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RGS19

  • Official Full Name

    regulator of G-protein signaling 19

  • Overview

    G proteins mediate a number of cellular processes. The protein encoded by this gene belongs to the RGS (regulators of G-protein signaling) family and specifically interacts with G protein, GAI3. This protein is a guanosine triphosphatase-activating protein that functions to down-regulate Galpha i/Galpha q-linked signaling. Alternatively spliced transcript variants encoding the same protein isoform have been found for this gene.
  • Synonyms

    RGS19; regulator of G-protein signaling 19; regulator of G protein signalling 19; GAIP; RGSGAIP; G alpha interacting protein; GNAI3IP; Guanine nucleotide binding protein alpha inhibiting activity polypeptide 3 interacting protein; G-alpha-interacting protein; G protein signalling regulator 19; regulator of G-protein signalling 19;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Mouse
  • Rat
  • Rhesus Macaque
  • Zebrafish
  • E.coli
  • HEK293
  • HEK293T
  • Mammalian Cell
  • His
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • N/A
  • T7
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human RGS19-30744TH Recombinant Human RGS19, His-tagged E.coli His 217 amino acids
Human RGS19-2978H Recombinant Human RGS19, T7-tagged E.coli T7
Human RGS19-3363H Recombinant Human Regulator Of G-protein Signaling 19, His-tagged E.coli His
Human RGS19-2379HCL Recombinant Human RGS19 293 Cell Lysate HEK293 N/A
Human RGS19-2380HCL Recombinant Human RGS19 293 Cell Lysate HEK293 N/A
Mouse Rgs19-5495M Recombinant Mouse Rgs19 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Rat RGS19-5017R Recombinant Rat RGS19 Protein Mammalian Cell His
Rat RGS19-4676R-B Recombinant Rat RGS19 Protein Pre-coupled Magnetic Beads HEK293
Rat RGS19-4676R Recombinant Rat RGS19 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque RGS19-3874R Recombinant Rhesus monkey RGS19 Protein, His-tagged Mammalian Cell His
Rhesus Macaque RGS19-3691R-B Recombinant Rhesus Macaque RGS19 Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque RGS19-3691R Recombinant Rhesus Macaque RGS19 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Zebrafish RGS19-7109Z Recombinant Zebrafish RGS19 Mammalian Cell His
Chicken RGS19-5802C Recombinant Chicken RGS19 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein

RGS19 involved in several pathways and played different roles in them. We selected most pathways RGS19 participated on our site, such as Calcium Regulation in the Cardiac Cell, G alpha (i) signalling events, G alpha (q) signalling events, which may be useful for your reference. Also, other proteins which involved in the same pathway with RGS19 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Calcium Regulation in the Cardiac CellRGS19;CX30.3;RGS18;CHRM5;YWHAQ;FKBP1A;ADRB1;CX44.1;GJA5
G alpha (i) signalling eventsPYYA;OXGR1;CASR;PYY;OPN5;OXGR1A.1;PTGDR2;SST;AGT
G alpha (q) signalling eventsANXA1B;HCRT;FPR-RS4;RGS19;CYSLTR1;GRP;APPB;NPS;EDN2
G alpha (z) signalling eventsADRA2A;RGS19;ADRA2B;RGS4;RGS17;RGS20;ADRA2C
GPCR downstream signalingRAMP1;PENKB;OR7D2;RAMP3;ADM;FPR-RS6;DRD2;CNR2;CYSLTR1
Gastrin-CREB signalling pathway via PKC and MAPKGRP;EDN1;NPS;MGLL;DGKQ;LPAR1;DGKA;RGS19;QRFP
Myometrial Relaxation and Contraction PathwaysRGS14;ACTA1;RGS20;CNN1;RGS16;IGFBP6;IGFBP4;RAMP1;IGFBP5
Neurotrophic factor-mediated Trk receptor signalingRIT2;RIT1;GIPC1;DYNLT1;MCF2L;RGS19;FAIM

RGS19 has several biochemical functions, for example, G-protein alpha-subunit binding, GTPase activator activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by RGS19 itself. We selected most functions RGS19 had, and list some proteins which have the same functions with RGS19. You can find most of the proteins on our site.

Function Related Protein
G-protein alpha-subunit bindingADRB2;RIC8B;PPP5C;RIC8A;CRHR1;F2R;LPAR3;RIC8;RGS19
GTPase activator activityRGS5;SIPA1L1;DEPDC1B;SRGAP1;CHN2;RAP1GDS1;HTR2B;SH3BP1;ARHGAP31
protein bindingLILRB3;OLFM2;ITGA1;INSR;PARP1;Car8;GATSL3;CCNC;DR1

RGS19 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with RGS19 here. Most of them are supplied by our site. Hope this information will be useful for your research of RGS19.

Gnai3; GNAI2; MAPK6; q81s67_bacan; MZT1

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