ATG5

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ATG5

Official Full Name autophagy related 5
Background Required for autophagy. Conjugates to ATG12 and associates with isolation membrane to form cup-shaped isolation membrane and autophagosome. The conjugate detaches from the membrane immediately before or after autophagosome formation is completed.<br/>May play an important role in the apoptotic process, possibly within the modified cytoskeleton. Its expression is a relatively late event in the apoptotic process, occurring downstream of caspase activity.
Synonyms ATG5; autophagy related 5; ASP; APG5; APG5L; hAPG5; APG5-LIKE; autophagy protein 5; apoptosis-specific protein; ATG5 autophagy related 5 homolog;
    • Species :
    • Chicken
    • Human
    • Mouse
    • Zebrafish
    • Source :
    • E. coli
    • E.coli
    • HEK293
    • HEK293T
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • MYC/DDK
    • N/A
    • T7
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human ATG5-020H Recombinant Human ATG5 Protein, His-tagged E. coli His
    Human APG5L-679H Recombinant Human APG5L protein, GST-tagged Wheat Germ GST
    Human ATG5-174H Recombinant Human ATG5 protein, T7-tagged E.coli T7
    Human ATG5-18H Recombinant Human ATG5 Protein, His-tagged E.coli His
    Human ATG5-26988TH Recombinant Human ATG5, T7 -tagged E.coli T7
    Human ATG5-3425H Recombinant Human ATG5, His-tagged E.coli His
    Human ATG5-5279H Recombinant Human ATG5 Autophagy Related 5 Homolog (S. cerevisiae), T7-tagged E.coli T7
    Human ATG5-543H Recombinant Human ATG5 Protein E.coli N/A
    Human ATG5-73H Recombinant Human ATG5 Autophagy Related 5 Homolog, T7-tagged E.coli T7
    Human ATG5-8622HCL Recombinant Human ATG5 293 Cell Lysate HEK293 N/A
    Human ATG5-951H Recombinant Human ATG5 protein, GST-tagged Wheat Germ GST
    Mouse ATG5-2085M Recombinant Mouse ATG5 Protein Mammalian Cell His
    Mouse Atg5-624M Recombinant Mouse Atg5 Protein, MYC/DDK-tagged HEK293T MYC/DDK
    Chicken ATG5-1551C Recombinant Chicken ATG5 Mammalian Cell His
    Zebrafish ATG5-1983Z Recombinant Zebrafish ATG5 Mammalian Cell His

    ATG5 involved in several pathways and played different roles in them. We selected most pathways ATG5 participated on our site, such as Regulation of autophagy, RIG-I-like receptor signaling pathway, Shigellosis, which may be useful for your reference. Also, other proteins which involved in the same pathway with ATG5 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Regulation of autophagy ULK3; IFNA8; ATG4D; ATG5; ATG12; PRKAA2; IFNA2; IFNA4; IFNA1; IFNG
    RIG-I-like receptor signaling pathway DDX3; MAPK12; FADD; IFNA14; MAPK8; IFIH1; DDX58; OTUD5A; IFNPHI1; IKBKE
    Shigellosis PFN4; ACTG1; PFN3; NFKBIB; MAPK12; IL-8; ACTB; ATG5; IKBKB; CDC42

    ATG5 has several biochemical functions, for example, contributes_to Atg8 ligase activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ATG5 itself. We selected most functions ATG5 had, and list some proteins which have the same functions with ATG5. You can find most of the proteins on our site.

    Function Related Protein
    contributes_to Atg8 ligase activity ATG5
    protein binding HIST1H3D; ERAP1; GP5; LGI4; BCAR1; RFPL4; FRMD7; DHX32; KLHDC4; ADAMTSL5

    ATG5 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ATG5 here. Most of them are supplied by our site. Hope this information will be useful for your research of ATG5.

    ATG12; WDFY3; ATG16L1; GABARAP; MAP1LC3B

    Cai, PP; Wang, HX; et al. Variants of autophagy-related gene 5 are associated with neuromyelitis optica in the Southern Han Chinese population. AUTOIMMUNITY 47:563-566(2014).
    Cenci, S; et al. Autophagy, a new determinant of plasma cell differentiation and antibody responses. MOLECULAR IMMUNOLOGY 62:289-295(2014).

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