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ATG4A

  • Official Full Name

    ATG4 autophagy related 4 homolog A

  • Overview

    Autophagy is a catabolic process for the autophagosomic-lysosomal degradation of bulk cytoplasmic contents. Control of autophagy was largely discovered in yeast and involves proteins encoded by a set of autophagy-related genes (Atg) (1). Formation of auto
  • Synonyms

    ATG4A; ATG4 autophagy related 4 homolog A (S. cerevisiae); APG4 autophagy 4 homolog A (S. cerevisiae) , APG4A, AUT like 2, cysteine endopeptidase (S. cerevisiae) , AUTL2; cysteine protease ATG4A; hAPG4A; autophagin 2; autophagin-2; APG4 autophagy 4 homol;

  • Recombinant Proteins
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Rhesus Macaque
  • Zebrafish
  • E.coli
  • HEK293
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human ATG4A-36H Recombinant Human ATG4A, His-tagged E.coli His
Human ATG4A-948H Recombinant Human ATG4A protein, GST-tagged Wheat Germ GST
Human ATG4A-1512HF Recombinant Full Length Human ATG4A Protein, GST-tagged In Vitro Cell Free System GST 398 amino acids
Rhesus Macaque ATG4A-441R Recombinant Rhesus monkey ATG4A Protein, His-tagged Mammalian Cell His
Rhesus Macaque ATG4A-270R-B Recombinant Rhesus Macaque ATG4A Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque ATG4A-270R Recombinant Rhesus Macaque ATG4A Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Zebrafish ATG4A-3034Z Recombinant Zebrafish ATG4A Mammalian Cell His
Chicken ATG4A-4696C Recombinant Chicken ATG4A Mammalian Cell His
Chicken ATG4A-4695C Recombinant Chicken ATG4A Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • ATG4A Related Articles
  • ATG4A Related Research Area

ATG4A involved in several pathways and played different roles in them. We selected most pathways ATG4A participated on our site, such as Cellular responses to stress, Macroautophagy, Regulation of autophagy, which may be useful for your reference. Also, other proteins which involved in the same pathway with ATG4A were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Cellular responses to stressTERF2;RING1;DPF1;ACD;HIRA;DYNLL2A;TERF2IP;HTATIP;HDAC6
MacroautophagyATG9B;RB1CC1;ATG101;MAP1LC3B;ULK1A;GABARAPL2;ATG7;AMBRA1B;DYNLL2A
Regulation of autophagyIFNA1;INSB;ATG4B;GABARAPL1;ATG5;IFNA16;IFNPHI3;ULK1;Ifna11

ATG4A has several biochemical functions, for example, cysteine-type endopeptidase activity, cysteine-type peptidase activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ATG4A itself. We selected most functions ATG4A had, and list some proteins which have the same functions with ATG4A. You can find most of the proteins on our site.

Function Related Protein
cysteine-type endopeptidase activityUSP22;CTSH;USP17L5;LGMN;USP28;USP30;FAM49BA;CTSC;USP8
cysteine-type peptidase activityCTSL.1;CTSSA;CAPN1A;CASPC;CTSSB.1;CAPN1B;GM12824;FAM49BA;ALG13
protein bindingHNRNPUL1;SUB1;EIF4G2;MT1F;GATA2;KNG1;PTPRG;CTSZ;IPO13

ATG4A has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ATG4A here. Most of them are supplied by our site. Hope this information will be useful for your research of ATG4A.

CDKL3; GABARAPL1; MAP1LC3B; SYN1; PDK1; USP43; THOC1; NUF2; MAP1LC3A

Fan, JD; Lei, PJ; et al. The Selective Activation of p53 Target Genes Regulated by SMYD2 in BIX-01294 Induced Autophagy-Related Cell Death. PLOS ONE 10:-(2015).
Liao, YP; Chen, LY; et al. Hypomethylation signature of tumor-initiating cells predicts poor prognosis of ovarian cancer patients. HUMAN MOLECULAR GENETICS 23:1894-1906(2014).
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