Rgs12
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Official Full Name
regulator of G-protein signaling 12
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| RGS12-5014R | Recombinant Rat RGS12 Protein | Mammalian Cells | Rat | His |
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| RGS12-1501HCL | Recombinant Human RGS12 cell lysate | Human | Non |
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| RGS12-4673R | Recombinant Rat RGS12 Protein, His (Fc)-Avi-tagged | HEK293 | Rat | Avi&Fc&His |
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| RGS12-4673R-B | Recombinant Rat RGS12 Protein Pre-coupled Magnetic Beads | HEK293 | Rat |
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Involved Pathway
Rgs12 involved in several pathways and played different roles in them. We selected most pathways Rgs12 participated on our site, such as G alpha (i) signalling events,GPCR downstream signaling,Signal Transduction, which may be useful for your reference. Also, other proteins which involved in the same pathway with Rgs12 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Signal Transduction | RAMP2,CALML4,IFT172,NTS,TAC1,CCL35.1,CXCL11.8,CHRDL1,FMNL2,BBS13 |
| GPCR downstream signaling | PIK3R6,SSTR2,PTHLHA,ARHGEF17,GPR18,ADM2,ANXA1C,CHRM5,RLN3A,CHRM3 |
| Signaling by GPCR | PNOC,ANXA1C,GPR39,PENKA,KEL,RGS18,VIP,RGS21,OR10A5,XK |
| G alpha (i) signalling events | PMCH,ADRA2B,RLN3A,RGS11,ADRA2A,RHOL,CCR9,RGS14,NPB,DRD2 |
Protein Function
Rgs12 has several biochemical functions, for example, GTPase activator activity,GTPase regulator activity,receptor signaling protein activity. Some of the functions are cooperated with other proteins, some of the functions could acted by Rgs12 itself. We selected most functions Rgs12 had, and list some proteins which have the same functions with Rgs12. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| GTPase activator activity | ASAP1,TBC1D3,RP2,ARHGAP5,RALGAPA2,CHML,ADAP2,RGS12B,TBC1D10C,RGS7 |
| GTPase regulator activity | RGS12B,GPSM3,TSC1,PCP2,RUNDC3A,WAS,WASL,TSC1A,RALGDS,TSC1B |
| receptor signaling protein activity | DOK5,GNAZ,DAXX,PLCE1,TGFBR1,NSMAF,PLCG1,CD3E,BAG4,CD19 |
Interacting Protein
Rgs12 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Rgs12 here. Most of them are supplied by our site. Hope this information will be useful for your research of Rgs12.
ITGB3;BCR;Cacna1b
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References
- Appleton, KM; Bigham, KJ; et al. Development of inhibitors of heterotrimeric G alpha(i) subunits. BIOORGANIC & MEDICINAL CHEMISTRY 22:3423-3434(2014).
- Guipponi, M; Santoni, FA; et al. Exome Sequencing in 53 Sporadic Cases of Schizophrenia Identifies 18 Putative Candidate Genes. PLOS ONE 9:-(2014).
