FBXO44
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Official Full Name
F-box protein 44
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Overview
The F box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1 cullin F box), which function in phosphorylation dependent ubiquitination. The F box proteins are divided into 3 classes: Fbws containing WD40 domains, Fbls containing leucine rich repeats, and Fbxs containing either different protein protein interaction modules or no recognizable motifs. FBXO44 belongs to the Fbxs class. -
Synonyms
FBXO44; F-box protein 44; F-box only protein 44; F-box gene 3; OTTHUMP00000002063; OTTHUMP00000002064; OTTHUMP00000002065; OTTHUMP00000002242; OTTHUMP00000035894; OTTHUMP00000035896; F-box protein FBX30; F-box/G-domain protein 3;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Human
- Mouse
- Rhesus Macaque
- Zebrafish
- E.coli
- HEK293
- HEK293T
- In Vitro Cell Free System
- Mammalian Cell
- Wheat Germ
- GST
- His
- His (Fc)
- Avi
- Myc
- DDK
- N/A
- Involved Pathway
- Protein Function
- Interacting Protein
FBXO44 involved in several pathways and played different roles in them. We selected most pathways FBXO44 participated on our site, such as Adaptive Immune System, Antigen processing: Ubiquitination &, Proteasome degradation, which may be useful for your reference. Also, other proteins which involved in the same pathway with FBXO44 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Adaptive Immune System | KIF2B;KIF26A;LAIR2;CDKN1A;CD200R4;CLTC;KIF22;THEM4;CTSL2 |
| Antigen processing: Ubiquitination & | BLMH;GAN;KLHL20;ASB4;SPSB1;HECTD3;RNF144B;ASB2;UBE2U |
| Proteasome degradation | UBE2U;SPSB1;ASB10;LRRC41;LTN1;SPSB2;ASB4;BLMH;ARIH2 |
| Class I MHC mediated antigen processing & | PJA2;TRIM69;SPSB1;TRIM9;UBR1;SH3RF1;FCGR1B;WWP1;SPSB2 |
| presentation | TRIM69;UBA5;ERAP1;UBE2U;ASB14;LTN1;RNF138;MKRN1;ASB9 |
| Immune System | MAP3K8;CASPBL;KIF4;XAF1;KLRG1;KIF5B;ACTR2B;SAMHD1;KIF2A |
FBXO44 has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by FBXO44 itself. We selected most functions FBXO44 had, and list some proteins which have the same functions with FBXO44. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | ZFYVE20;EXOC3L;COX8A;NAE1;SULT1C2;PPP6C;TNFSF10;CD22;PPP2R5C |
FBXO44 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FBXO44 here. Most of them are supplied by our site. Hope this information will be useful for your research of FBXO44.
SKP1; C17orf59; SERTAD3; COPS6
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