Recombinant Human FBXO18, His-tagged
Cat.No. : | FBXO18-12787H |
Product Overview : | Recombinant Human FBXO18 protein, fused to His-tag, was expressed in E.coli and purified by Ni-sepharose. |
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Description : | This gene encodes a member of the F-box protein family, members of which are characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into three classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbx class. It contains an F-box motif and seven conserved helicase motifs, and has both DNA-dependent ATPase and DNA unwinding activities. Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene. |
Source : | E.coli |
Species : | Human |
Tag : | His |
Protein length : | 693-1043a.a. |
Storage : | The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles. |
Storage Buffer : | 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol. |
Gene Name : | FBXO18 F-box protein, helicase, 18 [ Homo sapiens ] |
Official Symbol : | FBXO18 |
Synonyms : | FBXO18; F-box protein, helicase, 18; F box only protein 18; F-box only protein 18; FBH1; Fbx18; FLJ14590; F-box DNA helicase 1; F-box only protein, helicase, 18; MGC131916; MGC141935; MGC141937; |
Gene ID : | 84893 |
mRNA Refseq : | NM_032807 |
Protein Refseq : | NP_116196 |
MIM : | 607222 |
UniProt ID : | Q8NFZ0 |
Chromosome Location : | 10p15.1 |
Function : | ATP binding; ATP-dependent DNA helicase activity; DNA binding; helicase activity; hydrolase activity; nucleotide binding; |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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