Recombinant Human ALG14, His-tagged

• Cat.No.: ALG14-9574H
• Product Overview: Recombinant Human ALG14 protein, fused to His-tag, was expressed in E.coli and purified by Ni-sepharose.

Specification

• Description: Asparagine (N)-glycosylation is an essential modification that regulates protein folding and stability. ALG13 and ALG14 (MIM 612866) constitute the UDP-GlcNAc transferase, which catalyzes a key step in endoplasmic reticulum N-linked glycosylation (Averbeck et al., 2007 [PubMed 17686769]).
• Source: E.coli
• Species: Human
• Tag: His
• Protein length: 27-216a.a.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol.

Gene Information

• Gene Name: ALG14 asparagine-linked glycosylation 14 homolog (S. cerevisiae) [ Homo sapiens ]
• Official Symbol: ALG14
• Synonyms: asparagine-linked glycosylation 14 homolog (S. cerevisiae); MGC19780; asparagine-linked glycosylation 14 homolog (yeast); UDP-N-acetylglucosamine transferase subunit ALG14 homolog; ALG14
• Gene ID: 199857
• mRNA Refseq: NM_144988.3
• Protein Refseq: NP_659425.1
• MIM: 612866
• UniProt ID: Q96F25
• Chromosome Location: 1p21.3
• Pathway: Asparagine N-linked glycosylation, organism-specific biosystem; Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein, organism-specific biosystem; Metabolism of proteins, organism-specific biosystem; N-Glycan biosynthesis, organism-specific biosystem; N-Glycan biosynthesis, conserved biosystem; N-glycan precursor biosynthesis, organism-specific biosystem; N-glycan precursor biosynthesis, conserved biosystem