RPL14
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Official Full Name
ribosomal protein L14 -
Overview
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L14E family of ribosomal proteins. It contains a basic region-leucine zipper (bZIP)-like domain. The protein is located in the cytoplasm. This gene contains a trinucleotide (GCT) repeat tract whose length is highly polymorphic; these triplet repeats result in a stretch of alanine residues in the encoded protein. Transcript variants utilizing alternative polyA signals and alternative 5-terminal exons exist but all encode the same protein. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. -
Synonyms
RPL14;ribosomal protein L14;60S ribosomal protein L14;CAG ISL 7;CTG B33;hRL14;L14;RL14;CTG-B33;CAG-ISL-7;MGC88594
Recombinant Proteins
- Human
- Mouse
- T.gondii
- Zebrafish
- E.coli
- Mammalian Cells
- E.Coli/Yeast
- HEK293
- GST
- His
- Non
- DDK
- Myc
- Avi
- Fc
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| RPL14-2377H | Recombinant Human RPL14, GST-tagged | E.coli | Human | GST | 1-216aa | |
| RPL14-14410M | Recombinant Mouse RPL14 Protein | Mammalian Cells | Mouse | His |
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| RPL14-818T | Recombinant Toxoplasma gondii RH (strain: RH) RPL14 protein, His-tagged | E.Coli/Yeast | T.gondii | His |
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| RPL14-854Z | Recombinant Zebrafish RPL14 | Mammalian Cells | Zebrafish | His |
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| RPL14-2223HCL | Recombinant Human RPL14 293 Cell Lysate | HEK293 | Human | Non |
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| RPL14-2224HCL | Recombinant Human RPL14 293 Cell Lysate | HEK293 | Human | Non |
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| RPL14-2988H | Recombinant Human RPL14 Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293 | Human | DDK&Myc |
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| RPL14-5142H | Recombinant Human RPL14 protein, GST-tagged | E.coli | Human | GST | 2-214aa |
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| Rpl14-5586M | Recombinant Mouse Rpl14 Protein, Myc/DDK-tagged | HEK293 | Mouse | DDK&Myc |
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| RPL14-7725M | Recombinant Mouse RPL14 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | Avi&Fc&His |
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| RPL14-7725M-B | Recombinant Mouse RPL14 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
RPL14 involved in several pathways and played different roles in them. We selected most pathways RPL14 participated on our site, such as Ribosome, which may be useful for your reference. Also, other proteins which involved in the same pathway with RPL14 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Ribosome | RPL7A,MRPL30,MRPL14,RPS16,RPL23A,RPS27.1,RPS29,MRPL16,RPL36,RPS7 |
Protein Function
RPL14 has several biochemical functions, for example, RNA binding,poly(A) RNA binding,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by RPL14 itself. We selected most functions RPL14 had, and list some proteins which have the same functions with RPL14. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| structural constituent of ribosome | RPL5B,RPLP0,RPS27.2,RPL8,RPLP2,RPS13,RPL37A,SLC25A38A,RPS3A,RPL10L |
| RNA binding | FAU,RNASEL4,ETF1,SRSF10,DAZL,RNMTL1B,THOC6,EIF4H,LARP6,PDCD11 |
| poly(A) RNA binding | HDAC2,GPATCH4,BAG4,ISY1,FASTKD3,HIST1H4A,NVL,ZFP326,SCAF4,MRPL20 |
| protein binding | EXD1,ZFP523,ZWINT,NIP7,RPS10,PEX1,LATS1,SLC4A4,ERGIC1,TLE4 |
Interacting Protein
RPL14 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with RPL14 here. Most of them are supplied by our site. Hope this information will be useful for your research of RPL14.
VCAM1;LRRK2;PHLDA1;ESR1;MAP3K1;MAP3K14;KLF10;UBE2E3;TLE6;KCNK4;midostaurin;Srp72;Smad6
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References
- Soung, GY; Miller, JL; et al. Comprehensive Analysis of Phosphorylated Proteins of Escherichia coli Ribosomes. JOURNAL OF PROTEOME RESEARCH 8:3390-3402(2009).
- Gonzalez, AC; Thomas, MC; et al. Molecular and immunological characterization of L14 ribosomal protein from Leishmania braziliensis. PARASITOLOGY 128:139-147(2004).
