FBXO2
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Official Full Name
F-box protein 2
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Overview
This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-bo -
Synonyms
FBXO2; F-box protein 2; F box only protein 2 , OCP1, organ of Corti protein 1; F-box only protein 2; Fbg1; Fbs1; FBX2; Nfb42; F-box gene 1; organ of Corti protein 1; OCP1;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Human
- Mouse
- E.coli
- HEK293
- HEK293T
- In Vitro Cell Free System
- Mammalian cells
- Wheat Germ
- Flag
- GST
- His
- His (Fc)
- Avi
- SUMO
- Myc
- DDK
- N/A
- N
- Involved Pathway
- Protein Function
- Interacting Protein
FBXO2 involved in several pathways and played different roles in them. We selected most pathways FBXO2 participated on our site, such as Ubiquitin mediated proteolysis, Protein processing in endoplasmic reticulum, which may be useful for your reference. Also, other proteins which involved in the same pathway with FBXO2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Ubiquitin mediated proteolysis | UBE2J1;CDC34A;TRIP12;XIAP;KLHL13;UBE3C;UBE2D2A;SMURF1;UBE1Y1 |
| Protein processing in endoplasmic reticulum | PDIA4;MAP3K5;UBE4B;ATXN3L;RRBP1A;HSP70;HSPA5;BCL2;EDEM3 |
FBXO2 has several biochemical functions, for example, beta-amyloid binding, carbohydrate binding, glycoprotein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by FBXO2 itself. We selected most functions FBXO2 had, and list some proteins which have the same functions with FBXO2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| beta-amyloid binding | SORL1;NGFR;OLFM1;CD74;HSD17B10;COL25A1;GPRASP2;Apba1;BACE2 |
| carbohydrate binding | ASGR1;Cd24a;LGALS9C;FBXO2;CLEC10A;FCNA;CLEC2G;CLEC19A;MLEC |
| glycoprotein binding | LACRT;FOXRED2;RGMA;Shh;THBS1;PTBP3;RASA1;BMPR1A;FYN |
| protein binding | GPR19;FAM153C;TRAF2;SUPT4H1;EPN2;PRR13;SUN2;CEP70;KCTD14 |
| ubiquitin-protein transferase activity | FBXL7;UBR4;MARCH1;UBE2H;RNF146;RNF213;UBE2O;MUL1A;BIRC5 |
FBXO2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FBXO2 here. Most of them are supplied by our site. Hope this information will be useful for your research of FBXO2.
SKP1; IQCB1
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