fbxo25

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fbxo25

Official Full Name F-box protein 25
Background This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. Three alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Synonyms FBXO25; F-box protein 25; F box only protein 25; F-box only protein 25; FBX25; F-box protein Fbx25; MGC20256; MGC51975
    • Species :
    • Cynomolgus Monkey
    • Human
    • Mouse
    • Rat
    • Rhesus Macaque
    • Zebrafish
    • Source :
    • HEK293
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human FBXO25-3924H Recombinant Human FBXO25 Protein, GST-tagged Wheat Germ GST
    Human FBXO25-6303HCL Recombinant Human FBXO25 293 Cell Lysate HEK293 N/A
    Mouse FBXO25-5738M Recombinant Mouse FBXO25 Protein Mammalian Cell His
    Rat FBXO25-2291R Recombinant Rat FBXO25 Protein Mammalian Cell His
    Cynomolgus Monkey FBXO25-517C Recombinant Cynomolgus FBXO25 Protein, His-tagged Mammalian Cell His
    Rhesus Macaque FBXO25-1659R Recombinant Rhesus monkey FBXO25 Protein, His-tagged Mammalian Cell His
    Zebrafish FBXO25-11744Z Recombinant Zebrafish FBXO25 Mammalian Cell His

    fbxo25 involved in several pathways and played different roles in them. We selected most pathways fbxo25 participated on our site, such as FoxO signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with fbxo25 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    FoxO signaling pathway KRAS; CDKN1BB; SETD7; KLF2B; GRB2; TGFB2; GADD45AA; IGF1; MAP2K2B; NRAS

    fbxo25 has several biochemical functions, for example, actin binding, protein binding, ubiquitin-protein transferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by fbxo25 itself. We selected most functions fbxo25 had, and list some proteins which have the same functions with fbxo25. You can find most of the proteins on our site.

    Function Related Protein
    actin binding MYH10; PARK2; SPNA1; ACE; ACTN3A; MYO1H; SPATA32; MYH7B; LIMCH1A; PLECA
    protein binding ZNF404; SYT2; UBQLN2; ZBTB16; PPARD; MERTK; STOML1; FRS2; METTL15; SIN3A
    ubiquitin-protein transferase activity TRIM5; RNF146; TRIM27; UBA7; ZNF738; UBE2A; TRIM24; MARCH6; UBE2D4; UBE2K

    fbxo25 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with fbxo25 here. Most of them are supplied by our site. Hope this information will be useful for your research of fbxo25.

    CUL1; SKP1; ACTB; b4dyc6_human; HSP90AA1; HSP90AB1; FKBP5; HSP90AB1; PPP5C; ORC4; EP300; CAND1

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