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RPL14

Official Full Name

ribosomal protein L14
Overview

Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L14E family of ribosomal proteins. It contains a basic region-leucine zipper (bZIP)-like domain. The protein is located in the cytoplasm. This gene contains a trinucleotide (GCT) repeat tract whose length is highly polymorphic; these triplet repeats result in a stretch of alanine residues in the encoded protein. Transcript variants utilizing alternative polyA signals and alternative 5-terminal exons exist but all encode the same protein. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.
Synonyms

RPL14; ribosomal protein L14; 60S ribosomal protein L14; CAG ISL 7; CTG B33; hRL14; L14; RL14; CTG-B33; CAG-ISL-7; MGC88594;

Type

Recombinant Proteins
Cell & Tissue Lysates
Protein Pre-coupled Magnetic Beads

Species

Human
Mouse
Toxoplasma gondii RH (strain: RH)
Zebrafish

Source

E. coli or Yeast
E.coli
HEK293
HEK293T
Mammalian Cell

Tag

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	RPL14-2377H	Recombinant Human RPL14, GST-tagged	E.coli	GST	1-216aa	$319 / 25μg
Human	RPL14-2223HCL	Recombinant Human RPL14 293 Cell Lysate	HEK293	Non		Inquiry
Human	RPL14-2224HCL	Recombinant Human RPL14 293 Cell Lysate	HEK293	Non		Inquiry
Human	RPL14-5142H	Recombinant Human RPL14 protein, GST-tagged	E.coli	GST	2-214aa	Inquiry
Human	RPL14-2988H	Recombinant Human RPL14 Protein, Myc/DDK-tagged, C13 and N15-labeled	HEK293T	Myc&DDK		Inquiry
Mouse	RPL14-14410M	Recombinant Mouse RPL14 Protein	Mammalian Cell	His		Inquiry
Mouse	RPL14-7725M-B	Recombinant Mouse RPL14 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Mouse	Rpl14-5586M	Recombinant Mouse Rpl14 Protein, Myc/DDK-tagged	HEK293T	Myc&DDK		Inquiry
Mouse	RPL14-7725M	Recombinant Mouse RPL14 Protein, His (Fc)-Avi-tagged	HEK293	His&Fc&Avi		Inquiry
Toxoplasma gondii RH (strain: RH)	RPL14-818T	Recombinant Toxoplasma gondii RH (strain: RH) RPL14 protein, His-tagged	E. coli or Yeast	His		Inquiry
Zebrafish	RPL14-854Z	Recombinant Zebrafish RPL14	Mammalian Cell	His		Inquiry

Involved Pathway
Protein Function
Interacting Protein
Other Resource

RPL14 involved in several pathways and played different roles in them. We selected most pathways RPL14 participated on our site, such as Ribosome, which may be useful for your reference. Also, other proteins which involved in the same pathway with RPL14 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Ribosome	RPL28;RPL7A;RPL22;MRPS6;RPS14;RPLP2;RPL23;FAU;RPS17

RPL14 has several biochemical functions, for example, RNA binding, poly(A) RNA binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by RPL14 itself. We selected most functions RPL14 had, and list some proteins which have the same functions with RPL14. You can find most of the proteins on our site.

Function	Related Protein
RNA binding	SMN1;CTIF;BICC2;CSTF2;RPL26;TUT1;DNAJC17;ZMAT4;PAPOLA
poly(A) RNA binding	EIF1AX;DDX10;MRPS14;RTCD1;PURB;TIA1;RBM12B1;ATXN2;RBPMS
protein binding	CHRAC1;CCNF;SLC9A1;SGOL1;AMY1A;CHPF;NACC2;PTPN11A;DNAJC11
structural constituent of ribosome	MRPL13;RPS4Y2;MRPS2;RPL37A;RPL29;RPS14;MRPS9;RPL15;RPS19

RPL14 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with RPL14 here. Most of them are supplied by our site. Hope this information will be useful for your research of RPL14.

VCAM1; LRRK2; PHLDA1; ESR1; MAP3K1; MAP3K14; KLF10; UBE2E3; TLE6; KCNK4; midostaurin; Srp72; Smad6

Research Area

Soung, GY; Miller, JL; et al. Comprehensive Analysis of Phosphorylated Proteins of Escherichia coli Ribosomes. JOURNAL OF PROTEOME RESEARCH 8:3390-3402(2009).

Gonzalez, AC; Thomas, MC; et al. Molecular and immunological characterization of L14 ribosomal protein from Leishmania braziliensis. PARASITOLOGY 128:139-147(2004).