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Recombinant Human Ephrin-B1

Cat. No.: EFNB1-152H
Product Overview: Recombinant Human Ephrin B1 protein expressed inE.coliencodes amino acids 136-347 and has a molecular mass of 47 kDa.
Description: Ephrins are the ligands which bind to the Eph receptor subfamily, the largest group of the receptor tyrosine kinase family. Both ephrins and Eph receptors are broadly expressed through the ectoderm, mesoderm, and endoderm of vertebrate embryos. Two classes of ephrins exist: Class A ephrins are tethered to the membrane by a GPI linkage and bind primarily to EphA receptors; Class B ephrins contain a membrane-spanning region and bind predominantly to EphB receptors.
Source: Recombinant Human Ephrin B1 protein encoding a.a. 136-347 expressed inE.coli.
Formulation: Recombinant Human Ephrin B1 protein at 100µg/ml in 50mM Tris-Acetate, pH7.5, 1mM EDTA and 20% Glycerol.
Application And Suggested Dilutions: •ELISA •Inhibition Assays •Western Blotting
Characterization: On SDS-PAGE commassie blue stained gel, the purified recombinant protein shows a band at 47 kDa.
Storage & Stability: Store vial at -20°Cto -80°C. When stored at the recommended temperature, this protein is stable for 12 months.
Gene Name: EFNB1 ephrin-B1 [ Homo sapiens ]
Synonyms: EFNB1; ephrin-B1; CFND; CFNS; EFL3; EPLG2; Elk-L; LERK2; EFL-3; MGC8782; LERK-2; OTTHUMP00000023456; ELK ligand; EPH-related receptor tyrosine kinase ligand; craniofrontonasal syndrome (craniofrontonasal dysplasia); ligand of eph-related kinase 2; ELK-L
Gene ID: 1947
mRNA Refseq: NM_004429
Protein Refseq: NP_004420
MIM: 300035
UniProt ID: P98172
Chromosome Location: Xq12
Pathway: Axon guidance
Function: ephrin receptor binding; protein binding

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