RPL12
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Official Full Name
ribosomal protein L12 -
Overview
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L11P family of ribosomal proteins. It is located in the cytoplasm. The protein binds directly to the 26S rRNA. This gene is co-transcribed with the U65 snoRNA, which is located in its fourth intron. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. -
Synonyms
RPL12;ribosomal protein L12;60S ribosomal protein L12;L12
Recombinant Proteins
- Zebrafish
- Mouse
- Human
- Rhesus macaque
- Chicken
- Mammalian Cells
- Wheat Germ
- E.coli
- HEK293
- In Vitro Cell Free System
- His
- Non
- GST
- Avi
- Fc
- DDK
- Myc
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| RPL12-11566Z | Recombinant Zebrafish RPL12 | Mammalian Cells | Zebrafish | His |
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| RPL12-14407M | Recombinant Mouse RPL12 Protein | Mammalian Cells | Mouse | His |
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| RPL12-31150TH | Recombinant Human RPL12 | Wheat Germ | Human | Non | 165 amino acids |
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| RPL12-3972R | Recombinant Rhesus monkey RPL12 Protein, His-tagged | Mammalian Cells | Rhesus macaque | His |
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| RPL12-5056C | Recombinant Chicken RPL12 | Mammalian Cells | Chicken | His |
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| RPL12-7529H | Recombinant Human RPL12, His-tagged | E.coli | Human | His | 1-165aa |
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| RPL12-2227HCL | Recombinant Human RPL12 293 Cell Lysate | HEK293 | Human | Non |
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| RPL12-301606H | Recombinant Human RPL12 protein, GST-tagged | E.coli | Human | GST | Met1-Ser165 |
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| RPL12-3789R | Recombinant Rhesus Macaque RPL12 Protein, His (Fc)-Avi-tagged | HEK293 | Rhesus macaque | Avi&Fc&His |
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| RPL12-3789R-B | Recombinant Rhesus Macaque RPL12 Protein Pre-coupled Magnetic Beads | HEK293 | Rhesus macaque |
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| RPL12-446HF | Recombinant Full Length Human RPL12 Protein | In Vitro Cell Free System | Human | Full L. 165 amino acids |
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| Rpl12-5584M | Recombinant Mouse Rpl12 Protein, Myc/DDK-tagged | HEK293 | Mouse | DDK&Myc |
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| RPL12-7722M | Recombinant Mouse RPL12 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | Avi&Fc&His |
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| RPL12-7722M-B | Recombinant Mouse RPL12 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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| RPL12-883H | Recombinant Human RPL12 Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293 | Human | DDK&Myc |
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Involved Pathway
RPL12 involved in several pathways and played different roles in them. We selected most pathways RPL12 participated on our site, such as Ribosome, which may be useful for your reference. Also, other proteins which involved in the same pathway with RPL12 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Ribosome | RPS10,RPL34-PS1,RPL36A,RPL28,UBA52,RPS13,RPLP2,RPL23A,RPL31,MRPS10 |
Protein Function
RPL12 has several biochemical functions, for example, poly(A) RNA binding,protein binding,rRNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by RPL12 itself. We selected most functions RPL12 had, and list some proteins which have the same functions with RPL12. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| structural constituent of ribosome | MRPL46,MRPS31,MRPS9,RPL4,RPL31,FAUA,MRPS18C,RPS21,MRPL41,MRPL10 |
| rRNA binding | MRPL11,RPS4Y1,MTERFD2,RPS18,DIEXF,NOL12,RPF2,ANG,RPL11,DDX28 |
| protein binding | PBX4,STRADA,GSK3A,PLGRKT,INTS12,BAIAP2,TFAP2B,MAT2A,HDC,PSMA2 |
| poly(A) RNA binding | PFN1,RPP25L,CNOT1,ZC3H15,CCDC108,RPS13,H2-Q10,HIST1H1C,ZNFX1,C1orf53 |
Interacting Protein
RPL12 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with RPL12 here. Most of them are supplied by our site. Hope this information will be useful for your research of RPL12.
CANX;ZNF16;TUBA4A;CBX1;TTN;UBE2O;midostaurin;NOP56;GABARAP;FN1;ESR1;US11;VIM;VCAM1;RPL10
Resources
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References
- Delage, L; Giege, P; et al. Four paralogues of RPL12 are differentially associated to ribosome in plant mitochondria. BIOCHIMIE 89:658-668(2007).
- SCHMIDT, J; BUBUNENKO, M; et al. A NOVEL OPERON ORGANIZATION INVOLVING THE GENES FOR CHORISMATE SYNTHASE (AROMATIC BIOSYNTHESIS PATHWAY) AND RIBOSOMAL GTPASE CENTER PROTEINS (L11, L1, L10, L12-RPLKAJL) IN CYANOBACTERIUM SYNECHOCYSTIS PCC 6803. JOURNAL OF BIOLOGICAL CHEMISTRY 268:27447-27457(1993).
- CRITTEND.LB; OKAZAKI, W; et al. GENETIC INFLUENCE OF RS LOCUS ON SUSCEPTIBILITY TO AVIAN TUMOR VIRUSES .2. ROUS SARCOMA VIRUS ANTIBODY PRODUCTION AFTER STRAIN RPL12 VIRUS INOCULATION. JOURNAL OF THE NATIONAL CANCER INSTITUTE 36:299-&(1966).
