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RGS4

  • Official Full Name

    regulator of G-protein signaling 4

  • Overview

    Regulators of G protein signaling (RGS) are a family of about 40 proteins that determine the signaling amplitude and duration of G protein-coupled receptor signaling via modulation of the GTPase activity of G proteins. Each RGS has a distinct structure, e
  • Synonyms

    RGS4; regulator of G-protein signaling 4; regulator of G protein signalling 4 , schizophrenia disorder 9 , SCZD9; schizophrenia disorder 9; RGP4; SCZD9; MGC2124; MGC60244; DKFZp761F1924;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Mouse
  • Rat
  • Zebrafish
  • E.coli
  • HEK293
  • HEK293T
  • Mammalian Cell
  • Mammalian cells
  • Flag
  • GST
  • His
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human RGS4-1563H Recombinant Human Regulator Of G-protein Signaling 4, His-tagged E.coli His
Human RGS4-29969TH Recombinant Human RGS4 E.coli N/A
Human RGS4-3616H Recombinant Human RGS4, His-tagged E.coli His
Human RGS4-2372HCL Recombinant Human RGS4 293 Cell Lysate HEK293 N/A
Human RGS4-1887H Recombinant Human RGS4 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human RGS4-1188H Recombinant Human RGS4 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human RGS4-301208H Recombinant Human RGS4 protein, GST-tagged E.coli GST His21-Cys71
Human RGS4-1464HFL Recombinant Full Length Human RGS4 Protein, C-Flag-tagged Mammalian cells Flag
Human RGS4-6177H Recombinant Human RGS4 Protein (Ser38-Ala205), N-His tagged E.coli N-His Ser38-Ala205
Human RGS4-1887H-B Recombinant Human RGS4 Protein Pre-coupled Magnetic Beads HEK293
Mouse RGS4-14145M Recombinant Mouse RGS4 Protein Mammalian Cell His
Mouse RGS4-7568M-B Recombinant Mouse RGS4 Protein Pre-coupled Magnetic Beads HEK293
Mouse Rgs4-5499M Recombinant Mouse Rgs4 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Mouse RGS4-7568M Recombinant Mouse RGS4 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat RGS4-5020R Recombinant Rat RGS4 Protein Mammalian Cell His
Rat RGS4-4679R Recombinant Rat RGS4 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat RGS4-4679R-B Recombinant Rat RGS4 Protein Pre-coupled Magnetic Beads HEK293
Zebrafish RGS4-9906Z Recombinant Zebrafish RGS4 Mammalian Cell His
Chicken RGS4-5955C Recombinant Chicken RGS4 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • RGS4 Related Articles

RGS4 involved in several pathways and played different roles in them. We selected most pathways RGS4 participated on our site, such as Calcium Regulation in the Cardiac Cell, G alpha (i) signalling events, G alpha (z) signalling events, which may be useful for your reference. Also, other proteins which involved in the same pathway with RGS4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Calcium Regulation in the Cardiac CellADRA1D;RGS6;ADRa1A;GJA10;GJA3;ADRB2;YWHAQ;RGS4;RGS10
G alpha (i) signalling eventsANXA1B;HCAR1-2;ADRA2C;PYYA;ANXA1;TAS2R16;PYY;ADORA1;CASR
G alpha (z) signalling eventsADRA2B;ADRA2C;RGS4;RGS17;ADRA2A;RGS19;RGS20
GPCR downstream signalingARHGEF1B;LTB4R;GHRH;RGS17;OPN1SW1;CALCB;PROKR2;RGS21;FPR-RS4
Myometrial Relaxation and Contraction PathwaysRGS7;CRHR1;RGS16;IGFBP4;RAMP1;RGS4;CNN1;IGFBP6;CNN2
Signal TransductionTAS2R7;WNT8-2;BCL9;RLBP1B;IGF2BP1;ARHGAP12B;APOA4A;NOTUM1A;ARHGAP11A
Signaling by GPCRRXFP2B;PROK2;PNOC;FGD4;RGS11;GPR120;PPY;RAMP3;OPN1LW2

RGS4 has several biochemical functions, for example, G-protein alpha-subunit binding, GTPase activator activity, calmodulin binding. Some of the functions are cooperated with other proteins, some of the functions could acted by RGS4 itself. We selected most functions RGS4 had, and list some proteins which have the same functions with RGS4. You can find most of the proteins on our site.

Function Related Protein
G-protein alpha-subunit bindingRIC8;ADRB2;ARHGEF11;IGF1R;CRHR1;LPAR3;RIC8A;HTR2A;F2RL1
GTPase activator activityRGS4;BCR;ARHGAP22;TBC1D2B;ASAP2;ARHGAP29;ARHGAP42;RGS19;PGAM5
calmodulin bindingRRAD;KCNN2;MYO5A;PDE1A;ADD1;MKNK2;PPP3CB;MARCKS;ADD2

RGS4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with RGS4 here. Most of them are supplied by our site. Hope this information will be useful for your research of RGS4.

EGFR

Shirley, MD; Tang, H; et al. Sturge-Weber Syndrome and Port-Wine Stains Caused by Somatic Mutation in GNAQ. NEW ENGLAND JOURNAL OF MEDICINE 368:1971-1979(2013).
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