RPL10A Protein


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Official Full Name ribosomal protein L10a
Background Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L1P family of ribosomal proteins. It is located in the cytoplasm. The expression of this gene is downregulated in the thymus by cyclosporin-A (CsA), an immunosuppressive drug. Studies in mice have shown that the expression of the ribosomal protein L10a gene is downregulated in neural precursor cells during development. This gene previously was referred to as NEDD6 (neural precursor cell expressed, developmentally downregulated 6), but it has been renamed RPL10A (ribosomal protein 10a). As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.
Synonyms RPL10A; ribosomal protein L10a; NEDD6; 60S ribosomal protein L10a; Csa 19; L10A; NEDD-6; neural precursor cell expressed developmentally down-regulated protein 6; Csa-19
    • Species :
    • Cynomolgus Monkey
    • Human
    • Rat
    • Rhesus Macaque
    • Zebrafish
    • Source :
    • E.coli
    • HEK293
    • Mammalian Cell
    • Tag :
    • GST
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human RPL10A-2374H Recombinant Human RPL10A, GST-tagged E.coli GST Inquiry
    Human RPL10A-263H Recombinant Human RPL10A Protein, His-tagged E.coli His Inquiry
    Rat RPL10A-5108R Recombinant Rat RPL10A Protein Mammalian Cell His Inquiry
    Cynomolgus Monkey RPL10A-868C Recombinant Cynomolgus RPL10A Protein, His-tagged Mammalian Cell His Inquiry
    Rhesus Macaque RPL10A-3970R Recombinant Rhesus monkey RPL10A Protein, His-tagged Mammalian Cell His Inquiry
    Zebrafish RPL10A-10037Z Recombinant Zebrafish RPL10A Mammalian Cell His Inquiry
    Human RPL10A-2229HCL Recombinant Human RPL10A 293 Cell Lysate HEK293 N/A Inquiry
    Human RPL10A-3437H Recombinant Human RPL10A protein, His-tagged E.coli His Inquiry
    Human RPL10A-5220H Recombinant Human RPL10A protein, GST-tagged E.coli GST Inquiry

    RPL10A involved in several pathways and played different roles in them. We selected most pathways RPL10A participated on our site, such as Ribosome, which may be useful for your reference. Also, other proteins which involved in the same pathway with RPL10A were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Ribosome RPL3; MRPL27; RPS9; RSL24D1; MRPL21; RPL31; RPL5B; RPL23; RPL24; RPS17

    RPL10A has several biochemical functions, for example, poly(A) RNA binding, protein binding, structural constituent of ribosome. Some of the functions are cooperated with other proteins, some of the functions could acted by RPL10A itself. We selected most functions RPL10A had, and list some proteins which have the same functions with RPL10A. You can find most of the proteins on our site.

    Function Related Protein
    poly(A) RNA binding RBM8A; PARN; RPL31; WDR36; GFM1; TOP1; SNW1; SRSF3; RPS15A; MRPL21
    protein binding EWSR1A; AGPAT4; HYPK; EOMESA; SKA3; MPZL1; MCCC1; FCGR2C; ARRB1; TMEM183A
    structural constituent of ribosome DAP3; RPL10L; MRPL15; MRPS35; RPS14; RPSA; RPL7L1; RPS18; MRPS25; MRPL28

    RPL10A has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with RPL10A here. Most of them are supplied by our site. Hope this information will be useful for your research of RPL10A.

    RGS17; VCAM1; LRRK2; YWHAZ; MAP3K1; MAP3K14; SRPR; ACTB; midostaurin; Srp72; NOP56; Smad6; GABARAP

    Grgic, I; Hofmeister, AF; et al. Discovery of new glomerular disease-relevant genes by translational profiling of podocytes in vivo. KIDNEY INTERNATIONAL 86:1116-1129(2014).
    Drane, L; Ainsley, JA; et al. A transgenic mouse line for collecting ribosome-bound mRNA using the tetracycline transactivator system. FRONTIERS IN MOLECULAR NEUROSCIENCE 7:-(2014).

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