulting in multiple copies of the protein tyrosine phosphatase, non-receptor type 20 gene. The two nearly identical copies are designated as PTPN20A and PTPN20B. A third copy is only partially duplicated and contains a pseudogene, designated as PTPN20C. This gene encodes the more telomeric copy, PTPN20B. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.
Synonyms

PTPN20B; protein tyrosine phosphatase, non-receptor type 20B; protein tyrosine phosphatase, non-receptor type 20; bA42B19.1; DKFZP566K0524; PTP Typ;

Species	Cat.#	Product name	Source (Host)	Tag	Price
Human	PTPN20B-517HCL	Recombinant Human PTPN20A lysate	HEK293	N/A	Inquiry
Rat	PTPN20B-4832R	Recombinant Rat PTPN20B Protein	Mammalian Cell	His	Inquiry
Rat	PTPN20B-4491R	Recombinant Rat PTPN20B Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi	Inquiry
Rat	PTPN20B-4491R-B	Recombinant Rat PTPN20B Protein Pre-coupled Magnetic Beads	HEK293		Inquiry

Involved Pathway
Protein Function
Interacting Protein

PTPN20B involved in several pathways and played different roles in them. We selected most pathways PTPN20B participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with PTPN20B were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein

PTPN20B has several biochemical functions, for example, protein tyrosine phosphatase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by PTPN20B itself. We selected most functions PTPN20B had, and list some proteins which have the same functions with PTPN20B. You can find most of the proteins on our site.

Function	Related Protein
protein tyrosine phosphatase activity	CDC25B;MTMR3;CDC14AB;MTMR2;CDC14AA;PTPRG;DUSP13;PTPRO;DUSP28

PTPN20B has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PTPN20B here. Most of them are supplied by our site. Hope this information will be useful for your research of PTPN20B.