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PTPN18

Official Full Name

protein tyrosine phosphatase, non-receptor type 18 (brain-derived)
Synonyms

PTPN18;protein tyrosine phosphatase, non-receptor type 18 (brain-derived);9649;ENSG00000072135;BDP1;PTP-HSCF;2q21.1;tyrosine-protein phosphatase non-receptor type 18;tyrosine-protein phosphatase non-receptor type 18;brain-derived phosphatase;EC 3.1.3.48;

Type

Cell & Tissue Lysates
Recombinant Proteins
Protein Pre-coupled Magnetic Beads

Species

Human
Mouse
Zebrafish

Source

E.coli
HEK293
HEK293T
Mammalian Cell

Tag

His
His (Fc)
Avi
Myc
DDK
Myc|DDK
N/A
N
GST

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	PTPN18-1437HCL	Recombinant Human PTPN18 cell lysate		N/A		Inquiry
Human	PTPN18-3132H	Recombinant Human PTPN18 Protein, MYC/DDK-tagged	HEK293	Myc/DDK		Inquiry
Human	PTPN18-6229H	Recombinant Human PTPN18 Protein, Myc/DDK-tagged, C13 and N15-labeled	HEK293T	Myc/DDK		Inquiry
Human	PTPN18-2003H	Recombinant Human PTPN18 Protein, His&GST-tagged	E.coli	N-His&GST	Ala311-Val460	Inquiry
Mouse	PTPN18-13679M	Recombinant Mouse PTPN18 Protein	Mammalian Cell	His		Inquiry
Mouse	Ptpn18-5237M	Recombinant Mouse Ptpn18 Protein, Myc/DDK-tagged	HEK293T	Myc/DDK		Inquiry
Mouse	PTPN18-7277M	Recombinant Mouse PTPN18 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Mouse	PTPN18-7277M-B	Recombinant Mouse PTPN18 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Zebrafish	PTPN18-2142Z	Recombinant Zebrafish PTPN18	Mammalian Cell	His		Inquiry

Involved Pathway
Protein Function
Interacting Protein
PTPN18 Related Articles

PTPN18 involved in several pathways and played different roles in them. We selected most pathways PTPN18 participated on our site, such as B Cell Receptor Signaling Pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with PTPN18 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
B Cell Receptor Signaling Pathway	NRAS;FCGR2B;NFKBIA;INPP5D;CDK4;STAP1;NEDD9;DUSP6;NFATC2

PTPN18 has several biochemical functions, for example, non-membrane spanning protein tyrosine phosphatase activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PTPN18 itself. We selected most functions PTPN18 had, and list some proteins which have the same functions with PTPN18. You can find most of the proteins on our site.

Function	Related Protein
non-membrane spanning protein tyrosine phosphatase activity	PTPN18;PTPN9;ACP1;PTPN11;PTPN12;PTPN4;DUSP1
protein binding	KIF2A;RPL23;KDM1A;OGN;AHCYL1;COMMD10;NAE1;MICA;TOP3B

PTPN18 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PTPN18 here. Most of them are supplied by our site. Hope this information will be useful for your research of PTPN18.

PSTPIP1; EGFR; bosutinib; imatinib; SH2D1B; ABL2; GRB2

Akcakaya, P; Caramuta, S; et al. microRNA expression signatures of gastrointestinal stromal tumours: associations with imatinib resistance and patient outcome. BRITISH JOURNAL OF CANCER 111:2091-2102(2014).

Doody, KM; Bottini, N; et al. "PEST control": regulation of molecular barcodes by tyrosine phosphatases. CELL RESEARCH 24:1027-1028(2014).