RPL17
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Official Full Name
ribosomal protein L17 -
Overview
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L22P family of ribosomal proteins. It is located in the cytoplasm. This gene has been referred to as rpL23 because the encoded protein shares amino acid identity with ribosomal protein L23 from Halobacterium marismortui; however, its official symbol is RPL17. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the neighboring downstream C18orf32 (chromosome 18 open reading frame 32) gene. -
Synonyms
RPL17;ribosomal protein L17;60S ribosomal protein L17;L17;rpL23;60S ribosomal protein L23;FLJ92089;Gene encoding putative NFkB activating protein;MGC117162;PD 1;PD-1;PD1;RL17_HUMAN
Recombinant Proteins
- Zebrafish
- Human
- Rhesus macaque
- Rat
- Chicken
- Mammalian Cells
- E.coli
- Wheat Germ
- HEK293
- In Vitro Cell Free System
- His
- Non
- GST
- Avi
- Fc
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| RPL17-12030Z | Recombinant Zebrafish RPL17 | Mammalian Cells | Zebrafish | His |
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| RPL17-266H | Recombinant Human RPL17 Protein, His-tagged | E.coli | Human | His |
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| RPL17-30438TH | Recombinant Human RPL17 | Wheat Germ | Human | Non | 185 amino acids |
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| RPL17-3974R | Recombinant Rhesus monkey RPL17 Protein, His-tagged | Mammalian Cells | Rhesus macaque | His |
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| RPL17-5111R | Recombinant Rat RPL17 Protein | Mammalian Cells | Rat | His |
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| RPL17-5446C | Recombinant Chicken RPL17 | Mammalian Cells | Chicken | His |
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| RPL17-8033Z | Recombinant Zebrafish RPL17 | Mammalian Cells | Zebrafish | His |
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| RPL17-2221HCL | Recombinant Human RPL17 293 Cell Lysate | HEK293 | Human | Non |
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| RPL17-1217H | Recombinant Human RPL17 protein, GST-tagged | E.coli | Human | GST | 1-184 aa |
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| RPL17-3791R | Recombinant Rhesus Macaque RPL17 Protein, His (Fc)-Avi-tagged | HEK293 | Rhesus macaque | Avi&Fc&His |
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| RPL17-3791R-B | Recombinant Rhesus Macaque RPL17 Protein Pre-coupled Magnetic Beads | HEK293 | Rhesus macaque |
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| RPL17-439HF | Recombinant Full Length Human RPL17 Protein | In Vitro Cell Free System | Human | Full L. 185 amino acids |
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| RPL17-4770R | Recombinant Rat RPL17 Protein, His (Fc)-Avi-tagged | HEK293 | Rat | Avi&Fc&His |
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| RPL17-4770R-B | Recombinant Rat RPL17 Protein Pre-coupled Magnetic Beads | HEK293 | Rat |
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| RPL17-5184H | Recombinant Human RPL17 protein, GST-tagged | E.coli | Human | GST | 2-184aa |
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Involved Pathway
RPL17 involved in several pathways and played different roles in them. We selected most pathways RPL17 participated on our site, such as Ribosome, which may be useful for your reference. Also, other proteins which involved in the same pathway with RPL17 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Ribosome | RPL36,RPSA,MRPL1,MRPS21,RPS4Y1,MRPS17,RPL21,MRPL34,RPL18A,RPL10A |
Protein Function
RPL17 has several biochemical functions, for example, poly(A) RNA binding,structural constituent of ribosome. Some of the functions are cooperated with other proteins, some of the functions could acted by RPL17 itself. We selected most functions RPL17 had, and list some proteins which have the same functions with RPL17. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| structural constituent of ribosome | MRPL52,RPS3A,RPL23,MRPL1,MRPS17,MRPL20,RSL24D1,RPS2,RPS11,MRPL10 |
| poly(A) RNA binding | ZC3H14,REPIN1,FASN,HIST1H4K,HHATL,ZC3HAV1,RPL4,TES,TBL2,WDR36 |
Interacting Protein
RPL17 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with RPL17 here. Most of them are supplied by our site. Hope this information will be useful for your research of RPL17.
VCAM1;ESR1;PPP2R2B;ESR2;LRRK2;Aurkb;Erh;Ctcf;Cdc5l;Mki67;Sgol2;Trim69;Cdca8;Nhp2l1
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References
- Zhang, Y; Wolfle, T; et al. Interaction of Nascent Chains with the Ribosomal Tunnel Proteins Rpl4, Rpl17, and Rpl39 of Saccharomyces cerevisiae. JOURNAL OF BIOLOGICAL CHEMISTRY 288:33697-33707(2013).
