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FBXO34

Official Full Name

F-box protein 34
Overview

Members of the F-box protein family, such as FBXO34, are characterized by an approximately 40-amino acid F-box motif.;SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as;protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination;targets through other protein interaction domains (Jin et al., 2004 (PubMed 15520277)).
Synonyms

FBXO34; F-box protein 34; F box only protein 34; F-box only protein 34; Fbx34; FLJ20725; CGI 301; F box protein 34; FBX34_HUMAN; protein CGI-301; CGI-301;

Type

Recombinant Proteins
Cell & Tissue Lysates
Protein Pre-coupled Magnetic Beads

Species

Chicken
Human
Mouse
Rhesus Macaque

Source

HEK293
In Vitro Cell Free System
Mammalian Cell
Wheat Germ

Tag

GST
His
His (Fc)
Avi
N/A

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	FBXO34-3939H	Recombinant Human FBXO34 Protein, GST-tagged	Wheat Germ	GST		Inquiry
Human	FBXO34-604HCL	Recombinant Human FBXO34 cell lysate		N/A		Inquiry
Human	FBXO34-4672HF	Recombinant Full Length Human FBXO34 Protein, GST-tagged	In Vitro Cell Free System	GST	711 amino acids	Inquiry
Mouse	FBXO34-5746M	Recombinant Mouse FBXO34 Protein	Mammalian Cell	His		Inquiry
Mouse	FBXO34-3162M	Recombinant Mouse FBXO34 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Mouse	FBXO34-3162M-B	Recombinant Mouse FBXO34 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Rhesus Macaque	FBXO34-1664R	Recombinant Rhesus monkey FBXO34 Protein, His-tagged	Mammalian Cell	His		Inquiry
Rhesus Macaque	FBXO34-1488R	Recombinant Rhesus Macaque FBXO34 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Rhesus Macaque	FBXO34-1488R-B	Recombinant Rhesus Macaque FBXO34 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Chicken	FBXO34-2876C	Recombinant Chicken FBXO34	Mammalian Cell	His		Inquiry

Involved Pathway
Protein Function
Interacting Protein
FBXO34 Related Articles

FBXO34 involved in several pathways and played different roles in them. We selected most pathways FBXO34 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with FBXO34 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein

FBXO34 has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by FBXO34 itself. We selected most functions FBXO34 had, and list some proteins which have the same functions with FBXO34. You can find most of the proteins on our site.

Function	Related Protein
protein binding	COPE;IL10RB;NCOA2;C1QL1;BTN2A2;APIP;FRMPD4;GCG;ARL2BP

FBXO34 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FBXO34 here. Most of them are supplied by our site. Hope this information will be useful for your research of FBXO34.

MTUS2; KRT40; MDFI; HSP90AB1; SKP1

Xiao, J; Zhang, T; et al. FBXL20-mediated Vps34 ubiquitination as a p53 controlled checkpoint in regulating autophagy and receptor degradation. GENES & DEVELOPMENT 29:184-196(2015).

Ikram, S; Durandet, M; et al. Functional redundancy and/or ongoing pseudogenization among F-box protein genes expressed in Arabidopsis male gametophyte. PLANT REPRODUCTION 27:95-107(2014).