Recombinant Human RGS21, His-tagged

• Cat.No.: RGS21-3615H
• Product Overview: Recombinant human RGS21 human, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Description: Regulator of G-protein signaling 21, also known as RGS21, is a RGS family member and regulatory molecules that act as GTPase activating proteins for G alpha subunits of heterotrimeric G proteins. This protein inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form.
• Form: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT,30% glycerol, 0.1M NaCl
• Molecular Weight: 20.2 kDa (176aa), confirmed by MALDI-TOF
• Purity: > 90% by SDS - PAGE
• Concentration: 1 mg/ml (determined by Bradford assay)
• Sequences of amino acids: MGSSHHHHHH SSGLVPRGSH MGSHMPVKCC FYRSPTAETM TWSENMDTLL ANQAGLDAFR IFLKSEFSEE NVEFWLACED FKKTKNADKIASKAKMIYSE FIEADAPKEI NIDFGTRDLI SKNIAEPTLK CFDEAQKLIY CLMAKDSFPR FLKSEIYKKL VNSQQVPNHK KWLPFL
• Storage: Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.

Gene Information

• Gene Name: RGS21 regulator of G-protein signaling 21 [ Homo sapiens ]
• Official Symbol: RGS21
• Synonyms: RGS21; regulator of G-protein signaling 21;OTTHUMP00000225020;regulator of G-protein signalling 21
• Gene ID: 431704
• mRNA Refseq: NM_001039152
• Protein Refseq: NP_001034241
• MIM: 612407
• UniProt ID: Q2M5E4
• Chromosome Location: 1q31.1
• Function: GTPase activator activity; signal transducer activity