Recombinant Human ATG4C, GST-tagged

• Cat.No.: ATG4C-9976H
• Product Overview: Recombinant Human ATG4C protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.

Specification

• Description: Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. This gene encodes a member of the autophagin protein family. The encoded protein is also designated as a member of the C-54 family of cysteine proteases. Alternate transcriptional splice variants, encoding the same protein, have been characterized.
• Source: E.coli
• Species: Human
• Tag: GST
• Protein length: 1-300a.a.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.

Gene Information

• Gene Name: ATG4C ATG4 autophagy related 4 homolog C (S. cerevisiae) [ Homo sapiens ]
• Official Symbol: ATG4C
• Synonyms: ATG4C; ATG4 autophagy related 4 homolog C (S. cerevisiae); APG4 autophagy 4 homolog C (S. cerevisiae) , APG4C, AUT (S. cerevisiae) like 1, cysteine endopeptidase; AUT like 1, cysteine endopeptidase (S. cerevisiae) , AUTL1; cysteine protease ATG4C; AUTL3; FLJ14867; autophagin-3; APG4 autophagy 4 homolog C; AUT-like 3 cysteine endopeptidase; AUT-like 1, cysteine endopeptidase; autophagy-related protein 4 homolog C; autophagy-related cysteine endopeptidase 3; APG4C; AUTL1; APG4-C
• Gene ID: 84938
• mRNA Refseq: NM_032852
• Protein Refseq: NP_116241
• MIM: 611339
• UniProt ID: Q96DT6
• Chromosome Location: 1p31.3
• Pathway: Regulation of autophagy, organism-specific biosystem; Regulation of autophagy, conserved biosystem
• Function: cysteine-type endopeptidase activity; peptidase activity