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Official Full Name Ephrin-B2
Background Ephrin type-B receptor 2 is a protein that in humans is encoded by the EPHB2 gene. Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. The protein encoded by this gene is a receptor for ephrin-B family members.
Synonyms EPHB2; EPH receptor B2; DRT; EK5; ERK; CAPB; Hek5; PCBC; EPHT3; Tyro5; MGC87492; ephrin type-B receptor 2; EPH-like kinase 5; eph tyrosine kinase 3; elk-related tyrosine kinase; protein-tyrosine kinase HEK5; tyrosine-protein kinase TYRO5; renal carcinoma antigen NY-REN-47; tyrosine-protein kinase receptor EPH-3; developmentally-regulated Eph-related tyrosine kinase; EphB2; EC=; Developmentally-regulated Eph-related tyrosine kinase; CAPB; PCBC; EFN B2; EFNB 2; EFNB2; Eph related receptor tyrosine kinase ligand 5; EPH-related receptor tyrosine kinase ligand 5; Ephrin-B2; EphrinB2; EPLG 5; EPLG5; Htk L; HTK ligand; HTK-L; HTKL; LERK 5; LERK-5; LERK5; Ligand of eph related kinase 5 antibody; MGC126226; MGC126227; MGC126228; OTTMUSP00000024973; Htk-L; ELF-2; NLERK-1
    • Species :
    • Canine
    • Chicken
    • Human
    • Mouse
    • Rat
    • Source :
    • E.coli
    • HEK293
    • HEK293E
    • HEK293T
    • Human Cell
    • Insect Cell
    • Mammalian Cell
    • Mammalian cells
    • Wheat Germ
    • Tag :
    • Fc
    • Fc Chimera
    • FC/His
    • His
    • GST
    • Myc/DDK
    • Myc
    • DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human EFNB2-001H Recombinant Human EFNB2 Protein, Fc-His-tagged HEK293E FC/His
    Human EFNB2-1134H Recombinant Human EFNB2 protein, His & GST-tagged E.coli His/GST
    Human EFNB2-1378H Recombinant Human EFNB2 Protein, MYC/DDK-tagged HEK293 Myc/DDK
    Human EFNB2-2032H Recombinant Human EFNB2 Protein, His-tagged HEK293 His
    Human EFNB2-2240H Recombinant Human EFNB2, Fc-His tagged Human Cell Fc/His
    Human EFNB2-272H Recombinant Human EFNB2, ENLYFQ tagged Human Cell His
    Human EFNB2-3104H Recombinant Human EFNB2 Protein, GST-tagged Wheat Germ GST
    Human EFNB2-3191H Recombinant Human EFNB2, His tagged Human Cell His
    Human EFNB2-358H Recombinant Human EFNB2 Protein HEK293 N/A
    Human EFNB2-480H Recombinant Human EFNB2 Mammalian Cell His
    Human EFNB2-5264H Recombinant Human Ephrin-B2, His-tagged HEK293E His
    Human EFNB2-6870H Recombinant Human Ephrin-B2, His-tagged E.coli His
    Human EFNB2-936HCL Recombinant Human EFNB2 cell lysate Human Cell N/A
    Mouse Efnb2-1377M Recombinant Mouse Efnb2 Protein, Fc/His-tagged HEK293 Fc/His
    Mouse Efnb2-1734M Recombinant Mouse Ephrin B2, Fc-His Mammalian cells Fc/His
    Mouse Efnb2-198M Recombinant Mouse Efnb2, Fc Chimera Mammalian cells Fc Chimera
    Mouse Efnb2-199M Recombinant Mouse Efnb2, Fc Chimera, Biotinylated Mammalian cells Fc Chimera
    Mouse EFNB2-2405MCL Recombinant Mouse EFNB2 cell lysate Human Cell N/A
    Mouse Efnb2-2756M Recombinant Mouse Efnb2 Protein, Myc/DDK-tagged HEK293T Myc/DDK
    Mouse Efnb2-3315M Recombinant Mouse Efnb2, His tagged Human Cell His
    Mouse Efnb2-367M Recombinant Mouse Efnb2 Protein, His-tagged Insect Cell His
    Mouse Efnb2-7194M Recombinant Mouse Efnb2 Protein, His-tagged Insect Cell His
    Mouse EFNB2-882M Recombinant Mouse EFNB2 Protein, Fc-tagged HEK293 Fc
    Rat EFNB2-1078R Recombinant Rat EFNB2 Protein, Fc-tagged HEK293 Fc
    Rat EFNB2-1540RCL Recombinant Rat EFNB2 cell lysate Human Cell N/A
    Rat Efnb2-7435R Recombinant Rat Efnb2, His tagged Human Cell His
    Canine EFNB2-175C Recombinant Canine EFNB2, Fc tagged Human Cell His
    Canine EFNB2-297C Recombinant Canine EFNB2, His tagged Human Cell Fc
    Canine EFNB2-965CCL Recombinant Canine EFNB2 cell lysate Human Cell N/A
    Chicken EFNB2-6387C Recombinant Chicken EFNB2 Mammalian Cell His

    Efnb2 involved in several pathways and played different roles in them. We selected most pathways Efnb2 participated on our site, such as Axon guidance, Developmental Biology, EPH-Ephrin signaling, which may be useful for your reference. Also, other proteins which involved in the same pathway with Efnb2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Axon guidance SEMA6D; MAPK1; CXCR4; AP2S1; CHL1; FRS3; NTN1; MARK3; EFNB2A; MYL12B
    Developmental Biology ST8SIA2; RASGRP1; NADL1.1; EFNA1; HELZ2; SCN2A; NRP1A; SCN3B; EFNB1; HIF3A
    EPH-Ephrin signaling EFNA3; AP2A2; ARPC1B; CFL1; EFNB2A; ACTR2B; EFNA3B; EPHB4B; SDCBP; EFNA1
    EPH-ephrin mediated repulsion of cells AP2B1; EPHA2A; EFNB3B; EFNB1; EFNA5; EPHB4B; EPHB3A; EFNB2A; EFNA2; EFNB3
    EPHB forward signaling EFNB3; ITSN1; GRB7; EFNA5; EFNB2; EFNB1
    EPHB-mediated forward signaling EFNB3B; EPHB4A; KALRNB; CFL1; ARPC1A; ARPC3; ARPC5; EFNB3; ACTR2; EFNB1
    Ephrin B reverse signaling EFNB2; PTPN13; EFNB1
    Ephrin signaling EFNB1; EPHB4A; EPHB4B; MYL12A; EFNB2A; EFNB2; EFNB3; SDCBP; EPHB3A; EFNB3B

    Efnb2 has several biochemical functions, for example, ephrin receptor binding, protein binding, virus receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by Efnb2 itself. We selected most functions Efnb2 had, and list some proteins which have the same functions with Efnb2. You can find most of the proteins on our site.

    Function Related Protein
    ephrin receptor binding Anks1; SIPA1L1; ANKS1B; EFNB2; EFNA1A; NTRK3; EFNA4; EFNA3; EFNA1B; EPHA4
    protein binding SNRPE; COPE; MAP4K5; TEX10; MTA3; CHPF; NBN; PPP1R8; RPS6; KRT20
    virus receptor activity SLAMF1; SIVA1; MRC1; HLA-DRB1; SLC10A1; SERPINB4; SLC20A2; ITGA5; ITGB5; EFNB3

    Efnb2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Efnb2 here. Most of them are supplied by our site. Hope this information will be useful for your research of Efnb2.


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