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RPL12

Official Full Name

ribosomal protein L12
Background

Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L11P family of ribosomal proteins. It is located in the cytoplasm. The protein binds directly to the 26S rRNA. This gene is co-transcribed with the U65 snoRNA, which is located in its fourth intron. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.
Synonyms

RPL12; ribosomal protein L12; 60S ribosomal protein L12; L12;

Type:
Recombinant Proteins
Cell & Tissue Lysates
Protein Pre-coupled Magnetic Beads

Species :
Chicken
Human
Mouse
Rhesus Macaque
Zebrafish

Source :
E.coli
HEK293
HEK293T
Mammalian Cell
Wheat Germ

Tag :
GST
His
His (Fc)
Avi
Myc
DDK
N/A

Species	Cat.#	Product name	Source (Host)	Tag	Price
Chicken	RPL12-5056C	Recombinant Chicken RPL12	Mammalian Cell	His	Inquiry
Human	RPL12-301606H	Recombinant Human RPL12 protein, GST-tagged	E.coli	GST	Inquiry
Human	RPL12-31150TH	Recombinant Human RPL12	Wheat Germ	N/A	Inquiry
Human	RPL12-883H	Recombinant Human RPL12 Protein, Myc/DDK-tagged, C13 and N15-labeled	HEK293T	Myc/DDK	Inquiry
Human	RPL12-2227HCL	Recombinant Human RPL12 293 Cell Lysate	HEK293	N/A	Inquiry
Human	RPL12-7529H	Recombinant Human RPL12, His-tagged	E.coli	His	Inquiry
Mouse	RPL12-7722M	Recombinant Mouse RPL12 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi	$2,998.00 / 50ug
Mouse	RPL12-14407M	Recombinant Mouse RPL12 Protein	Mammalian Cell	His	Inquiry
Mouse	RPL12-7722M-B	Recombinant Mouse RPL12 Protein Pre-coupled Magnetic Beads	HEK293		Inquiry
Mouse	Rpl12-5584M	Recombinant Mouse Rpl12 Protein, Myc/DDK-tagged	HEK293T	Myc/DDK	Inquiry
Rhesus Macaque	RPL12-3789R-B	Recombinant Rhesus Macaque RPL12 Protein Pre-coupled Magnetic Beads	HEK293		Inquiry
Rhesus Macaque	RPL12-3789R	Recombinant Rhesus Macaque RPL12 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi	$2,998.00 / 50ug
Rhesus Macaque	RPL12-3972R	Recombinant Rhesus monkey RPL12 Protein, His-tagged	Mammalian Cell	His	Inquiry
Zebrafish	RPL12-11566Z	Recombinant Zebrafish RPL12	Mammalian Cell	His	Inquiry

Involved Pathway
Protein Function
Interacting Protein
RPL12 Related Articles

RPL12 involved in several pathways and played different roles in them. We selected most pathways RPL12 participated on our site, such as Ribosome, which may be useful for your reference. Also, other proteins which involved in the same pathway with RPL12 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Ribosome	MRPL32;MRPS15;RPL27;MRPL10;RPS7;RPL34-PS1;RPL18;RPL39;MRPL11

RPL12 has several biochemical functions, for example, poly(A) RNA binding, protein binding, rRNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by RPL12 itself. We selected most functions RPL12 had, and list some proteins which have the same functions with RPL12. You can find most of the proteins on our site.

Function	Related Protein
poly(A) RNA binding	ATXN2;RPS27.2;DDX51;RPS23;CSTF2;AKAP8;KPNB1;MACF1;EIF2S2
protein binding	REEP1;PARP16;CPSF7;CHRNA5;BCL11A;PVRL2;TWF2;MT1H;SNX31
rRNA binding	ERI1;RPS4X;RPS18;RPL9;RNASEL;MRPL20;KDM2B;FASTKD2;RPS4Y1
structural constituent of ribosome	RPL9;RPL22;RPS6;RPS9;RPL26L1;MRPS16;MRPS25;MRPS34;MRPS21

RPL12 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with RPL12 here. Most of them are supplied by our site. Hope this information will be useful for your research of RPL12.

CANX; ZNF16; TUBA4A; CBX1; TTN; UBE2O; midostaurin; NOP56; GABARAP; FN1; ESR1; US11; VIM; VCAM1; RPL10

Delage, L; Giege, P; et al. Four paralogues of RPL12 are differentially associated to ribosome in plant mitochondria. BIOCHIMIE 89:658-668(2007).

SCHMIDT, J; BUBUNENKO, M; et al. A NOVEL OPERON ORGANIZATION INVOLVING THE GENES FOR CHORISMATE SYNTHASE (AROMATIC BIOSYNTHESIS PATHWAY) AND RIBOSOMAL GTPASE CENTER PROTEINS (L11, L1, L10, L12-RPLKAJL) IN CYANOBACTERIUM SYNECHOCYSTIS PCC 6803. JOURNAL OF BIOLOGICAL CHEMISTRY 268:27447-27457(1993).

CRITTEND.LB; OKAZAKI, W; et al. GENETIC INFLUENCE OF RS LOCUS ON SUSCEPTIBILITY TO AVIAN TUMOR VIRUSES .2. ROUS SARCOMA VIRUS ANTIBODY PRODUCTION AFTER STRAIN RPL12 VIRUS INOCULATION. JOURNAL OF THE NATIONAL CANCER INSTITUTE 36:299-&(1966).