Recombinant Human RGS21, His-tagged

• Cat.No.: RGS21-29966TH
• Product Overview: Recombinant full-length Human RGS21 with an N terminal His tag; 176aa, 20.2kDa inclusive of tag.

Specification

• Description: Regulator of G protein signaling (RGS) proteins are regulatory and structural components of G protein-coupled receptor complexes. RGS proteins are GTPase-activating proteins for Gi (see GNAI1; MIM 139310) and Gq (see GNAQ; MIM 600998) class G-alpha proteins. They accelerate transit through the cycle of GTP binding and hydrolysis and thereby accelerate signaling kinetics and termination.
• Protein length: 152 amino acids
• Conjugation: HIS
• Molecular Weight: 20.200kDa inclusive of tags
• Source: E. coli
• Tissue specificity: Expressed ubiquitously.
• Form: Liquid
• Purity: >90% by SDS-PAGE
• Storage buffer: pH: 8.00Constituents:0.32% Tris HCl, 0.02% DTT, 30% Glycerol, 0.58% Sodium chloride
• Storage: Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
• Sequences of amino acids: MGSSHHHHHH SSGLVPRGSH MGSH MPVKCC FYRSPTAETM TWSENMDTLL ANQAGLDAFR IFLKSEFSEE NVEFWLACED FKKTKNADKI ASKAKMIYSE FIEADAPKEI NIDFGTRDLI SKNIAEPTLK CFDEAQKLIY CLMAKDSFPR FLKSEIYKKL VNSQQVPNHK KWLPFL
• Sequence Similarities: Contains 1 RGS domain.

Gene Information

• Gene Name: RGS21 regulator of G-protein signaling 21 [ Homo sapiens ]
• Official Symbol: RGS21
• Synonyms: RGS21; regulator of G-protein signaling 21; regulator of G protein signalling 21
• Gene ID: 431704
• mRNA Refseq: NM_001039152
• Protein Refseq: NP_001034241
• MIM: 612407
• Uniprot ID: Q2M5E4
• Chromosome Location: 1q31.1
• Pathway: G alpha (i) signalling events, organism-specific biosystem; G alpha (q) signalling events, organism-specific biosystem; GPCR downstream signaling, organism-specific biosystem; Signal Transduction, organism-specific biosystem; Signaling by GPCR, organism-specific biosystem
• Function: GTPase activator activity; signal transducer activity