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Official Full Name ATG3 autophagy related 3 homolog
Background Autophagy is a process of bulk degradation of cytoplasmic components by the lysosome or vacuole. Human ATG3 displays;the same enzymatic characteristics in vitro as yeast Apg3, a protein-conjugating enzyme essential for autophagy;(Tanida et al., 2002 (PubMed 11825910)).
Synonyms ATG3; ATG3 autophagy related 3 homolog (S. cerevisiae); APG3 autophagy 3 like (S. cerevisiae) , APG3L; ubiquitin-like-conjugating enzyme ATG3; DKFZp564M1178; FLJ22125; MGC15201; PC3 96; hApg3; 2610016C12Rik; autophagy-related protein 3; APG3; APG3L; PC3-9
    • Species :
    • Chicken
    • Human
    • Mouse
    • Rat
    • Rhesus Macaque
    • Zebrafish
    • Source :
    • E.coli
    • HEK293
    • HEK293T
    • Mammalian Cell
    • Mouse
    • Wheat Germ
    • Tag :
    • GST
    • His
    • Myc/DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human ATG3-1816H Recombinant Human ATG3 protein, GST-tagged E.coli GST
    Human APG3L-678H Recombinant Human APG3L protein, GST-tagged Wheat Germ GST
    Human ATG3-222H Recombinant Human ATG3, His-tagged E.coli His
    Human ATG3-3031H Recombinant Human ATG3 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Human ATG3-35H Recombinant Human ATG3, His-tagged E.coli His
    Human ATG3-744H Recombinant Human ATG3 Protein, His-tagged E.coli His
    Human ATG3-8625HCL Recombinant Human ATG3 293 Cell Lysate HEK293 N/A
    Human ATG3-947H Recombinant Human ATG3 protein, GST-tagged Wheat Germ GST
    Human DMABT-H17736 Mouse Anti-Atg3 Monoclonal Antibody Mouse N/A
    Mouse Atg3-1759M Recombinant Mouse Atg3 Protein, Myc/DDK-tagged HEK293T Myc/DDK
    Mouse ATG3-2081M Recombinant Mouse ATG3 Protein Mammalian Cell His
    Rat ATG3-844R Recombinant Rat ATG3 Protein Mammalian Cell His
    Rhesus Macaque ATG3-440R Recombinant Rhesus monkey ATG3 Protein, His-tagged Mammalian Cell His
    Chicken ATG3-5340C Recombinant Chicken ATG3 Mammalian Cell His
    Zebrafish ATG3-10381Z Recombinant Zebrafish ATG3 Mammalian Cell His

    ATG3 involved in several pathways and played different roles in them. We selected most pathways ATG3 participated on our site, such as Regulation of autophagy, which may be useful for your reference. Also, other proteins which involved in the same pathway with ATG3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Regulation of autophagy ULK2; IFNA13; ATG3; INSB; IFNPHI1; PRKAA1; IFNA1; Ifna11; PIK3C3; PIK3R4

    ATG3 has several biochemical functions, for example, Atg12 transferase activity, Atg8 ligase activity, enzyme binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ATG3 itself. We selected most functions ATG3 had, and list some proteins which have the same functions with ATG3. You can find most of the proteins on our site.

    Function Related Protein
    Atg12 transferase activity ATG3; ATG10
    Atg8 ligase activity ATG3; ATG12
    enzyme binding GSTM3; MAPK8; LAMB1; SNRPD3; GNB2L1; HSPA2; RXRA; AXIN1; RPS2; YWHAE
    ligase activity RNF181; ATG10; RFWD3; TRIM38; TRAIP; CCNB1IP1; TRIM27; TTLL11; RNF180; RNF213
    protein binding NDC80; NUPL1; JAK2; NINJ2; TNFAIP8L1; CEP350; CPS1; Casp3; C10orf35; FAM46B
    ubiquitin-like protein transferase activity ATG16L1; ARIH1; UBL4A; RNF14; ATG3; RNF139

    ATG3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ATG3 here. Most of them are supplied by our site. Hope this information will be useful for your research of ATG3.


    Kamat, PK; Kalani, A; et al. Hydrogen Sulfide Epigenetically Attenuates Homocysteine-Induced Mitochondrial Toxicity Mediated Through NMDA Receptor in Mouse Brain Endothelial (bEnd3) Cells. JOURNAL OF CELLULAR PHYSIOLOGY 230:378-394(2015).
    Akl, MR; Ayoub, NM; et al. Araguspongine C Induces Autophagic Death in Breast Cancer Cells through Suppression of c-Met and HER2 Receptor Tyrosine Kinase Signaling. MARINE DRUGS 13:288-311(2015).

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