RPL17

Official Full Name

ribosomal protein L17
Overview

Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L22P family of ribosomal proteins. It is located in the cytoplasm. This gene has been referred to as rpL23 because the encoded protein shares amino acid identity with ribosomal protein L23 from Halobacterium marismortui; however, its official symbol is RPL17. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the neighboring downstream C18orf32 (chromosome 18 open reading frame 32) gene.
Synonyms

RPL17; ribosomal protein L17; 60S ribosomal protein L17; L17; rpL23; 60S ribosomal protein L23; FLJ92089; Gene encoding putative NFkB activating protein; MGC117162; PD 1; PD-1; PD1; RL17_HUMAN;

Type

Recombinant Proteins
Cell & Tissue Lysates
Protein Pre-coupled Magnetic Beads

Species

Chicken
Human
Rat
Rhesus Macaque
Zebrafish

Source

E.coli
HEK293
In Vitro Cell Free System
Mammalian Cell
Wheat Germ

Tag

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	RPL17-266H	Recombinant Human RPL17 Protein, His-tagged	E.coli	His		Inquiry
Human	RPL17-30438TH	Recombinant Human RPL17	Wheat Germ	Non	185 amino acids	Inquiry
Human	RPL17-2221HCL	Recombinant Human RPL17 293 Cell Lysate	HEK293	Non		Inquiry
Human	RPL17-5184H	Recombinant Human RPL17 protein, GST-tagged	E.coli	GST	2-184aa	Inquiry
Human	RPL17-1217H	Recombinant Human RPL17 protein, GST-tagged	E.coli	GST	1-184 aa	Inquiry
Human	RPL17-439HF	Recombinant Full Length Human RPL17 Protein	In Vitro Cell Free System		185 amino acids	Inquiry
Rat	RPL17-5111R	Recombinant Rat RPL17 Protein	Mammalian Cell	His		Inquiry
Rat	RPL17-4770R	Recombinant Rat RPL17 Protein, His (Fc)-Avi-tagged	HEK293	His&Fc&Avi		Inquiry
Rat	RPL17-4770R-B	Recombinant Rat RPL17 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Rhesus Macaque	RPL17-3974R	Recombinant Rhesus monkey RPL17 Protein, His-tagged	Mammalian Cell	His		Inquiry
Rhesus Macaque	RPL17-3791R	Recombinant Rhesus Macaque RPL17 Protein, His (Fc)-Avi-tagged	HEK293	His&Fc&Avi		Inquiry
Rhesus Macaque	RPL17-3791R-B	Recombinant Rhesus Macaque RPL17 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Zebrafish	RPL17-8033Z	Recombinant Zebrafish RPL17	Mammalian Cell	His		Inquiry
Zebrafish	RPL17-12030Z	Recombinant Zebrafish RPL17	Mammalian Cell	His		Inquiry
Chicken	RPL17-5446C	Recombinant Chicken RPL17	Mammalian Cell	His		Inquiry

Involved Pathway
Protein Function
Interacting Protein
Other Resource

RPL17 involved in several pathways and played different roles in them. We selected most pathways RPL17 participated on our site, such as Ribosome, which may be useful for your reference. Also, other proteins which involved in the same pathway with RPL17 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Ribosome	RPS3;MRPL17;RPS8;RPL34;MRPS10;RPL26;RPS27.2;RPL27A;RPS28

RPL17 has several biochemical functions, for example, poly(A) RNA binding, structural constituent of ribosome. Some of the functions are cooperated with other proteins, some of the functions could acted by RPL17 itself. We selected most functions RPL17 had, and list some proteins which have the same functions with RPL17. You can find most of the proteins on our site.

Function	Related Protein
poly(A) RNA binding	SORBS2;CCDC55;NSA2;DAP3;DDX5;MRPS30;NOL10;RPL7;SMNDC1
structural constituent of ribosome	RPL31;MRPS9;RPS26;RPL21;RPL18A;RPL35A;RPS4Y1;MRPL36;MRPS6

RPL17 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with RPL17 here. Most of them are supplied by our site. Hope this information will be useful for your research of RPL17.

VCAM1; ESR1; PPP2R2B; ESR2; LRRK2; Aurkb; Erh; Ctcf; Cdc5l; Mki67; Sgol2; Trim69; Cdca8; Nhp2l1

Research Area

Zhang, Y; Wolfle, T; et al. Interaction of Nascent Chains with the Ribosomal Tunnel Proteins Rpl4, Rpl17, and Rpl39 of Saccharomyces cerevisiae. JOURNAL OF BIOLOGICAL CHEMISTRY 288:33697-33707(2013).