RPL18
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Official Full Name
ribosomal protein L18
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Background
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L18E family of ribosomal proteins. It is located in the cytoplasm. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. -
Synonyms
RPL18; ribosomal protein L18; 60S ribosomal protein L18; L18; RPL 18; OTTHUMP00000242005; OTTHUMP00000242050; OTTHUMP00000242051; OTTHUMP00000242052; OTTHUMP00000242053; OTTHUMP00000242055; OTTHUMP00000242056;
- Involved Pathway
- Protein Function
- Interacting Protein
RPL18 involved in several pathways and played different roles in them. We selected most pathways RPL18 participated on our site, such as Ribosome, which may be useful for your reference. Also, other proteins which involved in the same pathway with RPL18 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Ribosome | RPS9;RPL18;RPL6;MRPL28;RPS28;RSL24D1;RPS14;MRPL17;RPS4X |
RPL18 has several biochemical functions, for example, RNA binding, structural constituent of ribosome. Some of the functions are cooperated with other proteins, some of the functions could acted by RPL18 itself. We selected most functions RPL18 had, and list some proteins which have the same functions with RPL18. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| RNA binding | HNRNPK;RCAN3;ADARB1A;CPSF1;RBMX;RNASEL4;CELF5;SMN2;EIF1AXB |
| structural constituent of ribosome | MRPL22;MRPL37;RPS26L;MRPL27;MRPS18A;MRPS18C;RPS4Y2;RPS2;MRPL47 |
RPL18 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with RPL18 here. Most of them are supplied by our site. Hope this information will be useful for your research of RPL18.
VCAM1; ESR1; ACTB; NFKB2; RELA; MAP3K1; MAP3K14; CDKN1A; Brwd3; midostaurin; 8-aha-camp; ere_dna
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