RPL12
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Official Full Name
ribosomal protein L12
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Background
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L11P family of ribosomal proteins. It is located in the cytoplasm. The protein binds directly to the 26S rRNA. This gene is co-transcribed with the U65 snoRNA, which is located in its fourth intron. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. -
Synonyms
RPL12; ribosomal protein L12; 60S ribosomal protein L12; L12;
- Involved Pathway
- Protein Function
- Interacting Protein
- RPL12 Related Articles
RPL12 involved in several pathways and played different roles in them. We selected most pathways RPL12 participated on our site, such as Ribosome, which may be useful for your reference. Also, other proteins which involved in the same pathway with RPL12 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
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Ribosome | MRPL32;MRPS15;RPL27;MRPL10;RPS7;RPL34-PS1;RPL18;RPL39;MRPL11 |
RPL12 has several biochemical functions, for example, poly(A) RNA binding, protein binding, rRNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by RPL12 itself. We selected most functions RPL12 had, and list some proteins which have the same functions with RPL12. You can find most of the proteins on our site.
Function | Related Protein |
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poly(A) RNA binding | ATXN2;RPS27.2;DDX51;RPS23;CSTF2;AKAP8;KPNB1;MACF1;EIF2S2 |
protein binding | REEP1;PARP16;CPSF7;CHRNA5;BCL11A;PVRL2;TWF2;MT1H;SNX31 |
rRNA binding | ERI1;RPS4X;RPS18;RPL9;RNASEL;MRPL20;KDM2B;FASTKD2;RPS4Y1 |
structural constituent of ribosome | RPL9;RPL22;RPS6;RPS9;RPL26L1;MRPS16;MRPS25;MRPS34;MRPS21 |
RPL12 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with RPL12 here. Most of them are supplied by our site. Hope this information will be useful for your research of RPL12.
CANX; ZNF16; TUBA4A; CBX1; TTN; UBE2O; midostaurin; NOP56; GABARAP; FN1; ESR1; US11; VIM; VCAM1; RPL10
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