ATG10

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ATG10

Official Full Name autophagy related 10
Background Autophagy is a process for the bulk degradation of cytosolic compartments by lysosomes. ATG10 is an E2-like enzyme involved in 2 ubiquitin-like modifications essential for autophagosome formation: ATG12 (MIM 609608)-ATG5 (MIM 604261) conjugation and modification of a soluble form of MAP-LC3 (MAP1LC3A; MIM 601242), a homolog of yeast Apg8, to a membrane-bound form (Nemoto et al., 2003 [PubMed 12890687]).[supplied by OMIM, Mar 2008]
Synonyms ATG10; autophagy related 10; APG10; APG10L; pp12616; ubiquitin-like-conjugating enzyme ATG10; autophagy-related protein 10; ATG10 autophagy related 10 homolog;
    • Species :
    • Human
    • Mouse
    • Zebrafish
    • Source :
    • E.coli
    • HEK293
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human ATG10-7174H Recombinant Human ATG10 Autophagy Related 10 Homolog (S. cerevisiae), His-tagged E.coli His
    Human ATG10-8627HCL Recombinant Human ATG10 293 Cell Lysate HEK293 N/A
    Human ATG10-942H Recombinant Human ATG10 protein, GST-tagged Wheat Germ GST
    Human ATG10-9968H Recombinant Human ATG10, GST-tagged E.coli GST
    Mouse ATG10-2073M Recombinant Mouse ATG10 Protein Mammalian Cell His
    Zebrafish ATG10-3489Z Recombinant Zebrafish ATG10 Mammalian Cell His

    ATG10 involved in several pathways and played different roles in them. We selected most pathways ATG10 participated on our site, such as Regulation of autophagy, which may be useful for your reference. Also, other proteins which involved in the same pathway with ATG10 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Regulation of autophagy IFNA7; ATG10; IFNA1; IFNG; ULK3; ULK1; IFNA16; GABARAPL1; INS; IFNG1-2

    ATG10 has several biochemical functions, for example, Atg12 transferase activity, ligase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by ATG10 itself. We selected most functions ATG10 had, and list some proteins which have the same functions with ATG10. You can find most of the proteins on our site.

    Function Related Protein
    Atg12 transferase activity ATG10; ATG3
    ligase activity RNF168; TRIM6; RBX1; SIAH2L; TRIM31; TRIM2; PELI2; TRIM5; UBE2D1A; ZFP91

    ATG10 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ATG10 here. Most of them are supplied by our site. Hope this information will be useful for your research of ATG10.

    GABARAP; GABARAPL2; MAP1LC3C; MAP1LC3B; GABARAPL1; MAP1LC3B2; HAT1; ATG12; ATG7; MAP1B; USP11; RBBP7; USP7; ATG3; ATG4B; q81sn0_bacan

    Pulliero, A; Seydel, A; et al. Oxidative Damage and Autophagy in the Human Trabecular Meshwork as Related with Ageing. PLOS ONE 9:-(2014).
    Zhang, LS; Zhang, J; et al. Autophagy in Pancreatic Acinar Cells in Caerulein-treated Mice: Immunolocalization of Related Proteins and Their Potential as Markers of Pancreatitis. TOXICOLOGIC PATHOLOGY 42:435-457(2014).

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