atg16l1
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  • Official Full Name
  • autophagy related 16-like 1 (S. cerevisiae)
  • Background
  • The protein encoded by this gene is part of a large protein complex that is necessary for autophagy, the major process by which intracellular components are targeted to lysosomes for degradation. Defects in this gene are a cause of susceptibility to inflammatory bowel disease type 10 (IBD10). Several transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Jun 2010]
  • Synonyms
  • ATG16L1; autophagy related 16-like 1 (S. cerevisiae); IBD10; WDR30; APG16L; ATG16A; ATG16L; autophagy-related protein 16-1; APG16L beta; WD repeat domain 30; ATG16 autophagy related 16-like 1;
Cat.#:ATG16L1-2947HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human ATG16L1 Protein, His-tagged
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Cat.#:ATG16L1-1469HTag:His/GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human ATG16L1 protein, His & GST-tagged
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Cat.#:ATG16L1-1470HTag:His/T7
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human ATG16L1 protein, His & T7-tagged
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Cat.#:ATG16L1-945HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human ATG16L1 protein, GST-tagged
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Cat.#:ATG16L1-439RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey ATG16L1 Protein, His-tagged
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Cat.#:ATG16L1-2577ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish ATG16L1
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Cat.#:ATG16L1-146HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human ATG16L1 cell lysate
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Involved Pathway

ATG16L1 involved in several pathways and played different roles in them. We selected most pathways ATG16L1 participated on our site, such as Regulation of autophagy, which may be useful for your reference. Also, other proteins which involved in the same pathway with ATG16L1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Regulation of autophagy
GABARAPL2; IFNA1; ULK2; ATG16L1; IFNA5; ATG14; Ifna15; IFNG; INSB; ULK3

Protein Function

ATG16L1 has several biochemical functions, for example, identical protein binding, protein binding, ubiquitin-like protein transferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by ATG16L1 itself. We selected most functions ATG16L1 had, and list some proteins which have the same functions with ATG16L1. You can find most of the proteins on our site.
Function
Related Protein
Function identical protein binding
Related Protein UGP2; KCNIP2; VPS4B; PRDX3; LDHB; CALHM1; NDC80; CLDN23; SYP; CCDC155
Function protein binding
Related Protein SNX33; ASAP3; LGALS8; PCBD2; TMED2; FMO4; FBL; PKP2; GOLPH3L; HADHA
Function ubiquitin-like protein transferase activity
Related Protein ATG3; RNF14; RNF139; UBL4A; ATG16L1; ARIH1

Interacting Protein

ATG16L1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ATG16L1 here. Most of them are supplied by our site. Hope this information will be useful for your research of ATG16L1.
RB1CC1; ATG5; ATG12; MAP1LC3C; TMEM59

ATG16L1 Related Articles

Ciccacci, C; Perricone, C; et al. A Multilocus Genetic Study in a Cohort of Italian SLE Patients Confirms the Association with STAT4 Gene and Describes a New Association with HCP5 Gene. PLOS ONE 9:-(2014).
Lee, KM; Lee, JM; et al. Crohn's disease in Korea: past, present, and future. KOREAN JOURNAL OF INTERNAL MEDICINE 29:558-570(2014).