| Cat. No. : |
RPL8-5549H |
| Description : |
RPL8 (60S ribosomal protein L8) belongs to the ribosomal protein L2Pfamily. Ribosomes, theorganelles that catalyze protein synthesis, consist of a small 40S subunitand a large 60S subunit. The protein belongs to the L2P family of ribosomalproteins. It is located in the cytoplasm and exists as a component of the 60S subunit where it isthought to play a role in aminoacyl-tRNA binding, specifically at theribosomal subunit interface. |
| Source : |
E. coli |
| Species : |
Human |
| Form : |
Liquid.In 20mM Tris-HCl buffer (pH 8.0) containing 2mM DTT, 50% glycerol, 300mM NaCl,2mM EDTA. |
| Molecular Weight : |
30.2kDa (277aa),confirmed by MALDI-TOF. |
| Purity : |
> 90%by SDS - PAGE. |
| Concentration : |
0.25mg/ml (determinedby Bradford assay). |
| Sequences of aminoacids : |
MGSSHHHHHHSSGLVPRGSH MGRVIRGQRK GAGSVFRAHV KHRKGAARLR AVDFAERHGY IKGIVKDIIH DPGRGAPLAKVVFRDPYRFK KRTELFIAAE GIHTGQFVYC GKKAQLNIGN VLPVGTMPEG TIVCCLEEKP GDRGKLARASGNYATVISHN PETKKTRVKL PSGSKKVISS ANRAVVGVVA GGGRIDKPIL KAGRAYHKYK AKRNCWPRVRGVAMNPVEHP FGGGNHQHIG KPSTIRRDAP AGRKVGLIAA RRTGRLRGTK TVQEKEN |
| Storage : |
Can bestored at +4°C short term (1-2 weeks). For long term storage, aliquot andstore at -20°C or -70°C. Avoid repeated freezing and thawing cycles. |
| OfficialSymbol : |
RPL8 |
| Pathways : |
Cap-dependentTranslation Initiation; Cytoplasmic Ribosomal Proteins; DevelopmentalBiology; Diabetes pathways; Eukaryotic Translation Elongation; EukaryoticTranslation Initiation; Eukaryotic Translation Termination; Formation of apool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomalsubunit; Metabolism; Metabolism of mRNA; Nonsense Mediated Decay Independentof the Exon Junction Complex; Ribosome; TNF-alpha/NF-kB Signaling Pathway;Viral mRNA Translation |
