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Official Full Name ATG7 autophagy related 7 homolog (S. cerevisiae)
Background This gene was identified based on homology to Pichia pastoris GSA7 and Saccharomyces cerevisiae APG7. In the yeast, the protein appears to be required for fusion of peroxisomal and vacuolar membranes. The protein shows homology to the ATP-binding and catalytic sites of the E1 ubiquitin activating enzymes.
Synonyms ATG7; ATG7 autophagy related 7 homolog (S. cerevisiae); GSA7; APG7L; APG7-LIKE; DKFZp434N0735; APG7 autophagy 7-like (S. cerevisiae); Ubiquitin-like modifier-activating enzyme ATG7; ATG12-activating enzyme E1 ATG7; Autophagy-related protein 7; hAGP7; Ubiquitin-activating enzyme E1-like protein; OTTHUMP00000160157; OTTHUMP00000207591; OTTHUMP00000207592; ubiquitin activating enzyme E1-like protein
    • Species :
    • Chicken
    • Human
    • Mouse
    • Rat
    • Rhesus Macaque
    • Source :
    • E. coli
    • E.coli
    • HEK293
    • HEK293T
    • Insect Cell
    • Mammalian Cell
    • Sf21 Insect Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • Myc/DDK
    • Myc
    • DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human APG7L-680H Recombinant Human APG7L protein, GST-tagged Wheat Germ GST
    Human ATG7-1076H Recombinant Human ATG7 Protein, His-tagged Sf21 Insect Cell His
    Human ATG7-127H Recombinant Human full-length ATG7, GST-tagged Wheat Germ GST
    Human ATG7-128H Recombinant Human ATG7, MYC/DDK-tagged HEK293 Myc/DDK
    Human ATG7-169H Recombinant Human ATG7, His-tagged Insect Cell His
    Human ATG7-5180H Recombinant Human ATG7 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Human ATG7-8621HCL Recombinant Human ATG7 293 Cell Lysate HEK293 N/A
    Mouse Atg7-1524M Recombinant Mouse Atg7 Protein, His-tagged E.coli His
    Mouse Atg7-1525M Recombinant Mouse Atg7 Protein, His-tagged E. coli His
    Mouse Atg7-1762M Recombinant Mouse Atg7 Protein, Myc/DDK-tagged HEK293T Myc/DDK
    Rat ATG7-845R Recombinant Rat ATG7 Protein Mammalian Cell His
    Rhesus Macaque ATG7-443R Recombinant Rhesus monkey ATG7 Protein, His-tagged Mammalian Cell His
    Chicken ATG7-2305C Recombinant Chicken ATG7 Mammalian Cell His

    Atg7 involved in several pathways and played different roles in them. We selected most pathways Atg7 participated on our site, such as Adaptive Immune System, Antigen processing: Ubiquitination &amp, Proteasome degradation, which may be useful for your reference. Also, other proteins which involved in the same pathway with Atg7 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Adaptive Immune System ASB6; PTBP3; CD300LG; KIF20A; SH2D1B; KLRF1; CD226; LILRB1; RNF34; RNF111
    Antigen processing: Ubiquitination &amp RNF111; ASB17; HUWE1; WWP1; TRIM69; RNF41; RNF14; DZIP3; ARIH2; BLMH
    Proteasome degradation TRIM11; RNF6; VPRBP; ASB14; ASB8; ASB6; RNF41; SPSB4; TRIM69; TPP2
    Cellular responses to stress CHMP4C; SUZ12A; LC3; EP400; HMGA1B; EEF1A1; HSBP1; HDAC6; LAMTOR1; TXNRD2
    Class I MHC mediated antigen processing &amp RNF138; ASB8; CMTM2A; UBE2U; RBCK1; ARIH2; PJA1; TRIM9; RNF19B; HECTD3
    presentation UBE2V2; ASB2; ASB7; ASB13; ERAP1; UBE2F; RNF111; SPSB1; DZIP3; TRIM50
    Immune System CFHL3; CMTM2A; BTR18; KIF11; DHX9; TNRC5; DEFB4B; IFIT10; NPEPPS; TRIM14
    Macroautophagy LC3; ATG7; DYNLL2B; ULK1A; AMBRA1A; AMBRA1B; WDR45; AMBRA1; UVRAG; MAP1LC3C
    Regulation of autophagy ATG3; ATG13; INS1; GABARAPL2; INSB; IFNA17; IFNPHI3; IFNA14; PIK3C3; Ifna11
    Senescence and Autophagy ING1; FKBP8; LC3; GABARAP; IFI16; SLC39A2; MAP1LC3B; AMBRA1; SLC39A1; IGFBP7

    Atg7 has several biochemical functions, for example, Atg12 activating enzyme activity, Atg8 activating enzyme activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by Atg7 itself. We selected most functions Atg7 had, and list some proteins which have the same functions with Atg7. You can find most of the proteins on our site.

    Function Related Protein
    Atg12 activating enzyme activity ATG7
    Atg8 activating enzyme activity ATG7
    protein binding SPRED1; IMP3; FAM98A; WRNIP1; CSF2; RASL10B; AMPH; MTERFD2; GOLGA1; PAX5
    protein homodimerization activity RPE; MAP3K11; TFAP2E; PON1; RAB11FIP4A; ACAT1; UGT1A7; MCL1B; APOBEC3G; LGALS1
    transcription factor binding NLRP3; CD34; YWHAZ; PIAS2; MECP2; ATOH8; PPARGC1A; KDM1A; CREBBP; MAPK1
    ubiquitin activating enzyme activity UBE1Y1; ATG7; UBA1; UBA7; SAE1; UBA6

    Atg7 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Atg7 here. Most of them are supplied by our site. Hope this information will be useful for your research of Atg7.


    Okada, M; Oikawa, M; et al. Immunohistochemical assessment of ATG7, LC3, and p62 in ameloblastomas. JOURNAL OF ORAL PATHOLOGY & MEDICINE 43:606-612(2014).
    Chen, M; Hong, MJ; et al. Essential role for autophagy in the maintenance of immunological memory against influenza infection. NATURE MEDICINE 20:507-514(2014).

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